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The map label for this gene is idi

Identifier: 38234301

GI number: 38234301

Start: 1771521

End: 1772072

Strand: Reverse

Name: idi

Synonym: DIP1730

Alternate gene names: 38234301

Gene position: 1772072-1771521 (Counterclockwise)

Preceding gene: 38234302

Following gene: 38234299

Centisome position: 71.21

GC content: 50.18

Gene sequence:

>552_bases
ATGAATGACGTTGAACTGGTTGTGCTTGCCGATGAATTCGGCAAGCCGTCCGGCACTGCTGTGAAAAGTGAAGTGCATAC
TACGGATACTCCTTTGCATTTCGCTTTTTCTTGTTATGTGCGAAACAACAAAGGTGATCTGCTCATTACTCGGCGAGCAC
TGAGCAAAAAGACATGGCCAGGAGTATGGACTAATTCTGCTTGCGGGCATCTTATGCCGGGGGAAACCCCTGAGCAAGCG
GTTGCCCGCAGGGTACCTCACGAGATTGGGATTTCGCAGGACAAATTAGTCAACATCGCGTGTGTCTTGCCCGATTTTAG
TTATCGCGCTGTGGATTCACGCGGCATTGTGGAGTGGGAAATCTGCCCAGTATTCACTGCAGCGGTGACAGACGACGCCC
TTTTGCCTGAAGCTGAAGAGGTGGACTCGTTAGTGTGGGTTGAACCAAGTAAGCTTATACATGCAGTGCATTCTGCCCCA
TTTGCTTTTAGCCCATGGATGGTTGAACAGCTGCAGCATGAGGCGCTTCGTACAGCACTTACGACTTCATAA

Upstream 100 bases:

>100_bases
GGAAGACAACAACATTGCGGCGCTGCTGGGAGAGTCTCCCGCCGTGGTTCCTGGCGTCATCGGAAGCTGGGTGCGCGGAT
AACCGTTAAGGTTATCTGTT

Downstream 100 bases:

>100_bases
AACCTGTGCGAACATGGGCTAACGGATCAGTGATGATGTGGTCTTGGGAGCCGTCGAGACGCATACTCATAACACTGCGA
CGTTGCCCATAAGGTTGCCA

Product: isopentenyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNDVELVVLADEFGKPSGTAVKSEVHTTDTPLHFAFSCYVRNNKGDLLITRRALSKKTWPGVWTNSACGHLMPGETPEQA
VARRVPHEIGISQDKLVNIACVLPDFSYRAVDSRGIVEWEICPVFTAAVTDDALLPEAEEVDSLVWVEPSKLIHAVHSAP
FAFSPWMVEQLQHEALRTALTTS

Sequences:

>Translated_183_residues
MNDVELVVLADEFGKPSGTAVKSEVHTTDTPLHFAFSCYVRNNKGDLLITRRALSKKTWPGVWTNSACGHLMPGETPEQA
VARRVPHEIGISQDKLVNIACVLPDFSYRAVDSRGIVEWEICPVFTAAVTDDALLPEAEEVDSLVWVEPSKLIHAVHSAP
FAFSPWMVEQLQHEALRTALTTS
>Mature_183_residues
MNDVELVVLADEFGKPSGTAVKSEVHTTDTPLHFAFSCYVRNNKGDLLITRRALSKKTWPGVWTNSACGHLMPGETPEQA
VARRVPHEIGISQDKLVNIACVLPDFSYRAVDSRGIVEWEICPVFTAAVTDDALLPEAEEVDSLVWVEPSKLIHAVHSAP
FAFSPWMVEQLQHEALRTALTTS

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789255, Length=177, Percent_Identity=48.5875706214689, Blast_Score=164, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6325140, Length=155, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_CORDI (P60923)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940068.1
- ProteinModelPortal:   P60923
- SMR:   P60923
- GeneID:   2650323
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1730
- NMPDR:   fig|257309.1.peg.1659
- HOGENOM:   HBG416977
- OMA:   ALSKKTW
- PhylomeDB:   P60923
- ProtClustDB:   PRK03759
- BioCyc:   CDIP257309:DIP1730-MONOMER
- BRENDA:   5.3.3.2
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 20193; Mature: 20193

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 68-68 ACT_SITE 120-120

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVELVVLADEFGKPSGTAVKSEVHTTDTPLHFAFSCYVRNNKGDLLITRRALSKKTWP
CCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEEEEECCCCCEEEEEHHHCCCCCC
GVWTNSACGHLMPGETPEQAVARRVPHEIGISQDKLVNIACVLPDFSYRAVDSRGIVEWE
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCHHEEEEEEECCCCCEEEECCCCEEEEE
ICPVFTAAVTDDALLPEAEEVDSLVWVEPSKLIHAVHSAPFAFSPWMVEQLQHEALRTAL
ECCEEEEHHCCCCCCCCHHHHCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TTS
CCC
>Mature Secondary Structure
MNDVELVVLADEFGKPSGTAVKSEVHTTDTPLHFAFSCYVRNNKGDLLITRRALSKKTWP
CCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEEEEECCCCCEEEEEHHHCCCCCC
GVWTNSACGHLMPGETPEQAVARRVPHEIGISQDKLVNIACVLPDFSYRAVDSRGIVEWE
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCHHEEEEEEECCCCCEEEECCCCEEEEE
ICPVFTAAVTDDALLPEAEEVDSLVWVEPSKLIHAVHSAPFAFSPWMVEQLQHEALRTAL
ECCEEEEHHCCCCCCCCHHHHCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TTS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910