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The map label for this gene is ctaD

Identifier: 38234434

GI number: 38234434

Start: 1907448

End: 1909142

Strand: Reverse

Name: ctaD

Synonym: DIP1864

Alternate gene names: 38234434

Gene position: 1909142-1907448 (Counterclockwise)

Preceding gene: 38234435

Following gene: 38234433

Centisome position: 76.71

GC content: 55.4

Gene sequence:

>1695_bases
ATGACCGCTGTGGCGCCGAGGCTCGAAAATTATGCCGAGCCAACAAGGCCCGCACCAACCGGTGGTGCCCGCAAGGGAAC
GCTGGCGTGGAAGATGCTGACCACAACTGACCACAAACTACTGGGCATGATGTACATCGTCATGTCCTTCGTGTGGTTCT
TCGTTGGTGGTTTGATGGCTCTGCTTATTCGTGCCGAGCTCTTCAGCCCAGGACTTCAGTTTCTGTCTAACGAGCAGTTC
AACCAGCTGTTCACCCTTCATGGAACAATCATGCTGCTGGCCTTTGGTACGCCAGTGGTGTGGGGCTTTTCTAACTATAT
TCTGCCATTGCAGATCGGCGCACCTGACGTGGCATTCCCACGTTTGAACGCTTTTGGTTTCTGGATTACCCAGATCGGCG
TCGTCGCAATGCTGGCAGGCTTCCTCACCCCAGGTGGCGCAGCAGACTTCGGCTGGACAATGTACCTGCCTTTGGCTGAC
TCCATCCACTCCCCAGGTGTGGGCGGCGACTTCTGGATCATCGGCGTGGGGGCAACAGGTGTCGGCACCATTGCTTCCGC
CGTGAACATGATCACCACCATCCTGTGCATGCGTGCACCAGGTATGACCATGTTCCGTATGCCAATTTTCTGCTGGAACA
TCTTCGTTGCTTCCGTCATCGTTCTTCTGATCTTCCCACTGCTCACCGCAGCAGCTTTGGGTGTTATGTACGACCGCAAG
CTCGGTGGACACATCTACGATCCAGGTAACGGCGGTGCCATCCTGTGGCAGCACCTCTTCTGGTTCTTCGGCCACCCAGA
GGTGTACGTCCTAGCACTGCCATTCTTCGGCATCGTTTCCGAGGTCATCCCAGTGTTCGCACGTAAGCCAATGTTCGGCT
ACATCGGTCTGGTTTTCGCAACCTTGTCCATCGGTATGCTTTCGATGGCTGTGTGGGCACACCACATGTTCGTTACCGGC
GCAATCCTGTTGCCATTCTTCTCCTTCATGACGTTCCTCATCTCGGTTCCAACCGGTGTGAAGTTCTTCAACTGGTTGGG
CACCATGTGGCGCGGTCACATCTCTTGGGAAACCCCGATGACTTGGACCATGGGCTTCTTGGTGACGTTCCTCTTCGGTG
GTCTGACCGGTATTATGCTGGCATCCCCACCACTGGACTTCCACATCTCTGACACCTACTTCGTGGTTGCACACTTCCAC
TACACCCTCTTCGGTACCGTGGTATTTGCTTCCTACGCTGGTGTGTACTTCTGGTTCCCCAAGATGACCGGCCGTATGTT
GGATGAGCGTCTGGGCAAGATCCACTTCTGGATCACCTTCGTTGGCTTCCATGGCACCTTCTTGGTTCAGCACTGGGTTG
GTAACGAGGGCATGCCACGTCGTTACGCTGACTACCTCGAGTCTGACGGATTCACCACCTTGAACCAGATTTCTACCGTG
TTCTCCTTCTTGCTTGGTGTCTCGGTTATCCCATTCATCTGGAACGTGTTCAAGTCCTACCGCTACGGTGAGATCGTTAC
TGTCGACGACCCATGGGGTTATGGCAACTCCTTGGAGTGGGCTACCTCTTGCCCTCCTCCACGCCACAACTTCACGTCGC
TGCCACGTATCCGCTCCGAGCGTCCTGCCTTCGAGCTGCACTACCCACACATGGTGGAGCGCATGCGCCGCGAGGCTCAC
ATTGGACACCACTGA

Upstream 100 bases:

>100_bases
GGCTGGATTAGTGCCATAGCCTGCCATAAGATGTCACAGTGTAAATCTGGTCACCTCATACCCGCCGTGGTATGAGGTAC
CCACAAGTCAGGAGGATCGT

Downstream 100 bases:

>100_bases
GCCAGTGAACAAGCGATAATCTGATCGCTTTCTGACTTTGAACGAGGACCTAAGTTTTCCTAGGTCCTCGTTTTTGTGTT
ACCTAGTACAGGGGTGTTAA

Product: cytochrome C oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MTAVAPRLENYAEPTRPAPTGGARKGTLAWKMLTTTDHKLLGMMYIVMSFVWFFVGGLMALLIRAELFSPGLQFLSNEQF
NQLFTLHGTIMLLAFGTPVVWGFSNYILPLQIGAPDVAFPRLNAFGFWITQIGVVAMLAGFLTPGGAADFGWTMYLPLAD
SIHSPGVGGDFWIIGVGATGVGTIASAVNMITTILCMRAPGMTMFRMPIFCWNIFVASVIVLLIFPLLTAAALGVMYDRK
LGGHIYDPGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVIPVFARKPMFGYIGLVFATLSIGMLSMAVWAHHMFVTG
AILLPFFSFMTFLISVPTGVKFFNWLGTMWRGHISWETPMTWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFH
YTLFGTVVFASYAGVYFWFPKMTGRMLDERLGKIHFWITFVGFHGTFLVQHWVGNEGMPRRYADYLESDGFTTLNQISTV
FSFLLGVSVIPFIWNVFKSYRYGEIVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSERPAFELHYPHMVERMRREAH
IGHH

Sequences:

>Translated_564_residues
MTAVAPRLENYAEPTRPAPTGGARKGTLAWKMLTTTDHKLLGMMYIVMSFVWFFVGGLMALLIRAELFSPGLQFLSNEQF
NQLFTLHGTIMLLAFGTPVVWGFSNYILPLQIGAPDVAFPRLNAFGFWITQIGVVAMLAGFLTPGGAADFGWTMYLPLAD
SIHSPGVGGDFWIIGVGATGVGTIASAVNMITTILCMRAPGMTMFRMPIFCWNIFVASVIVLLIFPLLTAAALGVMYDRK
LGGHIYDPGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVIPVFARKPMFGYIGLVFATLSIGMLSMAVWAHHMFVTG
AILLPFFSFMTFLISVPTGVKFFNWLGTMWRGHISWETPMTWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFH
YTLFGTVVFASYAGVYFWFPKMTGRMLDERLGKIHFWITFVGFHGTFLVQHWVGNEGMPRRYADYLESDGFTTLNQISTV
FSFLLGVSVIPFIWNVFKSYRYGEIVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSERPAFELHYPHMVERMRREAH
IGHH
>Mature_563_residues
TAVAPRLENYAEPTRPAPTGGARKGTLAWKMLTTTDHKLLGMMYIVMSFVWFFVGGLMALLIRAELFSPGLQFLSNEQFN
QLFTLHGTIMLLAFGTPVVWGFSNYILPLQIGAPDVAFPRLNAFGFWITQIGVVAMLAGFLTPGGAADFGWTMYLPLADS
IHSPGVGGDFWIIGVGATGVGTIASAVNMITTILCMRAPGMTMFRMPIFCWNIFVASVIVLLIFPLLTAAALGVMYDRKL
GGHIYDPGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVIPVFARKPMFGYIGLVFATLSIGMLSMAVWAHHMFVTGA
ILLPFFSFMTFLISVPTGVKFFNWLGTMWRGHISWETPMTWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFHY
TLFGTVVFASYAGVYFWFPKMTGRMLDERLGKIHFWITFVGFHGTFLVQHWVGNEGMPRRYADYLESDGFTTLNQISTVF
SFLLGVSVIPFIWNVFKSYRYGEIVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSERPAFELHYPHMVERMRREAHI
GHH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=41.9729206963249, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=529, Percent_Identity=42.7221172022684, Blast_Score=390, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226519, Length=533, Percent_Identity=37.3358348968105, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6226524, Length=320, Percent_Identity=40, Blast_Score=234, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=34.9593495934959, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX1_CORDI (Q6NFM3)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940201.1
- ProteinModelPortal:   Q6NFM3
- SMR:   Q6NFM3
- GeneID:   2649239
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1864
- NMPDR:   fig|257309.1.peg.1792
- HOGENOM:   HBG603668
- OMA:   AFGFWIT
- PhylomeDB:   Q6NFM3
- ProtClustDB:   CLSK2519649
- BioCyc:   CDIP257309:DIP1864-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR000883
- InterPro:   IPR014241
- Gene3D:   G3DSA:1.20.210.10
- PANTHER:   PTHR10422
- PRINTS:   PR01165
- TIGRFAMs:   TIGR02891

