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The map label for this gene is senX3 [H]

Identifier: 38233004

GI number: 38233004

Start: 357293

End: 358447

Strand: Direct

Name: senX3 [H]

Synonym: DIP0390

Alternate gene names: 38233004

Gene position: 357293-358447 (Clockwise)

Preceding gene: 38233003

Following gene: 38233005

Centisome position: 14.36

GC content: 54.29

Gene sequence:

>1155_bases
GTGTACGTCGTTATCGCATTTGTGTTGGGCGTGGTCCTTTCGGGCCTCGCCCTACCTGCGTTGAAATGGGTGCGCGGCCG
TAGTTATCGAACGGCGAAAAAGGGGGATAATAAGGTCACCACTGTGAGCCAGATGCTGCATTTGACGGTGCAGGGCTCGC
CCACGGGTATGGCGGTGATCGACGCTACGGGGGCCGTTTTATTGTCTAATGTACGTTCCCACGAGATGGGGATTGTGCAT
GAGCGCACGCTTAATCCGGATATTTGGGAGCTTGCGCAAGAAGCTTATAAAGACCAAGAGACTCATGCGATTGAGTTGGT
GATCGACGAGCGGCGTAATCGCATTACGTCGGTGCGTGCGGTGGTTAAGCCGCTGACGCTTGTCGACAACCGCTACGTGG
TCATTTACAGCACGGATGAGTCGGAAAACCAGCGCATGGAAGCGGCACGTCGTGACTTTGTGGCTAACGTGTCCCATGAG
CTGAAAACTCCTGTGGGTGGCATGGCGTTGCTGGCGGAGGCCATCACGGAGGCCTCTGATGATCAAGAGCAGGTGGAATA
CTTTGGTAATCGCCTGTACAAAGAGGCCCACCGTCTTGCCGACATGATTAATGAGCTCATCTCGCTGTCCAAGCTGCAAG
GTGCTGAGGCGTTGCCGGATCTAGAGCCGGTGAGTGTGGATCGTGTGATCGACGAGGCACTGGCACGCAATGTGTTGGCC
GCCGATAATGCGGGCATTGAGCTCAACCGTGGCAAACCATGCAATGCGATGGTGATGGGGGATATGACGCTGCTGGTCAC
GGCGGTGTCCAACCTGATTAGCAACGCTATTAATTATTCGCCACAGGGAATGCCCATTTCGGTGGCAACCAAGATTTCGC
GGGATGGCCGTGTTCTTATCCGAGTGATCGATAATGGCATTGGCATTTCAGTGGAGAATCAAAAACGAGTGTTTGAGCGC
TTCTTCCGTGTAGATAAAGCGCGGTCACGTTCTACAGGTGGTACGGGATTAGGGCTTGCGATTGTCAAGCATGTGGCAGC
TAATCACGGTGGCGATGTCACGCTGTGGTCGCGTCCTGGAACCGGTTCCACGTTTACGATCGAGCTTCCGATCTATCATG
AAACTGACACGGGTCGCCGAAAGGATAAGAACTGA

Upstream 100 bases:

>100_bases
GCACGGTGCTCAACCCAGGTGGCACCTACCTTGACCCAGAAGCTGCTGCTGCCGGTGCTGCCGCAGTTGCTGCTCAGGGC
GCTAAGTAGTAGCGAGGCAC

Downstream 100 bases:

>100_bases
TGACCTCTATCTTGTTGGTTGAAGACGAAGAGTCGCTAGCCGATCCCCTCGCGTTCTTGTTGCGCAAGGAAGGTTTTGAT
GTAGTAATCGCCGGTGATGG

Product: putative two component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MYVVIAFVLGVVLSGLALPALKWVRGRSYRTAKKGDNKVTTVSQMLHLTVQGSPTGMAVIDATGAVLLSNVRSHEMGIVH
ERTLNPDIWELAQEAYKDQETHAIELVIDERRNRITSVRAVVKPLTLVDNRYVVIYSTDESENQRMEAARRDFVANVSHE
LKTPVGGMALLAEAITEASDDQEQVEYFGNRLYKEAHRLADMINELISLSKLQGAEALPDLEPVSVDRVIDEALARNVLA
ADNAGIELNRGKPCNAMVMGDMTLLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLIRVIDNGIGISVENQKRVFER
FFRVDKARSRSTGGTGLGLAIVKHVAANHGGDVTLWSRPGTGSTFTIELPIYHETDTGRRKDKN

Sequences:

>Translated_384_residues
MYVVIAFVLGVVLSGLALPALKWVRGRSYRTAKKGDNKVTTVSQMLHLTVQGSPTGMAVIDATGAVLLSNVRSHEMGIVH
ERTLNPDIWELAQEAYKDQETHAIELVIDERRNRITSVRAVVKPLTLVDNRYVVIYSTDESENQRMEAARRDFVANVSHE
LKTPVGGMALLAEAITEASDDQEQVEYFGNRLYKEAHRLADMINELISLSKLQGAEALPDLEPVSVDRVIDEALARNVLA
ADNAGIELNRGKPCNAMVMGDMTLLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLIRVIDNGIGISVENQKRVFER
FFRVDKARSRSTGGTGLGLAIVKHVAANHGGDVTLWSRPGTGSTFTIELPIYHETDTGRRKDKN
>Mature_384_residues
MYVVIAFVLGVVLSGLALPALKWVRGRSYRTAKKGDNKVTTVSQMLHLTVQGSPTGMAVIDATGAVLLSNVRSHEMGIVH
ERTLNPDIWELAQEAYKDQETHAIELVIDERRNRITSVRAVVKPLTLVDNRYVVIYSTDESENQRMEAARRDFVANVSHE
LKTPVGGMALLAEAITEASDDQEQVEYFGNRLYKEAHRLADMINELISLSKLQGAEALPDLEPVSVDRVIDEALARNVLA
ADNAGIELNRGKPCNAMVMGDMTLLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLIRVIDNGIGISVENQKRVFER
FFRVDKARSRSTGGTGLGLAIVKHVAANHGGDVTLWSRPGTGSTFTIELPIYHETDTGRRKDKN

Specific function: Part of the two-component regulatory system senX3/regX3. Phosphorylates regX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to senX3 by the pstSCAB phosphate transporter system [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=269, Percent_Identity=33.0855018587361, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=32.618025751073, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=32.0512820512821, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=30.1652892561983, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=29.9145299145299, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=26.1194029850746, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI145693157, Length=392, Percent_Identity=25.5102040816327, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=30.0429184549356, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.7872340425532, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=28.8288288288288, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=29.126213592233, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=27.5471698113208, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=25.6916996047431, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789403, Length=209, Percent_Identity=27.7511961722488, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=28.5087719298246, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=226, Percent_Identity=29.646017699115, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=306, Percent_Identity=26.1437908496732, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42169; Mature: 42169

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVVIAFVLGVVLSGLALPALKWVRGRSYRTAKKGDNKVTTVSQMLHLTVQGSPTGMAVI
CEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCCEEEE
DATGAVLLSNVRSHEMGIVHERTLNPDIWELAQEAYKDQETHAIELVIDERRNRITSVRA
ECCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
VVKPLTLVDNRYVVIYSTDESENQRMEAARRDFVANVSHELKTPVGGMALLAEAITEASD
HHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DQEQVEYFGNRLYKEAHRLADMINELISLSKLQGAEALPDLEPVSVDRVIDEALARNVLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADNAGIELNRGKPCNAMVMGDMTLLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLI
CCCCCEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEE
RVIDNGIGISVENQKRVFERFFRVDKARSRSTGGTGLGLAIVKHVAANHGGDVTLWSRPG
EEECCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCC
TGSTFTIELPIYHETDTGRRKDKN
CCCEEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MYVVIAFVLGVVLSGLALPALKWVRGRSYRTAKKGDNKVTTVSQMLHLTVQGSPTGMAVI
CEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCCEEEE
DATGAVLLSNVRSHEMGIVHERTLNPDIWELAQEAYKDQETHAIELVIDERRNRITSVRA
ECCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
VVKPLTLVDNRYVVIYSTDESENQRMEAARRDFVANVSHELKTPVGGMALLAEAITEASD
HHHHHHEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DQEQVEYFGNRLYKEAHRLADMINELISLSKLQGAEALPDLEPVSVDRVIDEALARNVLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ADNAGIELNRGKPCNAMVMGDMTLLVTAVSNLISNAINYSPQGMPISVATKISRDGRVLI
CCCCCEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEE
RVIDNGIGISVENQKRVFERFFRVDKARSRSTGGTGLGLAIVKHVAANHGGDVTLWSRPG
EEECCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCC
TGSTFTIELPIYHETDTGRRKDKN
CCCEEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA