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The map label for this gene is pncA [C]

Identifier: 38234410

GI number: 38234410

Start: 1881693

End: 1882151

Strand: Direct

Name: pncA [C]

Synonym: DIP1840

Alternate gene names: 38234410

Gene position: 1881693-1882151 (Clockwise)

Preceding gene: 38234407

Following gene: 38234413

Centisome position: 75.61

GC content: 56.43

Gene sequence:

>459_bases
GTGGGCCACATGAATGCACTTCTTATTATCGATATCCACTCCAACTCCCCTACCCCCGAGGCCACCGAGATCACCCACGC
CATCGCCCTACATCTCGGCCAGCACCGCGGCGACTACTCCCACGTCATCGTAGCTCTTCAAGGCACTATCGCCGATGAGC
TAGCCGGTACTACCTTTGGCAATCAATTCATTAAAGACCCCGCCACCCAGGCCTTATCCGCTTTTGAGCGCACAGATGCC
ACCGGCACCAAACTCGGCGACTGGCTCCGTGCCAACAACATAGAACGCCTCGACGTTGTAGGCCTTGGCACCGAACTCGG
CATTCGCTCCAGCGTGTTAGACGCACTCGCCCAAGGATTTGATGTGCACGTGCACAAAAAACTCTGCGCTGCCGTATCAC
ACGACAACGCCCGCGCTGCCTATAACGAAATGGACATGTGCGGGGCGTTATTCGAATAA

Upstream 100 bases:

>100_bases
TGTCATCAATTGCTTTTGCAGGAGTAGTGATAAATTTATCTTCTTTTCCACCAAGAACTTGACACGCTCTCACACAGCTT
GAAGCCTATGCGTTGCTAGA

Downstream 100 bases:

>100_bases
GAGCTAGGTGCGTGAATCGAGCACTACGTCGAACTCCAGCAGCTCAGCGTCGGTTGCTATCGGCTTGCTGTGGGAGTTGC
CACCATGAACCTGACGGGCA

Product: hypothetical protein

Products: Nicotinate; pyrazinoic acid; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MGHMNALLIIDIHSNSPTPEATEITHAIALHLGQHRGDYSHVIVALQGTIADELAGTTFGNQFIKDPATQALSAFERTDA
TGTKLGDWLRANNIERLDVVGLGTELGIRSSVLDALAQGFDVHVHKKLCAAVSHDNARAAYNEMDMCGALFE

Sequences:

>Translated_152_residues
MGHMNALLIIDIHSNSPTPEATEITHAIALHLGQHRGDYSHVIVALQGTIADELAGTTFGNQFIKDPATQALSAFERTDA
TGTKLGDWLRANNIERLDVVGLGTELGIRSSVLDALAQGFDVHVHKKLCAAVSHDNARAAYNEMDMCGALFE
>Mature_151_residues
GHMNALLIIDIHSNSPTPEATEITHAIALHLGQHRGDYSHVIVALQGTIADELAGTTFGNQFIKDPATQALSAFERTDAT
GTKLGDWLRANNIERLDVVGLGTELGIRSSVLDALAQGFDVHVHKKLCAAVSHDNARAAYNEMDMCGALFE

Specific function: NAD biosynthesis; nicotinamide to NaMN; first step. [C]

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.1.- [C]

Molecular weight: Translated: 16332; Mature: 16200

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHMNALLIIDIHSNSPTPEATEITHAIALHLGQHRGDYSHVIVALQGTIADELAGTTFG
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCC
NQFIKDPATQALSAFERTDATGTKLGDWLRANNIERLDVVGLGTELGIRSSVLDALAQGF
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHCHHHHHHHHHHCCC
DVHVHKKLCAAVSHDNARAAYNEMDMCGALFE
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GHMNALLIIDIHSNSPTPEATEITHAIALHLGQHRGDYSHVIVALQGTIADELAGTTFG
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCC
NQFIKDPATQALSAFERTDATGTKLGDWLRANNIERLDVVGLGTELGIRSSVLDALAQGF
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHCHHHHHHHHHHCCC
DVHVHKKLCAAVSHDNARAAYNEMDMCGALFE
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nicotinamide; pyrazinamide; H2O [C]

Specific reaction: Nicotinamide + H2O = Nicotinate + NH3 pyrazinamide + H2O = pyrazinoic acid + NH3 [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA