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The map label for this gene is hypD [H]

Identifier: 57233766

GI number: 57233766

Start: 1304937

End: 1306031

Strand: Direct

Name: hypD [H]

Synonym: DET1434

Alternate gene names: 57233766

Gene position: 1304937-1306031 (Clockwise)

Preceding gene: 57233775

Following gene: 57233765

Centisome position: 88.79

GC content: 53.33

Gene sequence:

>1095_bases
GTGAATTTCATAGAGGAATTCCGCAGCAGCCAGTCAGGACGCACCCTGCTGGAATATATAAACAAACGTTCCACCAAGCC
TGCCCGCTTTATGGAGTTTTGCGGCGGGCATACCGTAGCCATTTTCCGCTACGGCATCCGCCAGCTGCTGCCGCCCCATA
TTGAAATGCTGTCAGGGCCGGGCTGCCCTGTTTGTGTAACCTCTACCGCCGACCTGGACAAAGTCATAGCCCTGTCCAGG
CTGCCAGGGGTTATAATCTGCTCATTCGGAGACCTGCTAAGGGTTCCCTCCAGCCGCCAAAGCCTGCTGGAAGTGCGGGC
GGAAGGGGCGGACGTACGTATTGTCTACTCTACCATGGACGCACTGGAGATAGCCCGCCAGAACCCCTTGAAAAAGGTTA
TCTTTGTGGGTATAGGTTTTGAAACCACCGCCCCCACCATTGCCGCTTCGGTAATACAGGCTCGTAATCAGGGGCTTGCT
AATTATTATGTAATGTCAATTCACAAAATAACCCCTCCCGTTATGCGGGCGATACTGGATGCAGGTGAAACCCGCCTTTC
GGGCATAATCTGCCCCGGCCATGTTTCTTCTATTACCGGCAGCAATGCCTGGGAATTTATTCCAGAGGAATACCATCTGG
CTTGTGCCGTGTCAGGCTTTGAAAGCCTGGACATACTCTACTGTGTTAAGTCTCTGGTAGACCAGGTGGAAGACGCAACT
CCCCGTCTGGACGTCAGCTATTCACGGGCAGTCAAACCTGAAGGCAATACTGCCGCCCTTAAGATTATGGATGAAGTATT
TGATATCTGCCCGGCCAACTGGCGGGGGATAGGTATTTTACCCCAAAGCGGCCTCTGCCTGCGGCCTGAATTTGCCGCTT
TTGATGCCGAAAAAAACTTTGAGATAAAACTTTCCGAGCCCAGCCGCGAAACACCCGGCTGTCTGTGCGGTGAAATTATC
AAAGGCACCCGGACACCTCTGGAATGCAAGCTTTTTTCAAAGGTCTGCACCCCGGAAAACCCGGTCGGGCCGTGCATGGT
CTCTTCCGAGGGCACCTGCGCCGCCTATTACCACTACGGAGGCAAACTTGGATAA

Upstream 100 bases:

>100_bases
TTACGTACTGCTTCACACCGGCTATGCCATACAGGTAATAGACGAAAAAGACGCTTTGGAAACCCTGTCTATATTCAAGC
AGATGGAGATGCTGTAAAGA

Downstream 100 bases:

>100_bases
AACCAAAATCCTGCTGGCCCACGGTTCGGGCGGGCGCTTAACCCATGACCTTATCACAAAGCACCTTGTCCAGTCTCTGT
CCAACCCGCTCCTAAACAAG

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNFIEEFRSSQSGRTLLEYINKRSTKPARFMEFCGGHTVAIFRYGIRQLLPPHIEMLSGPGCPVCVTSTADLDKVIALSR
LPGVIICSFGDLLRVPSSRQSLLEVRAEGADVRIVYSTMDALEIARQNPLKKVIFVGIGFETTAPTIAASVIQARNQGLA
NYYVMSIHKITPPVMRAILDAGETRLSGIICPGHVSSITGSNAWEFIPEEYHLACAVSGFESLDILYCVKSLVDQVEDAT
PRLDVSYSRAVKPEGNTAALKIMDEVFDICPANWRGIGILPQSGLCLRPEFAAFDAEKNFEIKLSEPSRETPGCLCGEII
KGTRTPLECKLFSKVCTPENPVGPCMVSSEGTCAAYYHYGGKLG

Sequences:

>Translated_364_residues
MNFIEEFRSSQSGRTLLEYINKRSTKPARFMEFCGGHTVAIFRYGIRQLLPPHIEMLSGPGCPVCVTSTADLDKVIALSR
LPGVIICSFGDLLRVPSSRQSLLEVRAEGADVRIVYSTMDALEIARQNPLKKVIFVGIGFETTAPTIAASVIQARNQGLA
NYYVMSIHKITPPVMRAILDAGETRLSGIICPGHVSSITGSNAWEFIPEEYHLACAVSGFESLDILYCVKSLVDQVEDAT
PRLDVSYSRAVKPEGNTAALKIMDEVFDICPANWRGIGILPQSGLCLRPEFAAFDAEKNFEIKLSEPSRETPGCLCGEII
KGTRTPLECKLFSKVCTPENPVGPCMVSSEGTCAAYYHYGGKLG
>Mature_364_residues
MNFIEEFRSSQSGRTLLEYINKRSTKPARFMEFCGGHTVAIFRYGIRQLLPPHIEMLSGPGCPVCVTSTADLDKVIALSR
LPGVIICSFGDLLRVPSSRQSLLEVRAEGADVRIVYSTMDALEIARQNPLKKVIFVGIGFETTAPTIAASVIQARNQGLA
NYYVMSIHKITPPVMRAILDAGETRLSGIICPGHVSSITGSNAWEFIPEEYHLACAVSGFESLDILYCVKSLVDQVEDAT
PRLDVSYSRAVKPEGNTAALKIMDEVFDICPANWRGIGILPQSGLCLRPEFAAFDAEKNFEIKLSEPSRETPGCLCGEII
KGTRTPLECKLFSKVCTPENPVGPCMVSSEGTCAAYYHYGGKLG

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=40.8719346049046, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39724; Mature: 39724

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIEEFRSSQSGRTLLEYINKRSTKPARFMEFCGGHTVAIFRYGIRQLLPPHIEMLSGP
CCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHHHHCCHHHHHHCCC
GCPVCVTSTADLDKVIALSRLPGVIICSFGDLLRVPSSRQSLLEVRAEGADVRIVYSTMD
CCCEEEECCCCHHHHHHHHHCCCEEEECCHHHHCCCCHHHHHHHHHCCCCCEEEEEEHHH
ALEIARQNPLKKVIFVGIGFETTAPTIAASVIQARNQGLANYYVMSIHKITPPVMRAILD
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHH
AGETRLSGIICPGHVSSITGSNAWEFIPEEYHLACAVSGFESLDILYCVKSLVDQVEDAT
CCCHHHCEEECCCCCCCCCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
PRLDVSYSRAVKPEGNTAALKIMDEVFDICPANWRGIGILPQSGLCLRPEFAAFDAEKNF
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCHHHCCCCCCC
EIKLSEPSRETPGCLCGEIIKGTRTPLECKLFSKVCTPENPVGPCMVSSEGTCAAYYHYG
EEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECC
GKLG
CCCC
>Mature Secondary Structure
MNFIEEFRSSQSGRTLLEYINKRSTKPARFMEFCGGHTVAIFRYGIRQLLPPHIEMLSGP
CCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHHHHCCHHHHHHCCC
GCPVCVTSTADLDKVIALSRLPGVIICSFGDLLRVPSSRQSLLEVRAEGADVRIVYSTMD
CCCEEEECCCCHHHHHHHHHCCCEEEECCHHHHCCCCHHHHHHHHHCCCCCEEEEEEHHH
ALEIARQNPLKKVIFVGIGFETTAPTIAASVIQARNQGLANYYVMSIHKITPPVMRAILD
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHH
AGETRLSGIICPGHVSSITGSNAWEFIPEEYHLACAVSGFESLDILYCVKSLVDQVEDAT
CCCHHHCEEECCCCCCCCCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
PRLDVSYSRAVKPEGNTAALKIMDEVFDICPANWRGIGILPQSGLCLRPEFAAFDAEKNF
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCHHHCCCCCCC
EIKLSEPSRETPGCLCGEIIKGTRTPLECKLFSKVCTPENPVGPCMVSSEGTCAAYYHYG
EEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECC
GKLG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]