| Definition | Corynebacterium diphtheriae NCTC 13129 chromosome, complete genome. |
|---|---|
| Accession | NC_002935 |
| Length | 2,488,635 |
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The map label for this gene is hypF [H]
Identifier: 38233276
GI number: 38233276
Start: 644718
End: 646952
Strand: Reverse
Name: hypF [H]
Synonym: DIP0669
Alternate gene names: 38233276
Gene position: 646952-644718 (Counterclockwise)
Preceding gene: 38233283
Following gene: 38233274
Centisome position: 26.0
GC content: 56.73
Gene sequence:
>2235_bases ATGTTGCGCACTCGATACCTTCTCAGGGGTGTAGTTCAGGGGGTAGGCTTTCGCCCCCACGTTGCCGCCGTCGCCGCCCG TCATCGCATAACTGGCTTGTGTGGCAACAACGATCTTGAGGTGTTTGTCGAGGCCCAAGCCCTATCCGAGGACATCCTCG ATGCATTCATTTCCGACGTGCTCGCCACCCTCCCACCACTCGCACACGTGGTAACCGTCACGCAGTCATCATGCCCACCG ATCAGCCACGAAACAGACTTCCGCATCGTCGCATCCGAGCATCTCCCCGGCGCGCGCACACTGATCCCACCCGATGTTGC GACCTGCCCTGATTGTTTGGCGGATATGGCGGATCCAAACAATCGCCGTTATCGCTACCCTTTTACAACGTGTACTCATT GTGGACCGCGTTTGAGCATCATTGAGGACCTTCCCTATGACCGACCGCTAACAACAATGAAGCATTTCCCCATGTGCCCG CAGTGCGCCAAGGAGTATTCCGATCCGCACGATCGCCGCTATCATGCCCAGCCAATTAGCTGCCCTGATTGCGGTCCGTC GTTGTGGGTAGAGGCTACTGAAACGCCTGGCAGGCCACCGCTACGCTTGCGTGTCGACGACCCCATCGCTTACTGCCGTG ACGCGATCTCGAAGGGAAAGATTGTAGCCGTTAAGGGCCTAGGCGGATTCCATCTCATGTGCGACGCAACCAATGACGAA GCAGTGCGAACGCTGCGCGAACGTAAGCATCGCCCCACAAAACCGCTGGCCGTTATGATTCCCGATGTGGAAAAAGCCCG TGAGCTAGCCAGATTAGATGCCGATACCACGGCGGTGCTTACTGATCCCGCGCATCCCATCGTTTTAGTGCCCACGACAA GCAAGCAACGCCTCAAACTCAGCCTACTCATTGCTCCAGGCTTGGACTATGTAGGACTCGTGCTGCCCTATACACCACTG CATACGCTCTTGGTTGACTCCCCTGTCGTAGCGACTTCTGCCAATAACTCCGGCGAGCCCCTGTGCTGGGATAATGACGT AGCGCGCGAGAATCTGACGCATCTTGCCGATGTGTTCCTCATGCACGATCGCCCGATTCATATTCCTGTGGAAGATTCGG TGGTCGTTCCCAGCGCACACGGCATTGTTCCCATTAGACGATCGCGGGGGTTTGCCCCACTGCCACTGACGATTCCCACT TTTGCCGAAGCTGGCCAACCGGCACTGAGCACGCTCGCAGTCGGTGGAGAACTAAAAAACACTTTTACCCTTGCTCACGA AGACTACGCACATATCTCTAGCCACATTGGGGATATGGGATCGTGGCCAAGCCAGCAGGCGTTTCATCGCGCAGTTGATC AAATGCTGAGCATGCAGCGCACCCGCCCCGACTTGTTGGTCTGCGATCTTCATCCCAGCTATGCCACCACCGCTTGGGCA CAGCGCTATAGCGAATCCAACGATATTCCGCTTGTTCAGGTTCAGCATCATGAAGCCCATGCGATGGCGCTTCTTGCTGA ACACCGCGCATGTGGTACACCAGCGGTCATTCTGGCCGCAGACGGCACCGGCTATGGGCACGACAATACGATCTGGGGTG GCGAGCTTCTTTCCTATCATCCTGATACTGGATTCGAGCGCACGTGGCACGTCCCCACCTTTGAACTTGTTGGTGGCGAT CGCGCGGTCCAGCATCCGTGGCGGATCGCAGCAGGCATCGCGCATGCGTGGGGTCTGGACTGGGATTGTGGGAAAGAATC GTCGATTCTTTCCCACACATCTGCGGCAGAGATCGAACTAGTAGAAAGTCAGTTGTCGTCTGGCTTTGGCGTGGTGCGTA CAAGTTCGCTGGGCCGTGTGTTTGATGCTGCGGCTGCAATCGTGGGGATTCACCCGCCGAGTTTTGAGGCGGAGTCAGCG ATGTTGTTCGAGGCTGCGGCTAGAAATTGCGAGAAACGAGAATCAGAGGCGACGTCGTTTCCGGAGGCATTTGCGGAACT TCTTGAGACTCGAAACCCGTGGACGTTTCATCATGCGGTAGCGCAGATTCTTCAGCACCACATCGATGAGGCTGCAGTCG GCATGAGTACCGGTCTTACTGGTGGTTGCGCATTGAATCAACTGTTGTCGAGCATGTTGCGCGTTGATATGCGCCATCAA ATTGTGCCGCCGAATGATGGCGGGTTAAGCCTCGGCCAGGCGGTGCTGGGACGTTGGACTGTGAGCACCGCCTAG
Upstream 100 bases:
>100_bases CCCGTACGACAAGAACGCGGCGGCCTTGCGCTGCCCGATCGACGGCACGCGCCAACTGAGAACTTAACGCCACTTCATGC ACAAGCACTAGCCTAGAACT
Downstream 100 bases:
>100_bases CTTAGTCATTAGCAGATTCGTGGTAGCGGGTCGCCGACCAACATGTCCACCATGCGGGAGCCGCCGAAGCCGGTACGCAG GACGACGGATGCGGCTGGTT
Product: putative hydrogenase maturation protein
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 744; Mature: 744
Protein sequence:
>744_residues MLRTRYLLRGVVQGVGFRPHVAAVAARHRITGLCGNNDLEVFVEAQALSEDILDAFISDVLATLPPLAHVVTVTQSSCPP ISHETDFRIVASEHLPGARTLIPPDVATCPDCLADMADPNNRRYRYPFTTCTHCGPRLSIIEDLPYDRPLTTMKHFPMCP QCAKEYSDPHDRRYHAQPISCPDCGPSLWVEATETPGRPPLRLRVDDPIAYCRDAISKGKIVAVKGLGGFHLMCDATNDE AVRTLRERKHRPTKPLAVMIPDVEKARELARLDADTTAVLTDPAHPIVLVPTTSKQRLKLSLLIAPGLDYVGLVLPYTPL HTLLVDSPVVATSANNSGEPLCWDNDVARENLTHLADVFLMHDRPIHIPVEDSVVVPSAHGIVPIRRSRGFAPLPLTIPT FAEAGQPALSTLAVGGELKNTFTLAHEDYAHISSHIGDMGSWPSQQAFHRAVDQMLSMQRTRPDLLVCDLHPSYATTAWA QRYSESNDIPLVQVQHHEAHAMALLAEHRACGTPAVILAADGTGYGHDNTIWGGELLSYHPDTGFERTWHVPTFELVGGD RAVQHPWRIAAGIAHAWGLDWDCGKESSILSHTSAAEIELVESQLSSGFGVVRTSSLGRVFDAAAAIVGIHPPSFEAESA MLFEAAARNCEKRESEATSFPEAFAELLETRNPWTFHHAVAQILQHHIDEAAVGMSTGLTGGCALNQLLSSMLRVDMRHQ IVPPNDGGLSLGQAVLGRWTVSTA
Sequences:
>Translated_744_residues MLRTRYLLRGVVQGVGFRPHVAAVAARHRITGLCGNNDLEVFVEAQALSEDILDAFISDVLATLPPLAHVVTVTQSSCPP ISHETDFRIVASEHLPGARTLIPPDVATCPDCLADMADPNNRRYRYPFTTCTHCGPRLSIIEDLPYDRPLTTMKHFPMCP QCAKEYSDPHDRRYHAQPISCPDCGPSLWVEATETPGRPPLRLRVDDPIAYCRDAISKGKIVAVKGLGGFHLMCDATNDE AVRTLRERKHRPTKPLAVMIPDVEKARELARLDADTTAVLTDPAHPIVLVPTTSKQRLKLSLLIAPGLDYVGLVLPYTPL HTLLVDSPVVATSANNSGEPLCWDNDVARENLTHLADVFLMHDRPIHIPVEDSVVVPSAHGIVPIRRSRGFAPLPLTIPT FAEAGQPALSTLAVGGELKNTFTLAHEDYAHISSHIGDMGSWPSQQAFHRAVDQMLSMQRTRPDLLVCDLHPSYATTAWA QRYSESNDIPLVQVQHHEAHAMALLAEHRACGTPAVILAADGTGYGHDNTIWGGELLSYHPDTGFERTWHVPTFELVGGD RAVQHPWRIAAGIAHAWGLDWDCGKESSILSHTSAAEIELVESQLSSGFGVVRTSSLGRVFDAAAAIVGIHPPSFEAESA MLFEAAARNCEKRESEATSFPEAFAELLETRNPWTFHHAVAQILQHHIDEAAVGMSTGLTGGCALNQLLSSMLRVDMRHQ IVPPNDGGLSLGQAVLGRWTVSTA >Mature_744_residues MLRTRYLLRGVVQGVGFRPHVAAVAARHRITGLCGNNDLEVFVEAQALSEDILDAFISDVLATLPPLAHVVTVTQSSCPP ISHETDFRIVASEHLPGARTLIPPDVATCPDCLADMADPNNRRYRYPFTTCTHCGPRLSIIEDLPYDRPLTTMKHFPMCP QCAKEYSDPHDRRYHAQPISCPDCGPSLWVEATETPGRPPLRLRVDDPIAYCRDAISKGKIVAVKGLGGFHLMCDATNDE AVRTLRERKHRPTKPLAVMIPDVEKARELARLDADTTAVLTDPAHPIVLVPTTSKQRLKLSLLIAPGLDYVGLVLPYTPL HTLLVDSPVVATSANNSGEPLCWDNDVARENLTHLADVFLMHDRPIHIPVEDSVVVPSAHGIVPIRRSRGFAPLPLTIPT FAEAGQPALSTLAVGGELKNTFTLAHEDYAHISSHIGDMGSWPSQQAFHRAVDQMLSMQRTRPDLLVCDLHPSYATTAWA QRYSESNDIPLVQVQHHEAHAMALLAEHRACGTPAVILAADGTGYGHDNTIWGGELLSYHPDTGFERTWHVPTFELVGGD RAVQHPWRIAAGIAHAWGLDWDCGKESSILSHTSAAEIELVESQLSSGFGVVRTSSLGRVFDAAAAIVGIHPPSFEAESA MLFEAAARNCEKRESEATSFPEAFAELLETRNPWTFHHAVAQILQHHIDEAAVGMSTGLTGGCALNQLLSSMLRVDMRHQ IVPPNDGGLSLGQAVLGRWTVSTA
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=765, Percent_Identity=38.3006535947712, Blast_Score=388, Evalue=1e-109,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 81169; Mature: 81169
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLRTRYLLRGVVQGVGFRPHVAAVAARHRITGLCGNNDLEVFVEAQALSEDILDAFISDV CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHH LATLPPLAHVVTVTQSSCPPISHETDFRIVASEHLPGARTLIPPDVATCPDCLADMADPN HHHCCCHHHEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCC NRRYRYPFTTCTHCGPRLSIIEDLPYDRPLTTMKHFPMCPQCAKEYSDPHDRRYHAQPIS CCEEECCCCHHHCCCCCCHHHHHCCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC CPDCGPSLWVEATETPGRPPLRLRVDDPIAYCRDAISKGKIVAVKGLGGFHLMCDATNDE CCCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCHH AVRTLRERKHRPTKPLAVMIPDVEKARELARLDADTTAVLTDPAHPIVLVPTTSKQRLKL HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEEE SLLIAPGLDYVGLVLPYTPLHTLLVDSPVVATSANNSGEPLCWDNDVARENLTHLADVFL EEEEECCCCHHHHHCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH MHDRPIHIPVEDSVVVPSAHGIVPIRRSRGFAPLPLTIPTFAEAGQPALSTLAVGGELKN CCCCCEEECCCCCEECCCCCCCEEECCCCCCCCCCEECCCHHHCCCCHHHHHHCCCCCCC TFTLAHEDYAHISSHIGDMGSWPSQQAFHRAVDQMLSMQRTRPDLLVCDLHPSYATTAWA EEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH QRYSESNDIPLVQVQHHEAHAMALLAEHRACGTPAVILAADGTGYGHDNTIWGGELLSYH HHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCEEEC PDTGFERTWHVPTFELVGGDRAVQHPWRIAAGIAHAWGLDWDCGKESSILSHTSAAEIEL CCCCCCCEECCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHH VESQLSSGFGVVRTSSLGRVFDAAAAIVGIHPPSFEAESAMLFEAAARNCEKRESEATSF HHHHHHCCCCEEEECCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH PEAFAELLETRNPWTFHHAVAQILQHHIDEAAVGMSTGLTGGCALNQLLSSMLRVDMRHQ HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC IVPPNDGGLSLGQAVLGRWTVSTA CCCCCCCCCHHHHHHHCCEEECCC >Mature Secondary Structure MLRTRYLLRGVVQGVGFRPHVAAVAARHRITGLCGNNDLEVFVEAQALSEDILDAFISDV CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHH LATLPPLAHVVTVTQSSCPPISHETDFRIVASEHLPGARTLIPPDVATCPDCLADMADPN HHHCCCHHHEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCC NRRYRYPFTTCTHCGPRLSIIEDLPYDRPLTTMKHFPMCPQCAKEYSDPHDRRYHAQPIS CCEEECCCCHHHCCCCCCHHHHHCCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC CPDCGPSLWVEATETPGRPPLRLRVDDPIAYCRDAISKGKIVAVKGLGGFHLMCDATNDE CCCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCHH AVRTLRERKHRPTKPLAVMIPDVEKARELARLDADTTAVLTDPAHPIVLVPTTSKQRLKL HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEEE SLLIAPGLDYVGLVLPYTPLHTLLVDSPVVATSANNSGEPLCWDNDVARENLTHLADVFL EEEEECCCCHHHHHCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH MHDRPIHIPVEDSVVVPSAHGIVPIRRSRGFAPLPLTIPTFAEAGQPALSTLAVGGELKN CCCCCEEECCCCCEECCCCCCCEEECCCCCCCCCCEECCCHHHCCCCHHHHHHCCCCCCC TFTLAHEDYAHISSHIGDMGSWPSQQAFHRAVDQMLSMQRTRPDLLVCDLHPSYATTAWA EEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH QRYSESNDIPLVQVQHHEAHAMALLAEHRACGTPAVILAADGTGYGHDNTIWGGELLSYH HHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCEEEC PDTGFERTWHVPTFELVGGDRAVQHPWRIAAGIAHAWGLDWDCGKESSILSHTSAAEIEL CCCCCCCEECCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHH VESQLSSGFGVVRTSSLGRVFDAAAAIVGIHPPSFEAESAMLFEAAARNCEKRESEATSF HHHHHHCCCCEEEECCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH PEAFAELLETRNPWTFHHAVAQILQHHIDEAAVGMSTGLTGGCALNQLLSSMLRVDMRHQ HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC IVPPNDGGLSLGQAVLGRWTVSTA CCCCCCCCCHHHHHHHCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]