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The map label for this gene is etfA [H]

Identifier: 38233665

GI number: 38233665

Start: 1052119

End: 1053072

Strand: Direct

Name: etfA [H]

Synonym: DIP1071

Alternate gene names: 38233665

Gene position: 1052119-1053072 (Clockwise)

Preceding gene: 38233664

Following gene: 38233666

Centisome position: 42.28

GC content: 53.98

Gene sequence:

>954_bases
ATGTCTACTGTTTATGTCCTCGTAGAACACGCAAATGGTCAGGTTCTTCCCGCAACCGGAGAGCTTATTACTGCCGCCCG
TCCGCTAGGTGATGTAACGGCAGTGGTTGTTGGCACACCAGGCAGCCATGAAGCACTAGTCAGCCAAATTGCTGAATACA
GTGCAACAGCCATTGTGGCCGCACAGGTCGCAGATGCGGACAGTCGAGTTGTTATTCCACAGGCTGATGCGTTGTCTATG
CTGGCAGCAGCCCAACCGGGTCCAATTCTGCTGGACTCCGGAGCTCATGGCAATGAAATCGCGGGCCGTCTGGCAGCCCG
TTTAGCTTCCGGAGTGCTGTGCAACGTTGTAGGCGTGAACGCAGATCGCACAGCTGTGATGTCGATTTTCGGTGATACCG
TCGATGTTTCCGCAGCTGTGGGTGGTGCGAGCCCGATCTATACTTTGCGTCCAGGTGCTGTGGAAGCTGTTCCAGCGCCA
TCGCAGCCAGCAGTGTCTGTGATGGATATTCCTGCAACCGGCGTCAAAGACGTCAAGGTTAGTTCCTTTACCCCCGCGGC
TCAGGGGGATCGACCTGATCTAAGTACCGCTAAGGTCGTGATCGCTGGTGGTCGAGGCGTGGAATCCGCAGAAAACTTCA
CCACTATTGTCGAGCCACTGGCTGATGCCCTCAACGGTGCAGTTGGAGCCACCCGCGATGCAGTAGATCTGGGTTACTAT
CCAGCGCAATATCAGGTGGGACAAACGGGAGTGACTGTTTCTCCGGATCTGTACATCGGTTTGGGTATTTCCGGAGCTAT
CCAGCACACATCAGGCATGCAGACGTCGAAGAAAATCGTCGTTATCAACAATGATGCAGATGCGCCATTCTTCCAGATTG
CAGATCTTGGAGTCGTCGGTGATATCCATGAGATCGCACCGTTGCTCGTCAAAGAAATTGCTCAACGCTCTTAA

Upstream 100 bases:

>100_bases
TCGCCGGTGAAGTTATTAACACATCCTCTGCTGAAGCAGCGGCAAAGATTGCAGACTTCTTGGCTGCGGAAAAGCTTATT
TAAGGTTTAGGAGAACAGAT

Downstream 100 bases:

>100_bases
AAGTAGTGGTATATCCAAACGCGGGTTATTTTGACTAGAAAATAGCTCGCGTTCGGTGTTTTAGCACTTCATAGCGGCTT
TCTATGCGCATTGATAGAGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSTVYVLVEHANGQVLPATGELITAARPLGDVTAVVVGTPGSHEALVSQIAEYSATAIVAAQVADADSRVVIPQADALSM
LAAAQPGPILLDSGAHGNEIAGRLAARLASGVLCNVVGVNADRTAVMSIFGDTVDVSAAVGGASPIYTLRPGAVEAVPAP
SQPAVSVMDIPATGVKDVKVSSFTPAAQGDRPDLSTAKVVIAGGRGVESAENFTTIVEPLADALNGAVGATRDAVDLGYY
PAQYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTSKKIVVINNDADAPFFQIADLGVVGDIHEIAPLLVKEIAQRS

Sequences:

>Translated_317_residues
MSTVYVLVEHANGQVLPATGELITAARPLGDVTAVVVGTPGSHEALVSQIAEYSATAIVAAQVADADSRVVIPQADALSM
LAAAQPGPILLDSGAHGNEIAGRLAARLASGVLCNVVGVNADRTAVMSIFGDTVDVSAAVGGASPIYTLRPGAVEAVPAP
SQPAVSVMDIPATGVKDVKVSSFTPAAQGDRPDLSTAKVVIAGGRGVESAENFTTIVEPLADALNGAVGATRDAVDLGYY
PAQYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTSKKIVVINNDADAPFFQIADLGVVGDIHEIAPLLVKEIAQRS
>Mature_316_residues
STVYVLVEHANGQVLPATGELITAARPLGDVTAVVVGTPGSHEALVSQIAEYSATAIVAAQVADADSRVVIPQADALSML
AAAQPGPILLDSGAHGNEIAGRLAARLASGVLCNVVGVNADRTAVMSIFGDTVDVSAAVGGASPIYTLRPGAVEAVPAPS
QPAVSVMDIPATGVKDVKVSSFTPAAQGDRPDLSTAKVVIAGGRGVESAENFTTIVEPLADALNGAVGATRDAVDLGYYP
AQYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTSKKIVVINNDADAPFFQIADLGVVGDIHEIAPLLVKEIAQRS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=335, Percent_Identity=32.5373134328358, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=34.0823970037453, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI1787990, Length=260, Percent_Identity=29.2307692307692, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786226, Length=133, Percent_Identity=37.593984962406, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082157, Length=228, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=316, Percent_Identity=36.7088607594937, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=300, Percent_Identity=31.3333333333333, Blast_Score=147, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17136898, Length=341, Percent_Identity=33.7243401759531, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24652801, Length=341, Percent_Identity=33.7243401759531, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32022; Mature: 31890

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVYVLVEHANGQVLPATGELITAARPLGDVTAVVVGTPGSHEALVSQIAEYSATAIVA
CCEEEEEEECCCCEEEECCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHEEEE
AQVADADSRVVIPQADALSMLAAAQPGPILLDSGAHGNEIAGRLAARLASGVLCNVVGVN
EEECCCCCEEEEECHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECC
ADRTAVMSIFGDTVDVSAAVGGASPIYTLRPGAVEAVPAPSQPAVSVMDIPATGVKDVKV
CCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEECCCCCCCCEEEEECCCCCCCCEEE
SSFTPAAQGDRPDLSTAKVVIAGGRGVESAENFTTIVEPLADALNGAVGATRDAVDLGYY
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCC
PAQYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTSKKIVVINNDADAPFFQIADLGVVG
CCEEEECCCCEEECCCEEEEECCCCCEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCC
DIHEIAPLLVKEIAQRS
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVYVLVEHANGQVLPATGELITAARPLGDVTAVVVGTPGSHEALVSQIAEYSATAIVA
CEEEEEEECCCCEEEECCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHEEEE
AQVADADSRVVIPQADALSMLAAAQPGPILLDSGAHGNEIAGRLAARLASGVLCNVVGVN
EEECCCCCEEEEECHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECC
ADRTAVMSIFGDTVDVSAAVGGASPIYTLRPGAVEAVPAPSQPAVSVMDIPATGVKDVKV
CCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEECCCCCCCCEEEEECCCCCCCCEEE
SSFTPAAQGDRPDLSTAKVVIAGGRGVESAENFTTIVEPLADALNGAVGATRDAVDLGYY
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCC
PAQYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTSKKIVVINNDADAPFFQIADLGVVG
CCEEEECCCCEEECCCEEEEECCCCCEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCC
DIHEIAPLLVKEIAQRS
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]