Click here to switch to the map view.

The map label for this gene is nrdF [H]

Identifier: 38234435

GI number: 38234435

Start: 1909504

End: 1910490

Strand: Reverse

Name: nrdF [H]

Synonym: DIP1865

Alternate gene names: 38234435

Gene position: 1910490-1909504 (Counterclockwise)

Preceding gene: 38234437

Following gene: 38234434

Centisome position: 76.77

GC content: 50.35

Gene sequence:

>987_bases
GTGACTACGTACAACGCATACTTTGAATCTCATCCAAATCCGGTAGCGGCTATTAACTGGAACTCCATTCCAGATGAGAA
GGATCTTGAAGTTTGGGATCGTCTGACCGGTAACTTCTGGCTTCCAGAAAAAATCCCAGTATCTAACGACATTAAGAGCT
GGAACACCCTTAATGATCTGGAAAAGCAAACCACCATGCGCGTGTTCACTGGCCTGACATTGCTGGATACTATTCAGGGA
ACCGTTGGCGCTGTGTCGATGCTTCCGGATGCCGTGTCTCTTCATGAGGAGGCCGTGTATACAAACATTGCCTTCATGGA
AAGCGTTCACGCAAAGAGCTATTCCAATATCTTTATGACTCTTGCGTCCACGCCAGAAATTAACGACGCCTTCCGCTGGT
CTGAGGAAAACGAAAACCTGCAGAAGAAAGCGAAGATCATCCTCTCTTACTACGAGGGCGACGATCCGCTGAAGCGCAAG
GTTGCATCCACCTTGTTGGAGTCCTTCCTGTTCTACTCCGGCTTCTATCTTCCAATGTATTGGTCGAGCCACGCCAAGCT
CACCAATACCGCGGACATTATTCGCTTGATTATTCGCGATGAAGCGGTCCATGGCTATTACATTGGCTATAAGTTCCAGC
AGGCGCTGCGTAAGGAAACTCCAGAACGCCAGGCGGAGCTGAAGGGGTACACCTTCGACTTGCTTTACGATCTCTATGAC
AATGAGATCCAGTACACCGAAGACTTGTATGACGATCTTGGCTGGACCGAAGACGTCAAGCGCTTCCTGCGGTACAACGC
AAACAAGGCGTTGAACAACTTGGGTTACGAGGCACTGTTCCCGGCGGACGAGTGCCGTGTTTCGCCAGCAATTCTTTCTG
CGCTGTCGCCGAACGCTGATGAGAATCACGACTTCTTCTCAGGGTCCGGTTCTTCCTACGTGATCGGCAAGGCTGAGAAC
ACCACGGACGACGACTGGGATTTCTAA

Upstream 100 bases:

>100_bases
CAAACCAAACCACCGACCATAAAGTGTGCCGAAAGTCACATTTTGGGTCGGTGGTGTAAGCTCAAAAAGACTTGCCAAAA
AAAGGAGTGTGTAACAACCT

Downstream 100 bases:

>100_bases
TTCCATGAAAACCGCTGTGCAACTAATTTAGTTGTGCAGCGGTTTTCTTTGTTCAACCTTTAGGTTGATCGCGGGTGGGG
GTGAAATCAGGGTCACATTG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTTYNAYFESHPNPVAAINWNSIPDEKDLEVWDRLTGNFWLPEKIPVSNDIKSWNTLNDLEKQTTMRVFTGLTLLDTIQG
TVGAVSMLPDAVSLHEEAVYTNIAFMESVHAKSYSNIFMTLASTPEINDAFRWSEENENLQKKAKIILSYYEGDDPLKRK
VASTLLESFLFYSGFYLPMYWSSHAKLTNTADIIRLIIRDEAVHGYYIGYKFQQALRKETPERQAELKGYTFDLLYDLYD
NEIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEALFPADECRVSPAILSALSPNADENHDFFSGSGSSYVIGKAEN
TTDDDWDF

Sequences:

>Translated_328_residues
MTTYNAYFESHPNPVAAINWNSIPDEKDLEVWDRLTGNFWLPEKIPVSNDIKSWNTLNDLEKQTTMRVFTGLTLLDTIQG
TVGAVSMLPDAVSLHEEAVYTNIAFMESVHAKSYSNIFMTLASTPEINDAFRWSEENENLQKKAKIILSYYEGDDPLKRK
VASTLLESFLFYSGFYLPMYWSSHAKLTNTADIIRLIIRDEAVHGYYIGYKFQQALRKETPERQAELKGYTFDLLYDLYD
NEIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEALFPADECRVSPAILSALSPNADENHDFFSGSGSSYVIGKAEN
TTDDDWDF
>Mature_327_residues
TTYNAYFESHPNPVAAINWNSIPDEKDLEVWDRLTGNFWLPEKIPVSNDIKSWNTLNDLEKQTTMRVFTGLTLLDTIQGT
VGAVSMLPDAVSLHEEAVYTNIAFMESVHAKSYSNIFMTLASTPEINDAFRWSEENENLQKKAKIILSYYEGDDPLKRKV
ASTLLESFLFYSGFYLPMYWSSHAKLTNTADIIRLIIRDEAVHGYYIGYKFQQALRKETPERQAELKGYTFDLLYDLYDN
EIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEALFPADECRVSPAILSALSPNADENHDFFSGSGSSYVIGKAENT
TDDDWDF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=314, Percent_Identity=67.515923566879, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1788567, Length=359, Percent_Identity=24.7910863509749, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 37675; Mature: 37544

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYNAYFESHPNPVAAINWNSIPDEKDLEVWDRLTGNFWLPEKIPVSNDIKSWNTLNDL
CCCCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
EKQTTMRVFTGLTLLDTIQGTVGAVSMLPDAVSLHEEAVYTNIAFMESVHAKSYSNIFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LASTPEINDAFRWSEENENLQKKAKIILSYYEGDDPLKRKVASTLLESFLFYSGFYLPMY
ECCCCCCCHHHCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEE
WSSHAKLTNTADIIRLIIRDEAVHGYYIGYKFQQALRKETPERQAELKGYTFDLLYDLYD
ECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHC
NEIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEALFPADECRVSPAILSALSPNAD
CCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHCCCCEECCHHHHHCCHHHHHHHCCCCC
ENHDFFSGSGSSYVIGKAENTTDDDWDF
CCCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TTYNAYFESHPNPVAAINWNSIPDEKDLEVWDRLTGNFWLPEKIPVSNDIKSWNTLNDL
CCCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
EKQTTMRVFTGLTLLDTIQGTVGAVSMLPDAVSLHEEAVYTNIAFMESVHAKSYSNIFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LASTPEINDAFRWSEENENLQKKAKIILSYYEGDDPLKRKVASTLLESFLFYSGFYLPMY
ECCCCCCCHHHCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEE
WSSHAKLTNTADIIRLIIRDEAVHGYYIGYKFQQALRKETPERQAELKGYTFDLLYDLYD
ECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHC
NEIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEALFPADECRVSPAILSALSPNAD
CCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHCCCCEECCHHHHHCCHHHHHHHCCCCC
ENHDFFSGSGSSYVIGKAENTTDDDWDF
CCCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]