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The map label for this gene is dppA [H]

Identifier: 38233124

GI number: 38233124

Start: 484258

End: 485874

Strand: Reverse

Name: dppA [H]

Synonym: DIP0515

Alternate gene names: 38233124

Gene position: 485874-484258 (Counterclockwise)

Preceding gene: 38233131

Following gene: 38233123

Centisome position: 19.52

GC content: 56.59

Gene sequence:

>1617_bases
ATGGATTCACAGCGCCGCTACTCTCGCCGCGATTTCTTTAAGATCTCCGGCGCAGTCGGACTCGCAGCAGGCTTCGCCGC
CACCCTCTCGGCGTGTGCCCCCGATAACAGCGGTTCTTCCACATCCGGCAGTCAAGCAGCAGCCGGATCTGCCAATAACG
ATGGCACCATTAACGCAGCAATCTCTTACGAGTTGGGCACCAATGGTTACGACCCAATGTCCACCACCGCAGCCCTGACA
GTTGCTGCTAACTGGCACACCCTCGAGGGTCTGACCGAAATCGACCCAGCCACGGGCGAAACCTACGCAGCTTTGGCTAA
GGAAATGCCAAAGGCTTCCAGCACCGAGGTAGAGGTCACGCTTCGCGACGGCGCCAAGTTCCACGATGGCAGCGCAGTCA
CCGCCGATGACGTTGTCTTCTCCTTCGAGCGCGTACTAGATAAGGCCAACAAGAGCCTGTACGCCTCCTTCATTCCATTC
ATTACCAGTGTTGAGAAGAAGGACGACAAGACTGTCGTCTTCAAGCTTTCCACCGAGACTGGCGTTTTTGCTAGCCGCCT
TGCTGTGGTCAAGATCGTTCCTAAGGCAGCTGTTGAGAAGGACGTTGACGCATTCTCCGCTAACCCAATCGGTTCCGGCC
CTTACAAGATGACCGACAACGGCGGTACCTCTAAGACCGTGAAGTTCGAGCGCTTCGAGGACTACAACGGCCCTAAGCCA
GCTCGCGCAAAGAACATGGTCTGGCAGATCATCCCAGACGCTTCGACCCGTACCAATGCTTTGCAGTCCAAGTCCGTTCA
GGCTATCGACTCGGTTCCTTACCTCTCCATCGATCAGCTCAAGGGCACCCACACTGTGGAATCCGTTCAGGGCTTCGGCT
TGCTGTTCGCAATGTTCAACAACGACAAGTCCAACCCATTCAGCGACTTGAAGAACCGCCAAGCATTCCTCTACGGCATC
GACATGGACAAGGTCATCAAGACCGCTCTGCTCGGCCAAGCAACCGCACCTACCTCCTTCCTCCACAAGGAGCACCCTCA
GTACCACGAGGCCAAGGTTGTTTACTCACACGATGCAGAAAAGGCAAAGGCTTTGTTCAAGGAGACTGGCCTGACCAAGC
TGCGCATGCTGTGCACCGACCACGACTGGGTTAAGAAGTGCACCCCATTGATCCAGGAATCCCTGACCGCCTTGGGTATT
CAGGTCGACTTCACCGAGAAGAAGTCTTCGGATGTGTACAACACCATCGACGGCAAGCCAGAGGCTTACGACGTTGTGAT
CGCACCTGGCGACCCATCTGTATTCGGCACCGACCCTGACCTGCTCATGCGCTGGTGGTACTCCGGAGACACCTGGACCG
ACACCCGTATGCACTGGAAGGGTACCGAGGCTTACGCCAAGCTTCAGGAGGTTCTCGACGCAGGCCTTGCAGCTACCAGC
GAGTCCGAACAGAAGAACAAGTGGCACGAGGCTCTCGACATCATCTCCGAGAACGTTCCTCTCTACCCACTGTTACACCG
CAAGGCTCCAACCGCGTGGGATGCAAGCACGCTGGTTGACTTCAAGCCGATCTCCCTGACCGGCCTGAGCTTCTCGGGTG
TTGGCACCACTCAGTAG

Upstream 100 bases:

>100_bases
AACACATTTCCACCCCCGACATCAGACGTCTGATGTAGGATGCTTTGTAGATCGACCGTCGATGCTAATTCCTCACTTGG
GAAAGGAAACTCCTATGAGC

Downstream 100 bases:

>100_bases
CACTCAATCTTCCCCCTAGCTCCCAATCTTTTTCCACACATCGCCTAGAGCGGGTCCTAGGGGGAATCCCGCCACCTTTT
ATCTCTTTGCCGGTGGCATA

Product: putative transport system secreted protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MDSQRRYSRRDFFKISGAVGLAAGFAATLSACAPDNSGSSTSGSQAAAGSANNDGTINAAISYELGTNGYDPMSTTAALT
VAANWHTLEGLTEIDPATGETYAALAKEMPKASSTEVEVTLRDGAKFHDGSAVTADDVVFSFERVLDKANKSLYASFIPF
ITSVEKKDDKTVVFKLSTETGVFASRLAVVKIVPKAAVEKDVDAFSANPIGSGPYKMTDNGGTSKTVKFERFEDYNGPKP
ARAKNMVWQIIPDASTRTNALQSKSVQAIDSVPYLSIDQLKGTHTVESVQGFGLLFAMFNNDKSNPFSDLKNRQAFLYGI
DMDKVIKTALLGQATAPTSFLHKEHPQYHEAKVVYSHDAEKAKALFKETGLTKLRMLCTDHDWVKKCTPLIQESLTALGI
QVDFTEKKSSDVYNTIDGKPEAYDVVIAPGDPSVFGTDPDLLMRWWYSGDTWTDTRMHWKGTEAYAKLQEVLDAGLAATS
ESEQKNKWHEALDIISENVPLYPLLHRKAPTAWDASTLVDFKPISLTGLSFSGVGTTQ

Sequences:

>Translated_538_residues
MDSQRRYSRRDFFKISGAVGLAAGFAATLSACAPDNSGSSTSGSQAAAGSANNDGTINAAISYELGTNGYDPMSTTAALT
VAANWHTLEGLTEIDPATGETYAALAKEMPKASSTEVEVTLRDGAKFHDGSAVTADDVVFSFERVLDKANKSLYASFIPF
ITSVEKKDDKTVVFKLSTETGVFASRLAVVKIVPKAAVEKDVDAFSANPIGSGPYKMTDNGGTSKTVKFERFEDYNGPKP
ARAKNMVWQIIPDASTRTNALQSKSVQAIDSVPYLSIDQLKGTHTVESVQGFGLLFAMFNNDKSNPFSDLKNRQAFLYGI
DMDKVIKTALLGQATAPTSFLHKEHPQYHEAKVVYSHDAEKAKALFKETGLTKLRMLCTDHDWVKKCTPLIQESLTALGI
QVDFTEKKSSDVYNTIDGKPEAYDVVIAPGDPSVFGTDPDLLMRWWYSGDTWTDTRMHWKGTEAYAKLQEVLDAGLAATS
ESEQKNKWHEALDIISENVPLYPLLHRKAPTAWDASTLVDFKPISLTGLSFSGVGTTQ
>Mature_538_residues
MDSQRRYSRRDFFKISGAVGLAAGFAATLSACAPDNSGSSTSGSQAAAGSANNDGTINAAISYELGTNGYDPMSTTAALT
VAANWHTLEGLTEIDPATGETYAALAKEMPKASSTEVEVTLRDGAKFHDGSAVTADDVVFSFERVLDKANKSLYASFIPF
ITSVEKKDDKTVVFKLSTETGVFASRLAVVKIVPKAAVEKDVDAFSANPIGSGPYKMTDNGGTSKTVKFERFEDYNGPKP
ARAKNMVWQIIPDASTRTNALQSKSVQAIDSVPYLSIDQLKGTHTVESVQGFGLLFAMFNNDKSNPFSDLKNRQAFLYGI
DMDKVIKTALLGQATAPTSFLHKEHPQYHEAKVVYSHDAEKAKALFKETGLTKLRMLCTDHDWVKKCTPLIQESLTALGI
QVDFTEKKSSDVYNTIDGKPEAYDVVIAPGDPSVFGTDPDLLMRWWYSGDTWTDTRMHWKGTEAYAKLQEVLDAGLAATS
ESEQKNKWHEALDIISENVPLYPLLHRKAPTAWDASTLVDFKPISLTGLSFSGVGTTQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=332, Percent_Identity=29.5180722891566, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787052, Length=429, Percent_Identity=24.9417249417249, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787762, Length=414, Percent_Identity=25.8454106280193, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787551, Length=481, Percent_Identity=22.2453222453222, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789887, Length=350, Percent_Identity=23.7142857142857, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58507; Mature: 58507

