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The map label for this gene is dhaL [H]

Identifier: 38234869

GI number: 38234869

Start: 2441684

End: 2442325

Strand: Direct

Name: dhaL [H]

Synonym: DIP2335

Alternate gene names: 38234869

Gene position: 2441684-2442325 (Clockwise)

Preceding gene: 38234868

Following gene: 38234870

Centisome position: 98.11

GC content: 63.55

Gene sequence:

>642_bases
ATGGTTTTGGATACTCAATGGGCTTTGGCGTGGATTCGCGGTTGCGCGCGGTTGGCTTCTGAGCACCGTGAGGAGCTGAT
TGATTTGGATCGTGCGATTGGCGATGCTGATCATGGTGAAAACGTTGACCGCGGGTTTGCGGCGGTCGTCGCAAAGCTTG
ATGACCTGCCGGAAAGCGCCACCTCGGCGGATATTCTGAAGGTGACTGCACAGACGTTGATTTCTACTGTTGGCGGCGCG
TCGGGCCCGTTGTTGGGCACGGCGTTTCTGCGTGCGTCTAAGGCGCTGACCGCGCCGACTATCGACGCCTCCTCCGCCGC
CGCTCTCATCGCCGCAGCCTTGGAGGGCATTCAGGCCCGCGGCAAGGCTAGCGAGGGGGAGAAGACGATGGTTGATGCGT
GGGCGCCGGCTGCACATGCGGCCGCTACCGCCGCCGACGAGGGTGCAAGCCCTGCGGGTGTGTTGGCGCGCGCTGCGGCT
GCCGCAGCTCAGGGTGCGGCCGATACTGAGCCAATGGTAGCAACCAAGGGGCGCGCTTCTTACCTTGGGGAGCGTTCTGT
TGGCCACCGCGATCCGGGCGCTACGTCCTCTGCTTATTTCTTGCAGGCGGCTGCTGACGCCGCTTCCGAGGGGACTGCAT
GA

Upstream 100 bases:

>100_bases
GCAGGGGGCGTCGGTGACGTTGATGCGGGTGTCTGATGAGTTGCTTGAGCTTTTCGACGCCCCGGTTAATACTGTGGCTT
TGAGGAAGGGAATGTAGATC

Downstream 100 bases:

>100_bases
GCGCTGTAGGTTTGGTTTTGGTTTCTCATTCCCAGAAGCTTGCCGAGGGGTTGGCGGATTTGGCTGCCCAGATGGCTGGA
GATGTTCACATTGTGTCTGC

Product: putative dihydroxyacetone kinase sununit

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MVLDTQWALAWIRGCARLASEHREELIDLDRAIGDADHGENVDRGFAAVVAKLDDLPESATSADILKVTAQTLISTVGGA
SGPLLGTAFLRASKALTAPTIDASSAAALIAAALEGIQARGKASEGEKTMVDAWAPAAHAAATAADEGASPAGVLARAAA
AAAQGAADTEPMVATKGRASYLGERSVGHRDPGATSSAYFLQAAADAASEGTA

Sequences:

>Translated_213_residues
MVLDTQWALAWIRGCARLASEHREELIDLDRAIGDADHGENVDRGFAAVVAKLDDLPESATSADILKVTAQTLISTVGGA
SGPLLGTAFLRASKALTAPTIDASSAAALIAAALEGIQARGKASEGEKTMVDAWAPAAHAAATAADEGASPAGVLARAAA
AAAQGAADTEPMVATKGRASYLGERSVGHRDPGATSSAYFLQAAADAASEGTA
>Mature_213_residues
MVLDTQWALAWIRGCARLASEHREELIDLDRAIGDADHGENVDRGFAAVVAKLDDLPESATSADILKVTAQTLISTVGGA
SGPLLGTAFLRASKALTAPTIDASSAAALIAAALEGIQARGKASEGEKTMVDAWAPAAHAAATAADEGASPAGVLARAAA
AAAQGAADTEPMVATKGRASYLGERSVGHRDPGATSSAYFLQAAADAASEGTA

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=189, Percent_Identity=35.4497354497354, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787449, Length=211, Percent_Identity=43.1279620853081, Blast_Score=159, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323570, Length=204, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 21307; Mature: 21307

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDTQWALAWIRGCARLASEHREELIDLDRAIGDADHGENVDRGFAAVVAKLDDLPESA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
TSADILKVTAQTLISTVGGASGPLLGTAFLRASKALTAPTIDASSAAALIAAALEGIQAR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
GKASEGEKTMVDAWAPAAHAAATAADEGASPAGVLARAAAAAAQGAADTEPMVATKGRAS
CCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCHHH
YLGERSVGHRDPGATSSAYFLQAAADAASEGTA
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVLDTQWALAWIRGCARLASEHREELIDLDRAIGDADHGENVDRGFAAVVAKLDDLPESA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
TSADILKVTAQTLISTVGGASGPLLGTAFLRASKALTAPTIDASSAAALIAAALEGIQAR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
GKASEGEKTMVDAWAPAAHAAATAADEGASPAGVLARAAAAAAQGAADTEPMVATKGRAS
CCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCHHH
YLGERSVGHRDPGATSSAYFLQAAADAASEGTA
HHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]