Pfam domain/function: PF00115 COX1; SSF81442 COX1

EC number: =1.9.3.1

Molecular weight: Translated: 63292; Mature: 63161

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50855 COX1; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4521c718)-; HASH(0x4538a844)-; HASH(0x452bd014)-; HASH(0xcee2fdc)-; HASH(0xd4fa718)-; HASH(0x453ad0d4)-; HASH(0x452d982c)-; HASH(0x4520e114)-; HASH(0x452c8c90)-; HASH(0xd7dd7c8)-; HASH(0x453a6030)-; HASH(0x45228bec)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAPRLENYAEPTRPAPTGGARKGTLAWKMLTTTDHKLLGMMYIVMSFVWFFVGGLMA
CCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFSPGLQFLSNEQFNQLFTLHGTIMLLAFGTPVVWGFSNYILPLQIGAPDVAFP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCEECCCCCEEEEEECCCCCCCC
RLNAFGFWITQIGVVAMLAGFLTPGGAADFGWTMYLPLADSIHSPGVGGDFWIIGVGATG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHCCCCCCCCCCEEEEEECCCC
VGTIASAVNMITTILCMRAPGMTMFRMPIFCWNIFVASVIVLLIFPLLTAAALGVMYDRK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDPGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVIPVFARKPMFGYIGLVFA
CCCEEECCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TLSIGMLSMAVWAHHMFVTGAILLPFFSFMTFLISVPTGVKFFNWLGTMWRGHISWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
TWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFHYTLFGTVVFASYAGVYFWFP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHCCCEEEHH
KMTGRMLDERLGKIHFWITFVGFHGTFLVQHWVGNEGMPRRYADYLESDGFTTLNQISTV
HHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHH
FSFLLGVSVIPFIWNVFKSYRYGEIVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMVERMRREAHIGHH
CCCEEECCHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
TAVAPRLENYAEPTRPAPTGGARKGTLAWKMLTTTDHKLLGMMYIVMSFVWFFVGGLMA
CCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFSPGLQFLSNEQFNQLFTLHGTIMLLAFGTPVVWGFSNYILPLQIGAPDVAFP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCEECCCCCEEEEEECCCCCCCC
RLNAFGFWITQIGVVAMLAGFLTPGGAADFGWTMYLPLADSIHSPGVGGDFWIIGVGATG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHCCCCCCCCCCEEEEEECCCC
VGTIASAVNMITTILCMRAPGMTMFRMPIFCWNIFVASVIVLLIFPLLTAAALGVMYDRK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDPGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVIPVFARKPMFGYIGLVFA
CCCEEECCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TLSIGMLSMAVWAHHMFVTGAILLPFFSFMTFLISVPTGVKFFNWLGTMWRGHISWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
TWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFHYTLFGTVVFASYAGVYFWFP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHCCCEEEHH
KMTGRMLDERLGKIHFWITFVGFHGTFLVQHWVGNEGMPRRYADYLESDGFTTLNQISTV
HHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHH
FSFLLGVSVIPFIWNVFKSYRYGEIVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMVERMRREAHIGHH
CCCEEECCHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14602910