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The map label for this gene is xerD [H]

Identifier: 38233776

GI number: 38233776

Start: 1184540

End: 1185475

Strand: Direct

Name: xerD [H]

Synonym: DIP1186

Alternate gene names: 38233776

Gene position: 1184540-1185475 (Clockwise)

Preceding gene: 38233775

Following gene: 38233777

Centisome position: 47.6

GC content: 45.41

Gene sequence:

>936_bases
ATGGGCTCAATAAGTAATATTGCTCGTCAATGGCTAACTCACTTAGCAGTGGAAAAAGGAGTTAGCGATAACACATTGTC
TAATTATCGTCGTGATCTTGAACGGTATACACGGTGGCTGCAAGTACAGGGAATCACAGATATTGAGAATATCTCCGCAC
AAGATATTGAAAGATATGTTCAAGAGTTGCGTAAGGGGGATAGTGATACTGGAAAAAAACCTCTAGCTGCCTCATCTGCT
GCGCGAGCTTTGATTGTTGCTCGTGGTCTACATCGTTTTGCATTGTTAGAAAACTTAGTGGAGAACGATGTATCTGCTGA
TGTCTCTCCACCTGCAATGGGGCGTCACCTGCCTGATACCCTCTCAGTCGAGGAAGTGAATCGTCTAATAGAAGCTATAC
CCATAGATGATGCGGCTTCGCCAGAAAATCTTAGGGATTGCGCTCTACTGGAGTTCCTCTATGCTACTGGAGCCCGCATT
TCGGAAGCAGTAGGTCTAGTGGTGGACGACGTGGCTGCAATTGTCGAAAATGAAGGCATTGTCCGAATAACTGGAAAGGG
CAACAAACAGCGTATTGTGCCTGTTGGTGATCAGTGTTTGTCAGCGCTCGAGCGATATGTCGTGAGAAGCAGACCGGCAA
TGTCAAAAGGGAAATCGCACGCACTTTTCCTTAATAAACGTGGCGGACAATTATCTAGACAAAGCGCTTGGCAAATTCTC
AAAAACTCAGCTCAACGCGCAGGAATTGAAAAAGATATTTCTCCACATACTTTGCGCCATAGTTTTGCCACTCATCTTTT
AGAAGGTGGGGCTGATGTTCGAGTAGTACAAGAATTGTTAGGGCATTCGTCGGTCACAACTACACAGATATACACCCATG
TAACTGCCGATAATCTACGATTTGTCTGGTCTCGTTCACATCCGCGTGCTCACTAA

Upstream 100 bases:

>100_bases
AGCATGGAGCATCTTTACCGAGTCGAGCCACCGAATTTGAAATTAGACCTACTTCATTGGCACAACGACATCAAGATTTA
ACAGTACCTCGCCGATAATT

Downstream 100 bases:

>100_bases
CATGGTTGGATTTTGTAAAGTCAGCAAACTAGATTTGTGAATTTTTTCTTCGTAAAATTGCTTCAAAGACACGGAATGAA
TCCGAAGCGTGTAATTTATA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MGSISNIARQWLTHLAVEKGVSDNTLSNYRRDLERYTRWLQVQGITDIENISAQDIERYVQELRKGDSDTGKKPLAASSA
ARALIVARGLHRFALLENLVENDVSADVSPPAMGRHLPDTLSVEEVNRLIEAIPIDDAASPENLRDCALLEFLYATGARI
SEAVGLVVDDVAAIVENEGIVRITGKGNKQRIVPVGDQCLSALERYVVRSRPAMSKGKSHALFLNKRGGQLSRQSAWQIL
KNSAQRAGIEKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHVTADNLRFVWSRSHPRAH

Sequences:

>Translated_311_residues
MGSISNIARQWLTHLAVEKGVSDNTLSNYRRDLERYTRWLQVQGITDIENISAQDIERYVQELRKGDSDTGKKPLAASSA
ARALIVARGLHRFALLENLVENDVSADVSPPAMGRHLPDTLSVEEVNRLIEAIPIDDAASPENLRDCALLEFLYATGARI
SEAVGLVVDDVAAIVENEGIVRITGKGNKQRIVPVGDQCLSALERYVVRSRPAMSKGKSHALFLNKRGGQLSRQSAWQIL
KNSAQRAGIEKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHVTADNLRFVWSRSHPRAH
>Mature_310_residues
GSISNIARQWLTHLAVEKGVSDNTLSNYRRDLERYTRWLQVQGITDIENISAQDIERYVQELRKGDSDTGKKPLAASSAA
RALIVARGLHRFALLENLVENDVSADVSPPAMGRHLPDTLSVEEVNRLIEAIPIDDAASPENLRDCALLEFLYATGARIS
EAVGLVVDDVAAIVENEGIVRITGKGNKQRIVPVGDQCLSALERYVVRSRPAMSKGKSHALFLNKRGGQLSRQSAWQILK
NSAQRAGIEKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHVTADNLRFVWSRSHPRAH

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=303, Percent_Identity=43.8943894389439, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1790244, Length=312, Percent_Identity=34.2948717948718, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790768, Length=187, Percent_Identity=31.0160427807487, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34332; Mature: 34201

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSISNIARQWLTHLAVEKGVSDNTLSNYRRDLERYTRWLQVQGITDIENISAQDIERYV
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
QELRKGDSDTGKKPLAASSAARALIVARGLHRFALLENLVENDVSADVSPPAMGRHLPDT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LSVEEVNRLIEAIPIDDAASPENLRDCALLEFLYATGARISEAVGLVVDDVAAIVENEGI
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
VRITGKGNKQRIVPVGDQCLSALERYVVRSRPAMSKGKSHALFLNKRGGQLSRQSAWQIL
EEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
KNSAQRAGIEKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHVTADNLR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHEEEEECCCEE
FVWSRSHPRAH
EEEECCCCCCC
>Mature Secondary Structure 
GSISNIARQWLTHLAVEKGVSDNTLSNYRRDLERYTRWLQVQGITDIENISAQDIERYV
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
QELRKGDSDTGKKPLAASSAARALIVARGLHRFALLENLVENDVSADVSPPAMGRHLPDT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LSVEEVNRLIEAIPIDDAASPENLRDCALLEFLYATGARISEAVGLVVDDVAAIVENEGI
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
VRITGKGNKQRIVPVGDQCLSALERYVVRSRPAMSKGKSHALFLNKRGGQLSRQSAWQIL
EEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
KNSAQRAGIEKDISPHTLRHSFATHLLEGGADVRVVQELLGHSSVTTTQIYTHVTADNLR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHEEEEECCCEE
FVWSRSHPRAH
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]