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQRRYSRRDFFKISGAVGLAAGFAATLSACAPDNSGSSTSGSQAAAGSANNDGTINAA
CCCHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ISYELGTNGYDPMSTTAALTVAANWHTLEGLTEIDPATGETYAALAKEMPKASSTEVEVT
EEEEECCCCCCCCCCCEEEEEEECCHHHCCCHHCCCCCCHHHHHHHHHCCCCCCCEEEEE
LRDGAKFHDGSAVTADDVVFSFERVLDKANKSLYASFIPFITSVEKKDDKTVVFKLSTET
EECCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GVFASRLAVVKIVPKAAVEKDVDAFSANPIGSGPYKMTDNGGTSKTVKFERFEDYNGPKP
CHHHHHEEHEEECCHHHHHHCCHHHCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCC
ARAKNMVWQIIPDASTRTNALQSKSVQAIDSVPYLSIDQLKGTHTVESVQGFGLLFAMFN
CCHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHCCCEEEEEEEC
NDKSNPFSDLKNRQAFLYGIDMDKVIKTALLGQATAPTSFLHKEHPQYHEAKVVYSHDAE
CCCCCCHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCHH
KAKALFKETGLTKLRMLCTDHDWVKKCTPLIQESLTALGIQVDFTEKKSSDVYNTIDGKP
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHCCCCCC
EAYDVVIAPGDPSVFGTDPDLLMRWWYSGDTWTDTRMHWKGTEAYAKLQEVLDAGLAATS
CEEEEEEECCCCCCCCCCHHHHEEEEECCCCEECCEEEECCHHHHHHHHHHHHHHHCCCC
ESEQKNKWHEALDIISENVPLYPLLHRKAPTAWDASTLVDFKPISLTGLSFSGVGTTQ
CHHHHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCEEEECCCEEECEEECCCCCCC
>Mature Secondary Structure
MDSQRRYSRRDFFKISGAVGLAAGFAATLSACAPDNSGSSTSGSQAAAGSANNDGTINAA
CCCHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ISYELGTNGYDPMSTTAALTVAANWHTLEGLTEIDPATGETYAALAKEMPKASSTEVEVT
EEEEECCCCCCCCCCCEEEEEEECCHHHCCCHHCCCCCCHHHHHHHHHCCCCCCCEEEEE
LRDGAKFHDGSAVTADDVVFSFERVLDKANKSLYASFIPFITSVEKKDDKTVVFKLSTET
EECCCEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GVFASRLAVVKIVPKAAVEKDVDAFSANPIGSGPYKMTDNGGTSKTVKFERFEDYNGPKP
CHHHHHEEHEEECCHHHHHHCCHHHCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCC
ARAKNMVWQIIPDASTRTNALQSKSVQAIDSVPYLSIDQLKGTHTVESVQGFGLLFAMFN
CCHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHCCCEEEEEEEC
NDKSNPFSDLKNRQAFLYGIDMDKVIKTALLGQATAPTSFLHKEHPQYHEAKVVYSHDAE
CCCCCCHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCHH
KAKALFKETGLTKLRMLCTDHDWVKKCTPLIQESLTALGIQVDFTEKKSSDVYNTIDGKP
HHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHCCCCCC
EAYDVVIAPGDPSVFGTDPDLLMRWWYSGDTWTDTRMHWKGTEAYAKLQEVLDAGLAATS
CEEEEEEECCCCCCCCCCHHHHEEEEECCCCEECCEEEECCHHHHHHHHHHHHHHHCCCC
ESEQKNKWHEALDIISENVPLYPLLHRKAPTAWDASTLVDFKPISLTGLSFSGVGTTQ
CHHHHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCEEEECCCEEECEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]