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The map label for this gene is nudF [H]

Identifier: 38233775

GI number: 38233775

Start: 1183899

End: 1184537

Strand: Direct

Name: nudF [H]

Synonym: DIP1185

Alternate gene names: 38233775

Gene position: 1183899-1184537 (Clockwise)

Preceding gene: 38233774

Following gene: 38233776

Centisome position: 47.57

GC content: 46.64

Gene sequence:

>639_bases
ATGACTCCTCATTCGTTTGTCGTGACAGATAGTACGTTGCTTTTGGATGCTCCAATTATTGCGGTGCGACGAGACAAGGT
GCTTATGCCGAAAGGAAACGAGAGCTATCGAGAAATCGTCGAGCATTATGGCGCTGTAGCCATAGTAGCTCGCGATGAAT
CTGGGCGGATTCTACTGATAAAACAATATAGGCATAGTGTAGGTAGGCGCATGTGGGAGCTTCCAGCTGGGTTACTTGAT
ATCCCAGCTGAATCTGAGTTGCAGGCTGCTCAACGAGAATTAAAAGAAGAAGCAGGACTCGCATCTCATCATTGGTCTTG
CATAATTGATTTAGTTACTAGTCCCGGTTTTTGTGACGAAGCAGTTCGAATCTTCCTAGCTGATCGAGTATATGCTGTGC
CTCGGCCGGAGGCGTCAGATGAAGAAGCTGACCTTACGACACAATGGGTCGCGCTCGAAGATGCTATTGAAATGATCATG
CGTGGAAAGATCGTGAATTCTATTGCGATCGCAGGTATTTTCGCTGCACGTGAGCATATCGAGCATGGAGCATCTTTACC
GAGTCGAGCCACCGAATTTGAAATTAGACCTACTTCATTGGCACAACGACATCAAGATTTAACAGTACCTCGCCGATAA

Upstream 100 bases:

>100_bases
AATCGACGGTAAATCTGGTGCTTATGGCGCAGCGGGGAATGTCGACGCTACATCTCCAGGAATTAAAAATCCTGAGTAGA
TTGCAGCTATCGTTGAGATT

Downstream 100 bases:

>100_bases
TTATGGGCTCAATAAGTAATATTGCTCGTCAATGGCTAACTCACTTAGCAGTGGAAAAAGGAGTTAGCGATAACACATTG
TCTAATTATCGTCGTGATCT

Product: hypothetical protein

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTPHSFVVTDSTLLLDAPIIAVRRDKVLMPKGNESYREIVEHYGAVAIVARDESGRILLIKQYRHSVGRRMWELPAGLLD
IPAESELQAAQRELKEEAGLASHHWSCIIDLVTSPGFCDEAVRIFLADRVYAVPRPEASDEEADLTTQWVALEDAIEMIM
RGKIVNSIAIAGIFAAREHIEHGASLPSRATEFEIRPTSLAQRHQDLTVPRR

Sequences:

>Translated_212_residues
MTPHSFVVTDSTLLLDAPIIAVRRDKVLMPKGNESYREIVEHYGAVAIVARDESGRILLIKQYRHSVGRRMWELPAGLLD
IPAESELQAAQRELKEEAGLASHHWSCIIDLVTSPGFCDEAVRIFLADRVYAVPRPEASDEEADLTTQWVALEDAIEMIM
RGKIVNSIAIAGIFAAREHIEHGASLPSRATEFEIRPTSLAQRHQDLTVPRR
>Mature_211_residues
TPHSFVVTDSTLLLDAPIIAVRRDKVLMPKGNESYREIVEHYGAVAIVARDESGRILLIKQYRHSVGRRMWELPAGLLDI
PAESELQAAQRELKEEAGLASHHWSCIIDLVTSPGFCDEAVRIFLADRVYAVPRPEASDEEADLTTQWVALEDAIEMIMR
GKIVNSIAIAGIFAAREHIEHGASLPSRATEFEIRPTSLAQRHQDLTVPRR

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 23712; Mature: 23581

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHSFVVTDSTLLLDAPIIAVRRDKVLMPKGNESYREIVEHYGAVAIVARDESGRILLI
CCCCCEEEECCEEEEECCEEEEECCEEECCCCCHHHHHHHHHCCEEEEEEECCCCCEEEE
KQYRHSVGRRMWELPAGLLDIPAESELQAAQRELKEEAGLASHHWSCIIDLVTSPGFCDE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHEEECCCCCCHHH
AVRIFLADRVYAVPRPEASDEEADLTTQWVALEDAIEMIMRGKIVNSIAIAGIFAAREHI
HHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHGASLPSRATEFEIRPTSLAQRHQDLTVPRR
HHCCCCCCCCCEEEECCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPHSFVVTDSTLLLDAPIIAVRRDKVLMPKGNESYREIVEHYGAVAIVARDESGRILLI
CCCCEEEECCEEEEECCEEEEECCEEECCCCCHHHHHHHHHCCEEEEEEECCCCCEEEE
KQYRHSVGRRMWELPAGLLDIPAESELQAAQRELKEEAGLASHHWSCIIDLVTSPGFCDE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHEEECCCCCCHHH
AVRIFLADRVYAVPRPEASDEEADLTTQWVALEDAIEMIMRGKIVNSIAIAGIFAAREHI
HHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHGASLPSRATEFEIRPTSLAQRHQDLTVPRR
HHCCCCCCCCCEEEECCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]