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The map label for this gene is pgm [H]

Identifier: 38234452

GI number: 38234452

Start: 1924981

End: 1926618

Strand: Reverse

Name: pgm [H]

Synonym: DIP1882

Alternate gene names: 38234452

Gene position: 1926618-1924981 (Counterclockwise)

Preceding gene: 38234455

Following gene: 38234451

Centisome position: 77.42

GC content: 57.08

Gene sequence:

>1638_bases
ATGGCACACGAACGAGCAGGTCAACTTGCGCAGCCTCAGGACCTCATTGACATCGCTGAGGTGGTTACCGCCTATTACAC
GCGGACCCCAGACGCGGATAACCCAGATCAGCAGGTGGCTTTTGGTACGTCGGGCCACCGCGGTTCTTCGCTGGACACGG
CCTTCAATGAGAATCACATTCTTGCTATCACTCAAGCGATCGTGGAGTACCGTGCGCAGCATCACATTGGTGGTCCGATC
TTTATTGGCCGCGACACCCATGCGTTGAGCGAGCCCGCGATGATTTCTGCCCTTGAGGTGCTGTTGGCACATGGTATCGA
GGTGCTTGTCGACGACCGCGGCCGCTACACCCCAACGCCAGCTGTCTCTCACGCGATCTTGGCGTACAACGCGCAGCGCA
GCGACTCGTCACAGTATTCCGATGGCATCGTGATTACGCCTTCGCACAATCCGCCTCGTGATGGTGGCTTTAAGTACAAC
CCACCCAACGGCGGACCTGCAGATACAGATGCTACCGATTGGATTGCAGATCGTGCCAACACCTTGCTGCGTGAGGGGCT
TGTTTCTGTGAAACGCACCTCGGTTACAGGTGTGCTCGACCCACGGGCGCATCGTCACAACTACATGGAAAATTACATTG
CTGACCTGCCCAATGTGGTGGACATCGATGCGATTCGAAATTCGGGATTGGCTATTGGTGCCGATCCTATGGGTGGCGCT
TCGGTGGACTATTGGGGTGCGATTGCAGAGAAGCATTCGCTTAACCTCACTGTGGTTAACCCGCTTGTCGACGCCACCTG
GCGTTTCATGACACTCGATACCGATGGCAAGATCCGCATGGACTGCTCGTCGCCAGACTCGATGGCCTCGCTGGTGCATA
ACCGCACGAAGTATGACATCGCTACGGGTAACGATGCCGATGCTGATCGCCACGGCATTGTCACACCTGATGCGGGACTG
ATGAACCCTAACCATTACCTCGCCGTGGCCATCGACTACTTGTTCTCGCACCGCCCGCAGTGGAATTCTTCCACAGCAGT
GGGCAAGACCTTGGTCAGTTCCTCGATGATTGACCGTGTGGTGGCCGATCTTGGTCGCAAGTTGGTGGAGGTGCCTGTGG
GCTTTAAGTGGTTCGTCCCAGGGCTTGTCGACGGCTCCGTGGGGTTCGGCGGCGAGGAATCCGCTGGCGCATCCTTCCTT
CGACACAATGGCACCGTATGGTCGACTGACAAAGACGGCATTATCTTGGATCTGCTTGCCTCGGAAATCACAGCAGTGAC
CGGAAAAACTCCGTCGCAACGCTACGAAGAGCTTGCTGCCCGCTTTGGCTCCCCTGCCTATGCGCGCACTGATGCGCCAG
CTACCCGTGAGCAAAAGGCGGTGCTCAAGAAGCTCTCGCCTGAGCAGGTTACAGCCACCGAACTTGCCGGTGAGGCGATT
ACCGCGAAGCTCACCACTGCTCCTGGCAACGGCGCTGCTATCGGCGGACTGAAGGTGACTACTGAAAACGCGTGGTTTGC
TGCGCGCCCATCCGGAACTGAGGATAAGTACAAGATCTACGCGGAGTCCTTCCTCGGAGCGGACCACCTCGCGATGGTAC
AGCGTGAAGCACAGAATCTCGTTTCTGATGTTTTGTGA

Upstream 100 bases:

>100_bases
AAACCAGCACCGAGTCCTACTAAAACGCCCTGCATGGGTTGTGATTTTACTACGATGGTAGGCGTTAAGACTTTCGACTA
TGCGTTGCAGGAGCAGCTTC

Downstream 100 bases:

>100_bases
TTAGACTGGCCAAGGTGACTGAAACTTCAAAGAAGCGAGTGTCTTTACACCTTGTGCTTGACTGCATAAGCGCCTTCGCA
CGGTTCTTCATGGCATATAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MAHERAGQLAQPQDLIDIAEVVTAYYTRTPDADNPDQQVAFGTSGHRGSSLDTAFNENHILAITQAIVEYRAQHHIGGPI
FIGRDTHALSEPAMISALEVLLAHGIEVLVDDRGRYTPTPAVSHAILAYNAQRSDSSQYSDGIVITPSHNPPRDGGFKYN
PPNGGPADTDATDWIADRANTLLREGLVSVKRTSVTGVLDPRAHRHNYMENYIADLPNVVDIDAIRNSGLAIGADPMGGA
SVDYWGAIAEKHSLNLTVVNPLVDATWRFMTLDTDGKIRMDCSSPDSMASLVHNRTKYDIATGNDADADRHGIVTPDAGL
MNPNHYLAVAIDYLFSHRPQWNSSTAVGKTLVSSSMIDRVVADLGRKLVEVPVGFKWFVPGLVDGSVGFGGEESAGASFL
RHNGTVWSTDKDGIILDLLASEITAVTGKTPSQRYEELAARFGSPAYARTDAPATREQKAVLKKLSPEQVTATELAGEAI
TAKLTTAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFLGADHLAMVQREAQNLVSDVL

Sequences:

>Translated_545_residues
MAHERAGQLAQPQDLIDIAEVVTAYYTRTPDADNPDQQVAFGTSGHRGSSLDTAFNENHILAITQAIVEYRAQHHIGGPI
FIGRDTHALSEPAMISALEVLLAHGIEVLVDDRGRYTPTPAVSHAILAYNAQRSDSSQYSDGIVITPSHNPPRDGGFKYN
PPNGGPADTDATDWIADRANTLLREGLVSVKRTSVTGVLDPRAHRHNYMENYIADLPNVVDIDAIRNSGLAIGADPMGGA
SVDYWGAIAEKHSLNLTVVNPLVDATWRFMTLDTDGKIRMDCSSPDSMASLVHNRTKYDIATGNDADADRHGIVTPDAGL
MNPNHYLAVAIDYLFSHRPQWNSSTAVGKTLVSSSMIDRVVADLGRKLVEVPVGFKWFVPGLVDGSVGFGGEESAGASFL
RHNGTVWSTDKDGIILDLLASEITAVTGKTPSQRYEELAARFGSPAYARTDAPATREQKAVLKKLSPEQVTATELAGEAI
TAKLTTAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFLGADHLAMVQREAQNLVSDVL
>Mature_544_residues
AHERAGQLAQPQDLIDIAEVVTAYYTRTPDADNPDQQVAFGTSGHRGSSLDTAFNENHILAITQAIVEYRAQHHIGGPIF
IGRDTHALSEPAMISALEVLLAHGIEVLVDDRGRYTPTPAVSHAILAYNAQRSDSSQYSDGIVITPSHNPPRDGGFKYNP
PNGGPADTDATDWIADRANTLLREGLVSVKRTSVTGVLDPRAHRHNYMENYIADLPNVVDIDAIRNSGLAIGADPMGGAS
VDYWGAIAEKHSLNLTVVNPLVDATWRFMTLDTDGKIRMDCSSPDSMASLVHNRTKYDIATGNDADADRHGIVTPDAGLM
NPNHYLAVAIDYLFSHRPQWNSSTAVGKTLVSSSMIDRVVADLGRKLVEVPVGFKWFVPGLVDGSVGFGGEESAGASFLR
HNGTVWSTDKDGIILDLLASEITAVTGKTPSQRYEELAARFGSPAYARTDAPATREQKAVLKKLSPEQVTATELAGEAIT
AKLTTAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFLGADHLAMVQREAQNLVSDVL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=400, Percent_Identity=27, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786904, Length=544, Percent_Identity=62.5, Blast_Score=680, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=403, Percent_Identity=25.3101736972705, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322722, Length=408, Percent_Identity=25.9803921568627, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17864244, Length=474, Percent_Identity=26.5822784810127, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58548; Mature: 58417

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHERAGQLAQPQDLIDIAEVVTAYYTRTPDADNPDQQVAFGTSGHRGSSLDTAFNENHI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
LAITQAIVEYRAQHHIGGPIFIGRDTHALSEPAMISALEVLLAHGIEVLVDDRGRYTPTP
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCH
AVSHAILAYNAQRSDSSQYSDGIVITPSHNPPRDGGFKYNPPNGGPADTDATDWIADRAN
HHHHEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHH
TLLREGLVSVKRTSVTGVLDPRAHRHNYMENYIADLPNVVDIDAIRNSGLAIGADPMGGA
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCEEECCCCCCC
SVDYWGAIAEKHSLNLTVVNPLVDATWRFMTLDTDGKIRMDCSSPDSMASLVHNRTKYDI
CCHHHHHHHHCCCCEEEEECCHHCCCEEEEEECCCCCEEEECCCCHHHHHHHHCCCEEEE
ATGNDADADRHGIVTPDAGLMNPNHYLAVAIDYLFSHRPQWNSSTAVGKTLVSSSMIDRV
ECCCCCCCCCCCCCCCCCCCCCCCCEEEHEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VADLGRKLVEVPVGFKWFVPGLVDGSVGFGGEESAGASFLRHNGTVWSTDKDGIILDLLA
HHHHHHHHHHCCCCCEEECCCEECCCCCCCCCCCCCHHHHHCCCEEEECCCCCEEHHHHH
SEITAVTGKTPSQRYEELAARFGSPAYARTDAPATREQKAVLKKLSPEQVTATELAGEAI
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEE
TAKLTTAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFLGADHLAMVQREAQNL
EEEEEECCCCCEEECCEEEEECCCEEEECCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHH
VSDVL
HHHCC
>Mature Secondary Structure 
AHERAGQLAQPQDLIDIAEVVTAYYTRTPDADNPDQQVAFGTSGHRGSSLDTAFNENHI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
LAITQAIVEYRAQHHIGGPIFIGRDTHALSEPAMISALEVLLAHGIEVLVDDRGRYTPTP
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCH
AVSHAILAYNAQRSDSSQYSDGIVITPSHNPPRDGGFKYNPPNGGPADTDATDWIADRAN
HHHHEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHH
TLLREGLVSVKRTSVTGVLDPRAHRHNYMENYIADLPNVVDIDAIRNSGLAIGADPMGGA
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCEEECCCCCCC
SVDYWGAIAEKHSLNLTVVNPLVDATWRFMTLDTDGKIRMDCSSPDSMASLVHNRTKYDI
CCHHHHHHHHCCCCEEEEECCHHCCCEEEEEECCCCCEEEECCCCHHHHHHHHCCCEEEE
ATGNDADADRHGIVTPDAGLMNPNHYLAVAIDYLFSHRPQWNSSTAVGKTLVSSSMIDRV
ECCCCCCCCCCCCCCCCCCCCCCCCEEEHEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VADLGRKLVEVPVGFKWFVPGLVDGSVGFGGEESAGASFLRHNGTVWSTDKDGIILDLLA
HHHHHHHHHHCCCCCEEECCCEECCCCCCCCCCCCCHHHHHCCCEEEECCCCCEEHHHHH
SEITAVTGKTPSQRYEELAARFGSPAYARTDAPATREQKAVLKKLSPEQVTATELAGEAI
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEE
TAKLTTAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFLGADHLAMVQREAQNL
EEEEEECCCCCEEECCEEEEECCCEEEECCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHH
VSDVL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]