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The map label for this gene is regX3 [H]

Identifier: 38233005

GI number: 38233005

Start: 358447

End: 359127

Strand: Direct

Name: regX3 [H]

Synonym: DIP0391

Alternate gene names: 38233005

Gene position: 358447-359127 (Clockwise)

Preceding gene: 38233004

Following gene: 38233007

Centisome position: 14.4

GC content: 57.42

Gene sequence:

>681_bases
ATGACCTCTATCTTGTTGGTTGAAGACGAAGAGTCGCTAGCCGATCCCCTCGCGTTCTTGTTGCGCAAGGAAGGTTTTGA
TGTAGTAATCGCCGGTGATGGCCCCAGCGCCTTGGTGGAGTTTGATCGCAACGCCATCGATATTGTGCTGCTTGACCTCA
TGCTTCCTGGCATGTCGGGTACGGATGTGTGCAAGCGCCTGCGAGCAGTATCCTCAGTCCCCGTGATCATGGTGACGGCA
CGGGACTCGGAGATCGACAAGGTGGTAGGCCTAGAACTCGGTGCCGACGACTACGTGACCAAACCATATTCTTCTCGCGA
GCTCATTGCCCGAATCCGTGCCGTGCTGCGTCGCGGCGGGGAGACAATCGAAGAATCGGATGAGATCCTCGGCAGCGGCC
GAATCCACATGGATGTGGAACGCCACACCGTGACCGTCGACGGCGAAGAGATCTCCATGCCGCTAAAAGAATTCGACCTG
TTGGAATACCTCATGCGCAACTCGGGGCGCGTGCTCACCCGTGGCCAGCTCATCGACCGCGTGTGGGGTGCCGACTACGT
AGGGGATACCAAAACCTTGGATGTGCACATTAAACGCCTGCGCTCCAAGATCGAACCAGAACCCTCCGCGCCATGCCACG
TGATTACTGTGCGCGGTCTGGGCTACAAGTACGAAGACTAG

Upstream 100 bases:

>100_bases
ATGTCACGCTGTGGTCGCGTCCTGGAACCGGTTCCACGTTTACGATCGAGCTTCCGATCTATCATGAAACTGACACGGGT
CGCCGAAAGGATAAGAACTG

Downstream 100 bases:

>100_bases
CTGGGTGCGGGGCTAGCGGGATACCTGCTTTTTGGCGCGCCGCGCAGTGTTGCGCCAACACCTCGTAGGAGGCATCGCCC
ATCAGCGCCCGCAGCTCCGC

Product: putative two component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSGTDVCKRLRAVSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGGETIEESDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDL
LEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYED

Sequences:

>Translated_226_residues
MTSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSGTDVCKRLRAVSSVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGGETIEESDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDL
LEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYED
>Mature_225_residues
TSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSGTDVCKRLRAVSSVPVIMVTAR
DSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGGETIEESDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDLL
EYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYED

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=43.1111111111111, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.6828193832599, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=37.0535714285714, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=37.3873873873874, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.1990950226244, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=37.10407239819, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=37.9464285714286, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.2070484581498, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=34.7826086956522, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=36.3636363636364, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=34.6666666666667, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=36.1990950226244, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.4821428571429, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25127; Mature: 24996

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSG
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHEECCCCHHHHHEEEHHCCCCCH
TDVCKRLRAVSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGG
HHHHHHHHHHCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
ETIEESDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDLLEYLMRNSGRVLTRGQLIDR
CCHHHHHHHHCCCEEEEEEEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
VWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYED
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
TSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSG
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHEECCCCHHHHHEEEHHCCCCCH
TDVCKRLRAVSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGG
HHHHHHHHHHCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
ETIEESDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDLLEYLMRNSGRVLTRGQLIDR
CCHHHHHHHHCCCEEEEEEEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
VWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYED
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA