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The map label for this gene is perR [H]

Identifier: 57233643

GI number: 57233643

Start: 19041

End: 19469

Strand: Direct

Name: perR [H]

Synonym: DET0020

Alternate gene names: 57233643

Gene position: 19041-19469 (Clockwise)

Preceding gene: 57233644

Following gene: 57233641

Centisome position: 1.3

GC content: 48.25

Gene sequence:

>429_bases
ATGCATAAACAAAATTCTATAGCCGGTGAACTGGCAAATGACGGTTTTCGCCTGACCCCCCAGCGGGTGCTTATTCTGGA
AGCTCTGGATATGGCTGAAGGGCATATGAGCGCCGAAGATATCTACGCTGAGGTGGGGCAGGAATATCCCAATATAAATA
TTTCCACTGTTTACCGTACCCTGGAGCTTTTAAAGGGGCAAGGCCTGGTGCTGGAAACAGACATGGGTGACGGGCGTTTA
CGCTACCATAGTGTCAATAAGGGTTCACGCCATTATCTGGTTTGCCGTAAATGCGGAAAGATAACCGACCTGAGCGAAGA
TATGGTCAGAGAGCAGGAGCAGAGTATCTTAAAAAAGTATGGCTTTGCGGCTGATTTCAAAAATCTGGTTATTTACGGAC
AGTGCCGGAAGTGCGGTGATTCGGCCTGA

Upstream 100 bases:

>100_bases
GGTGACTATTATTCTGGACAGCCGTGACCGTTTGAACCCCCGCCAGTAGAGGCAGTTGCAAACAGTTGCAATAATAAGCT
CTAACTGCTAGACTAGCTGT

Downstream 100 bases:

>100_bases
GAGTTTGGGAGATTTTAGAGCAAATATATTCACTGCCTTTAAAAGGCGGTTTTTTTATTCGTGTATAACCGGGTTGGGGC
TGGGCTGGAAGGGGTGGGTG

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MHKQNSIAGELANDGFRLTPQRVLILEALDMAEGHMSAEDIYAEVGQEYPNINISTVYRTLELLKGQGLVLETDMGDGRL
RYHSVNKGSRHYLVCRKCGKITDLSEDMVREQEQSILKKYGFAADFKNLVIYGQCRKCGDSA

Sequences:

>Translated_142_residues
MHKQNSIAGELANDGFRLTPQRVLILEALDMAEGHMSAEDIYAEVGQEYPNINISTVYRTLELLKGQGLVLETDMGDGRL
RYHSVNKGSRHYLVCRKCGKITDLSEDMVREQEQSILKKYGFAADFKNLVIYGQCRKCGDSA
>Mature_142_residues
MHKQNSIAGELANDGFRLTPQRVLILEALDMAEGHMSAEDIYAEVGQEYPNINISTVYRTLELLKGQGLVLETDMGDGRL
RYHSVNKGSRHYLVCRKCGKITDLSEDMVREQEQSILKKYGFAADFKNLVIYGQCRKCGDSA

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=126, Percent_Identity=29.3650793650794, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15989; Mature: 15989

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKQNSIAGELANDGFRLTPQRVLILEALDMAEGHMSAEDIYAEVGQEYPNINISTVYRT
CCCCCCCCCHHCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHH
LELLKGQGLVLETDMGDGRLRYHSVNKGSRHYLVCRKCGKITDLSEDMVREQEQSILKKY
HHHHCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
GFAADFKNLVIYGQCRKCGDSA
CCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MHKQNSIAGELANDGFRLTPQRVLILEALDMAEGHMSAEDIYAEVGQEYPNINISTVYRT
CCCCCCCCCHHCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHH
LELLKGQGLVLETDMGDGRLRYHSVNKGSRHYLVCRKCGKITDLSEDMVREQEQSILKKY
HHHHCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
GFAADFKNLVIYGQCRKCGDSA
CCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA