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The map label for this gene is malL [H]

Identifier: 38233142

GI number: 38233142

Start: 500305

End: 502095

Strand: Reverse

Name: malL [H]

Synonym: DIP0533

Alternate gene names: 38233142

Gene position: 502095-500305 (Counterclockwise)

Preceding gene: 38233147

Following gene: 38233141

Centisome position: 20.18

GC content: 51.87

Gene sequence:

>1791_bases
GTGCACCCGAACTGCAACGATATAGCGCAGCCGCATCCCCTACTTCCGATGGATATTAACAGAGCCTTAGCTAGAAATGA
ACCAATTTGCAGATATTTTTATCCCCACACCACTACCCCCACTACCCCACTGGTAATAACCTCATACCTCACAACGAAAA
ACACCTCGCGTGAGCTCAGTACGATAGAGAGCATGACGTCGAAAAGCCTTCCAACTCGCACCACGTTAAGCTCGGGAACG
TTCTATCAGATTTACCCTCCTAGCTTTGCCGATTCTAATAAAGACGGCATCGGAGATTTCCGTGGAATCATCTCGCGACT
CGACTATCTCAGCGACCTTGGCATCACCGGAATCTGGCTCAACGCGTGCTTTGATTCACCTTTTAAAGACGGCGGCTACG
ATGTGCGCGACTACACAAAGGTGGCTTCTCGGTACGGCACCCATGAGGATTTGGTGGAGCTTTTCCACCAAGCGCATGCC
CGCGGAATTGCCATTATCTTGGATCTGGTTCCTGGTCACACCAGCGAACAACACCCTTGGTTTCAACAAAGTGCTGCTAG
TAAATACACAGATTTTGATGACCGCTATATTTGGACTTCGCACGCATTTGAGGGTGGTGCGGGGCTAGCTTTTATTGGCG
GCGAACACCCCCGCAACGGTGCGTACATTATTAATTTCTTCAAATCTCAACCTGCACTCAATTATGGTTTCGCAGAATTA
ACCCAGCCATGGCACCAACCAGTAGATGCCCCTGGCCCGCGGGCAAATCAAGACGCGATGGTTGAGATTATGAAGTACTG
GTTATCGCAAGGTGCCGATGGTTTCCGCGTGGATATGGCGGATTCGCTTGTGAAAAACGACGGCACCTCAAAGCGGGCCA
CGATTGGTATTTGGCAGTCTATGTTGAGCCAAGTTCGCGCCGAGTTTCCTAATGCCATCTTTGTCTCGGAGTGGGGCACG
CCTACTCAAGCGTTTGAGGCGGGCTTTGACGCTGACTTTTACCTCGATTGGCGCGGCAATGGTTACAACCTTTTGGCACG
TAACACGGATACCCCACTGGAGCGGCGCGATGATGCAAGTTTCTTTAACTCTGATTCCGCTACGGGTGCCCAAGAGTTTC
TCGATATGTATTTGCCGCAATGGGAGCGCACCCATGAGGCAGGGCTGTTTAGTTTTATCAGCGGTAACCATGACTGCCCG
CGTCTTGCACCACGCCTGAATGAACAAGAACGCGCGTTGTTCTTCTTGTTCCAGCTCACTATGCCTGGCCTTCCTTTCAT
TTATTACGGGGATGAAATTGGGCTTCCCTATGCGGAGATCCCTACGAAGGAGGGCGGCTATGCGCGCACGGGGTCGCGCA
CCCCCATGTGCTGGGATTCCCAGTTGCCTAACGGCGGTTTTTCGCTTGGCGACGCTCCCCTGTACCTCCCCATGACTGAT
ACATCCCAGAATGTGGCGCAGCAGCGTGAGCGTGCGGATTCGTTGTTCCATCACGTACAAAAGCTCATTCAGTTGCGTTC
TCAGCTGCCAGCTTTAGATGGCTTTGCTGATCTAGAGTTTGATCTTTCTCTCCTAAAGAAGCACCCCAAGGTTATGGTGT
ATCGCCGCACTCATCATCATGGCGACAGCGTGCTTATTGCCCTCAATGCAGGTAACAAGCCGATACGCGTCGAGCTTCAG
CAGCCCCAAGCACATGAGCTTTTCCGTTGTGGTGATGTGACATATCCCGATCTCTCAGATCACAGCGTGGTTGAGTTGGG
TCCTACTTCTGGCGTCATCTTGTCCGTGTAA

Upstream 100 bases:

>100_bases
GTGTGACTAAGACCGACAAATTTTTATAGAGTTACCTGAGCCACACATTGCACTGGAATTTCATTTTTACTACCTGAAAA
TCGCACTTTTAGCGCAACGA

Downstream 100 bases:

>100_bases
CAATGTTGTCTATGGATACTAGAGACCCCCATGCTTGGTGGCGTGACGCTGCCATTTACCAGATTTACCCCAAGTCCTTC
GCTTCGTCGGGTGGACCTAT

Product: putative glycosilase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MHPNCNDIAQPHPLLPMDINRALARNEPICRYFYPHTTTPTTPLVITSYLTTKNTSRELSTIESMTSKSLPTRTTLSSGT
FYQIYPPSFADSNKDGIGDFRGIISRLDYLSDLGITGIWLNACFDSPFKDGGYDVRDYTKVASRYGTHEDLVELFHQAHA
RGIAIILDLVPGHTSEQHPWFQQSAASKYTDFDDRYIWTSHAFEGGAGLAFIGGEHPRNGAYIINFFKSQPALNYGFAEL
TQPWHQPVDAPGPRANQDAMVEIMKYWLSQGADGFRVDMADSLVKNDGTSKRATIGIWQSMLSQVRAEFPNAIFVSEWGT
PTQAFEAGFDADFYLDWRGNGYNLLARNTDTPLERRDDASFFNSDSATGAQEFLDMYLPQWERTHEAGLFSFISGNHDCP
RLAPRLNEQERALFFLFQLTMPGLPFIYYGDEIGLPYAEIPTKEGGYARTGSRTPMCWDSQLPNGGFSLGDAPLYLPMTD
TSQNVAQQRERADSLFHHVQKLIQLRSQLPALDGFADLEFDLSLLKKHPKVMVYRRTHHHGDSVLIALNAGNKPIRVELQ
QPQAHELFRCGDVTYPDLSDHSVVELGPTSGVILSV

Sequences:

>Translated_596_residues
MHPNCNDIAQPHPLLPMDINRALARNEPICRYFYPHTTTPTTPLVITSYLTTKNTSRELSTIESMTSKSLPTRTTLSSGT
FYQIYPPSFADSNKDGIGDFRGIISRLDYLSDLGITGIWLNACFDSPFKDGGYDVRDYTKVASRYGTHEDLVELFHQAHA
RGIAIILDLVPGHTSEQHPWFQQSAASKYTDFDDRYIWTSHAFEGGAGLAFIGGEHPRNGAYIINFFKSQPALNYGFAEL
TQPWHQPVDAPGPRANQDAMVEIMKYWLSQGADGFRVDMADSLVKNDGTSKRATIGIWQSMLSQVRAEFPNAIFVSEWGT
PTQAFEAGFDADFYLDWRGNGYNLLARNTDTPLERRDDASFFNSDSATGAQEFLDMYLPQWERTHEAGLFSFISGNHDCP
RLAPRLNEQERALFFLFQLTMPGLPFIYYGDEIGLPYAEIPTKEGGYARTGSRTPMCWDSQLPNGGFSLGDAPLYLPMTD
TSQNVAQQRERADSLFHHVQKLIQLRSQLPALDGFADLEFDLSLLKKHPKVMVYRRTHHHGDSVLIALNAGNKPIRVELQ
QPQAHELFRCGDVTYPDLSDHSVVELGPTSGVILSV
>Mature_596_residues
MHPNCNDIAQPHPLLPMDINRALARNEPICRYFYPHTTTPTTPLVITSYLTTKNTSRELSTIESMTSKSLPTRTTLSSGT
FYQIYPPSFADSNKDGIGDFRGIISRLDYLSDLGITGIWLNACFDSPFKDGGYDVRDYTKVASRYGTHEDLVELFHQAHA
RGIAIILDLVPGHTSEQHPWFQQSAASKYTDFDDRYIWTSHAFEGGAGLAFIGGEHPRNGAYIINFFKSQPALNYGFAEL
TQPWHQPVDAPGPRANQDAMVEIMKYWLSQGADGFRVDMADSLVKNDGTSKRATIGIWQSMLSQVRAEFPNAIFVSEWGT
PTQAFEAGFDADFYLDWRGNGYNLLARNTDTPLERRDDASFFNSDSATGAQEFLDMYLPQWERTHEAGLFSFISGNHDCP
RLAPRLNEQERALFFLFQLTMPGLPFIYYGDEIGLPYAEIPTKEGGYARTGSRTPMCWDSQLPNGGFSLGDAPLYLPMTD
TSQNVAQQRERADSLFHHVQKLIQLRSQLPALDGFADLEFDLSLLKKHPKVMVYRRTHHHGDSVLIALNAGNKPIRVELQ
QPQAHELFRCGDVTYPDLSDHSVVELGPTSGVILSV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=424, Percent_Identity=29.2452830188679, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI1790687, Length=233, Percent_Identity=35.6223175965665, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1786604, Length=467, Percent_Identity=23.982869379015, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=519, Percent_Identity=25.4335260115607, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25147709, Length=468, Percent_Identity=24.3589743589744, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=225, Percent_Identity=37.7777777777778, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321731, Length=230, Percent_Identity=35.6521739130435, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319776, Length=230, Percent_Identity=35.6521739130435, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321726, Length=222, Percent_Identity=35.1351351351351, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324416, Length=608, Percent_Identity=24.0131578947368, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322241, Length=606, Percent_Identity=23.9273927392739, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322021, Length=606, Percent_Identity=23.9273927392739, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24583745, Length=591, Percent_Identity=29.4416243654822, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24583747, Length=546, Percent_Identity=30.03663003663, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24583749, Length=546, Percent_Identity=30.03663003663, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24586587, Length=527, Percent_Identity=27.8937381404175, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24586593, Length=491, Percent_Identity=28.7169042769857, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24586591, Length=539, Percent_Identity=27.6437847866419, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24586599, Length=614, Percent_Identity=26.2214983713355, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI45549022, Length=564, Percent_Identity=27.6595744680851, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24586589, Length=535, Percent_Identity=26.7289719626168, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI221330053, Length=230, Percent_Identity=36.5217391304348, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24586597, Length=211, Percent_Identity=36.0189573459716, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281360393, Length=439, Percent_Identity=25.7403189066059, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 66890; Mature: 66890

