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The map label for this gene is rhtC [H]

Identifier: 38234338

GI number: 38234338

Start: 1812354

End: 1812992

Strand: Reverse

Name: rhtC [H]

Synonym: DIP1767

Alternate gene names: 38234338

Gene position: 1812992-1812354 (Counterclockwise)

Preceding gene: 38234339

Following gene: 38234335

Centisome position: 72.85

GC content: 56.18

Gene sequence:

>639_bases
GTGGGGCTTAGCCAATTACTTACCCTCGTGGGCCTCAACGTGGTGGGAATGCTTACCCCTGGCCCTGATATTTTCCTTGT
TACCCGCATTGCCACCAAGTCGCGTCGCCATGCGTACGCCACTGTGGCCGGCATAGCCACTGGATTATTAGTGTGGGTCA
CGTTGACGGTTTTCGGCGCAACGGCCGTGCTCACCGCGTACCCCTCGGTACTTAGCGCTATCCAACTCGTGGGTGGTACG
TGGCTTTTATGGATGGGTACGAAATTGGTGCGGGTGGCGCGTCGCCAGCTGGGGGAGGGGGTTGCGGTTGCCTCGACTAT
CGACGCTCTCCTGGGAACCCCAGCACAGTGTTATCGCCAAGGACTAGCCACCAACCTTTCGAACCCTAAAGTGGTGTTGT
ATTTTGCGGCGATCATTGCACCGTTTCTTCCCACGAACCCGAGTTTGCTGACTGCGCTGTCGGTGATCGTGGTGATTGTG
TTGAGCAACCTTGTGATGTTCTCACTGTTAGCCACTGTCATTAGTACCAATGCGCTGCGGCGGGCCTTTTTGAAGGCTGG
GCCGTGGATTGATCTGGTTGCCGGTTGTTTCTTCATCATCGCTGGTATCGGGCTTATCATCGCAGCTACCCGCTCATAG

Upstream 100 bases:

>100_bases
TTGCTGCGCCATGGTGCAGACCCCACCGCCGGGCAACCAAGCGCTATCGACACAGCACGGATGTTTGGCCGTGAGGATCT
CGTCGAAAGGCTTCACGCAC

Downstream 100 bases:

>100_bases
ATATAAAAAATCCCGCCCTGTGACAACAGAGCGGGATTTTGCAATAGCTTAGGCCATCTTGTTCAGAGCGTGGGCCATGT
TGGACTTCTTGTTAGCCGCA

Product: putative LysE type translocator

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MGLSQLLTLVGLNVVGMLTPGPDIFLVTRIATKSRRHAYATVAGIATGLLVWVTLTVFGATAVLTAYPSVLSAIQLVGGT
WLLWMGTKLVRVARRQLGEGVAVASTIDALLGTPAQCYRQGLATNLSNPKVVLYFAAIIAPFLPTNPSLLTALSVIVVIV
LSNLVMFSLLATVISTNALRRAFLKAGPWIDLVAGCFFIIAGIGLIIAATRS

Sequences:

>Translated_212_residues
MGLSQLLTLVGLNVVGMLTPGPDIFLVTRIATKSRRHAYATVAGIATGLLVWVTLTVFGATAVLTAYPSVLSAIQLVGGT
WLLWMGTKLVRVARRQLGEGVAVASTIDALLGTPAQCYRQGLATNLSNPKVVLYFAAIIAPFLPTNPSLLTALSVIVVIV
LSNLVMFSLLATVISTNALRRAFLKAGPWIDLVAGCFFIIAGIGLIIAATRS
>Mature_211_residues
GLSQLLTLVGLNVVGMLTPGPDIFLVTRIATKSRRHAYATVAGIATGLLVWVTLTVFGATAVLTAYPSVLSAIQLVGGTW
LLWMGTKLVRVARRQLGEGVAVASTIDALLGTPAQCYRQGLATNLSNPKVVLYFAAIIAPFLPTNPSLLTALSVIVVIVL
SNLVMFSLLATVISTNALRRAFLKAGPWIDLVAGCFFIIAGIGLIIAATRS

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=30.3921568627451, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786522, Length=176, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22260; Mature: 22129

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSQLLTLVGLNVVGMLTPGPDIFLVTRIATKSRRHAYATVAGIATGLLVWVTLTVFGA
CCHHHHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVLTAYPSVLSAIQLVGGTWLLWMGTKLVRVARRQLGEGVAVASTIDALLGTPAQCYRQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
GLATNLSNPKVVLYFAAIIAPFLPTNPSLLTALSVIVVIVLSNLVMFSLLATVISTNALR
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFLKAGPWIDLVAGCFFIIAGIGLIIAATRS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLSQLLTLVGLNVVGMLTPGPDIFLVTRIATKSRRHAYATVAGIATGLLVWVTLTVFGA
CHHHHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVLTAYPSVLSAIQLVGGTWLLWMGTKLVRVARRQLGEGVAVASTIDALLGTPAQCYRQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
GLATNLSNPKVVLYFAAIIAPFLPTNPSLLTALSVIVVIVLSNLVMFSLLATVISTNALR
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFLKAGPWIDLVAGCFFIIAGIGLIIAATRS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]