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The map label for this gene is hypE [H]

Identifier: 57233765

GI number: 57233765

Start: 1306024

End: 1307031

Strand: Direct

Name: hypE [H]

Synonym: DET1435

Alternate gene names: 57233765

Gene position: 1306024-1307031 (Clockwise)

Preceding gene: 57233766

Following gene: 57233764

Centisome position: 88.86

GC content: 54.17

Gene sequence:

>1008_bases
TTGGATAAAACCAAAATCCTGCTGGCCCACGGTTCGGGCGGGCGCTTAACCCATGACCTTATCACAAAGCACCTTGTCCA
GTCTCTGTCCAACCCGCTCCTAAACAAGCTGGATGATGCGGCTGTTTTTGAGTCCAAAGGGAAAACGGCTTTTACTACCG
ACAGTTACGTAGTAAACCCCATTTTCTTTCCCGGCGGCAATATAGGCAAGCTGGCAGTCTGCGGCACAGTCAATGACCTG
TCTGTTATGGGGGCTATACCCAAATACCTCAGCCTGGCTTTTATCATTGAAGAAGGCCTGGACATATCCGCTCTGGAAGA
AATAATAAAGTCTATCGCCGCTGCCGCTAAAGAAGCCGGGGTGGAAATAGTCACCGGAGACACCAAAGTGGTCAATACCG
GCAAAGCCGACAAGATATTTATAAATACCGCCGGGGTAGGCTTCATACCCGAAGGGCTGGACATATCCGGTGCAAACGCA
CGTCCGGATGATGCGGTAATTGTATCCGGCACTATGGGTGACCACGGCATAGCCATTATGGCCCAGAGGGAAGGGCTTAA
CTTTAAAACAGCCGTTGAAAGTGACTGCGCCCCCTTGAACGGGCTTATCACCGATATGCTCAAAGTCTGCCCCCGGATAC
ACGTCATGCGTGACCCCACCAGAGGCGGGCTGGCAACCACCCTTAACGAAATAGCCGGGCAGTCACAGGTGGGCATAGAA
CTTAACGAGGAGTCTATACCCGTCAAGCCGGCAGTGGGCGGTGCCTGTGAGGCACTCGGCCTTGACCCCCTGTATGTAGC
CAACGAGGGGAAAATTATAGCTATAATGCCGGAAAAAGATGCCCCGGCCGTACTCTCTGCCATGAAAGCTCACCCTTACG
GGAAAGACAGCGCCATTATCGGGCGGGTAATCTCCCCAAACCCCGGGCGGGTAAGCATACGCACCCCGCTGGGGGCGCTC
CGCATACTGGATATGCAAAGCGGAGAGCTGCTGCCGCGCATCTGCTGA

Upstream 100 bases:

>100_bases
AAGCTTTTTTCAAAGGTCTGCACCCCGGAAAACCCGGTCGGGCCGTGCATGGTCTCTTCCGAGGGCACCTGCGCCGCCTA
TTACCACTACGGAGGCAAAC

Downstream 100 bases:

>100_bases
ACTAACACCCCAAGCATTGACACAGGCTGGACAGTTATTCTGCCCGGCCTTTTTTATTTTCCCCAACCCCGAAATATCTT
TCAGGATGTATTGACAATGC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDKTKILLAHGSGGRLTHDLITKHLVQSLSNPLLNKLDDAAVFESKGKTAFTTDSYVVNPIFFPGGNIGKLAVCGTVNDL
SVMGAIPKYLSLAFIIEEGLDISALEEIIKSIAAAAKEAGVEIVTGDTKVVNTGKADKIFINTAGVGFIPEGLDISGANA
RPDDAVIVSGTMGDHGIAIMAQREGLNFKTAVESDCAPLNGLITDMLKVCPRIHVMRDPTRGGLATTLNEIAGQSQVGIE
LNEESIPVKPAVGGACEALGLDPLYVANEGKIIAIMPEKDAPAVLSAMKAHPYGKDSAIIGRVISPNPGRVSIRTPLGAL
RILDMQSGELLPRIC

Sequences:

>Translated_335_residues
MDKTKILLAHGSGGRLTHDLITKHLVQSLSNPLLNKLDDAAVFESKGKTAFTTDSYVVNPIFFPGGNIGKLAVCGTVNDL
SVMGAIPKYLSLAFIIEEGLDISALEEIIKSIAAAAKEAGVEIVTGDTKVVNTGKADKIFINTAGVGFIPEGLDISGANA
RPDDAVIVSGTMGDHGIAIMAQREGLNFKTAVESDCAPLNGLITDMLKVCPRIHVMRDPTRGGLATTLNEIAGQSQVGIE
LNEESIPVKPAVGGACEALGLDPLYVANEGKIIAIMPEKDAPAVLSAMKAHPYGKDSAIIGRVISPNPGRVSIRTPLGAL
RILDMQSGELLPRIC
>Mature_335_residues
MDKTKILLAHGSGGRLTHDLITKHLVQSLSNPLLNKLDDAAVFESKGKTAFTTDSYVVNPIFFPGGNIGKLAVCGTVNDL
SVMGAIPKYLSLAFIIEEGLDISALEEIIKSIAAAAKEAGVEIVTGDTKVVNTGKADKIFINTAGVGFIPEGLDISGANA
RPDDAVIVSGTMGDHGIAIMAQREGLNFKTAVESDCAPLNGLITDMLKVCPRIHVMRDPTRGGLATTLNEIAGQSQVGIE
LNEESIPVKPAVGGACEALGLDPLYVANEGKIIAIMPEKDAPAVLSAMKAHPYGKDSAIIGRVISPNPGRVSIRTPLGAL
RILDMQSGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=47.0414201183432, Blast_Score=299, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35052; Mature: 35052

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTKILLAHGSGGRLTHDLITKHLVQSLSNPLLNKLDDAAVFESKGKTAFTTDSYVVNP
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCEEEEE
IFFPGGNIGKLAVCGTVNDLSVMGAIPKYLSLAFIIEEGLDISALEEIIKSIAAAAKEAG
EEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VEIVTGDTKVVNTGKADKIFINTAGVGFIPEGLDISGANARPDDAVIVSGTMGDHGIAIM
EEEEECCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEE
AQREGLNFKTAVESDCAPLNGLITDMLKVCPRIHVMRDPTRGGLATTLNEIAGQSQVGIE
EECCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEECEE
LNEESIPVKPAVGGACEALGLDPLYVANEGKIIAIMPEKDAPAVLSAMKAHPYGKDSAII
ECCCCCCCCCCCCCCHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEE
GRVISPNPGRVSIRTPLGALRILDMQSGELLPRIC
EEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDKTKILLAHGSGGRLTHDLITKHLVQSLSNPLLNKLDDAAVFESKGKTAFTTDSYVVNP
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCEEEEE
IFFPGGNIGKLAVCGTVNDLSVMGAIPKYLSLAFIIEEGLDISALEEIIKSIAAAAKEAG
EEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VEIVTGDTKVVNTGKADKIFINTAGVGFIPEGLDISGANARPDDAVIVSGTMGDHGIAIM
EEEEECCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEE
AQREGLNFKTAVESDCAPLNGLITDMLKVCPRIHVMRDPTRGGLATTLNEIAGQSQVGIE
EECCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEECEE
LNEESIPVKPAVGGACEALGLDPLYVANEGKIIAIMPEKDAPAVLSAMKAHPYGKDSAII
ECCCCCCCCCCCCCCHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEE
GRVISPNPGRVSIRTPLGALRILDMQSGELLPRIC
EEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]