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPNCNDIAQPHPLLPMDINRALARNEPICRYFYPHTTTPTTPLVITSYLTTKNTSRELS
CCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEHHCCCCHHHHH
TIESMTSKSLPTRTTLSSGTFYQIYPPSFADSNKDGIGDFRGIISRLDYLSDLGITGIWL
HHHHHHHCCCCCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEH
NACFDSPFKDGGYDVRDYTKVASRYGTHEDLVELFHQAHARGIAIILDLVPGHTSEQHPW
HHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
FQQSAASKYTDFDDRYIWTSHAFEGGAGLAFIGGEHPRNGAYIINFFKSQPALNYGFAEL
HHHHHHCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCHHHH
TQPWHQPVDAPGPRANQDAMVEIMKYWLSQGADGFRVDMADSLVKNDGTSKRATIGIWQS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHCCCCCCHHHHHHHHH
MLSQVRAEFPNAIFVSEWGTPTQAFEAGFDADFYLDWRGNGYNLLARNTDTPLERRDDAS
HHHHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCH
FFNSDSATGAQEFLDMYLPQWERTHEAGLFSFISGNHDCPRLAPRLNEQERALFFLFQLT
HCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHEEEEEEHH
MPGLPFIYYGDEIGLPYAEIPTKEGGYARTGSRTPMCWDSQLPNGGFSLGDAPLYLPMTD
CCCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECC
TSQNVAQQRERADSLFHHVQKLIQLRSQLPALDGFADLEFDLSLLKKHPKVMVYRRTHHH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCC
GDSVLIALNAGNKPIRVELQQPQAHELFRCGDVTYPDLSDHSVVELGPTSGVILSV
CCEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEC
>Mature Secondary Structure
MHPNCNDIAQPHPLLPMDINRALARNEPICRYFYPHTTTPTTPLVITSYLTTKNTSRELS
CCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEHHCCCCHHHHH
TIESMTSKSLPTRTTLSSGTFYQIYPPSFADSNKDGIGDFRGIISRLDYLSDLGITGIWL
HHHHHHHCCCCCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEH
NACFDSPFKDGGYDVRDYTKVASRYGTHEDLVELFHQAHARGIAIILDLVPGHTSEQHPW
HHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
FQQSAASKYTDFDDRYIWTSHAFEGGAGLAFIGGEHPRNGAYIINFFKSQPALNYGFAEL
HHHHHHCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCHHHH
TQPWHQPVDAPGPRANQDAMVEIMKYWLSQGADGFRVDMADSLVKNDGTSKRATIGIWQS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHCCCCCCHHHHHHHHH
MLSQVRAEFPNAIFVSEWGTPTQAFEAGFDADFYLDWRGNGYNLLARNTDTPLERRDDAS
HHHHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCH
FFNSDSATGAQEFLDMYLPQWERTHEAGLFSFISGNHDCPRLAPRLNEQERALFFLFQLT
HCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHEEEEEEHH
MPGLPFIYYGDEIGLPYAEIPTKEGGYARTGSRTPMCWDSQLPNGGFSLGDAPLYLPMTD
CCCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECC
TSQNVAQQRERADSLFHHVQKLIQLRSQLPALDGFADLEFDLSLLKKHPKVMVYRRTHHH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCC
GDSVLIALNAGNKPIRVELQQPQAHELFRCGDVTYPDLSDHSVVELGPTSGVILSV
CCEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8787404 [H]