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The map label for this gene is sdhB [H]

Identifier: 38232988

GI number: 38232988

Start: 340942

End: 341691

Strand: Direct

Name: sdhB [H]

Synonym: DIP0372

Alternate gene names: 38232988

Gene position: 340942-341691 (Clockwise)

Preceding gene: 38232987

Following gene: 38232989

Centisome position: 13.7

GC content: 58.67

Gene sequence:

>750_bases
ATGAAACTCCATCTTGAAATCTGGCGTCAGGCCGGTCCAAACAGCGAAGGTCACTTCGAGCCCATCGACGTCAACGACGC
CGTTCCTCAGATGTCGGTCCTTGAGCTTCTCGACCACGTCAACACTGGCCTGATTGAGGAAGGCAAAGAGCCTTTCGTAT
TCGCCTCCGACTGCCGCGAGGGCATCTGTGGTACCTGTGGCCTTTTGGTCAACGGTCGCCCACATGGACTGGACAAGAAC
AAGCCTTCTTGCCAGCAGCGCCTCGACCACGTCCCAGACGGATCGACCCTGAAGATCGAGCCACTGCGCTCCGCAGCTTA
CCCAGTGGTCAAGGATCTCTTGGTAGACCGCTCCGCACTGGACCGCGTCTTGGAAAAGGGCGGCTTCGTTTCCATCAACG
CCGGCACCGCTCCTGATGCAGACACCCTGCACCAGAACCACGAGTCTGCCGAGTTGGCTCTCGACCACGCAGCCTGCATT
GGCTGTGGTGCTTGTGTGGCTGCTTGCCCTAACGGCGCAGCTCACTTGTTCACCGGTGCAAAGCTGATCCACCTCTCCCT
GATGCCTTTGGGCAAGGAAGAGCGCGGCAAGCGTGCACGCAAGATGGTCGACGAGTTGGAGACAAACTTCGGACACTGCT
CCCTTTACGGTGAGTGCGCGGATGTTTGCCCTGCAGGTATCCCACTGTCCGCAGTTGCGGCAATCAACAAGGAACGTGCT
CGTGCGTTCTTCCGTGGCAAGGACGACTAA

Upstream 100 bases:

>100_bases
TTTCCGCATGGGAGCCAGGTGCAGTCGAGGGCGAGTTCATTCGCCACGCTGAACCACTCACATTCGAAGCGATCCCGCTG
ATGACAAGGAATTACAAGTA

Downstream 100 bases:

>100_bases
TTACCACTGATTACCGTAAGGTAATACTCTAAGTAAACAGACGTTCTTCTACTCGGGTACATAGAAAGGCAAGCACAATG
TCCCATTCCCTAGATGCGAC

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKLHLEIWRQAGPNSEGHFEPIDVNDAVPQMSVLELLDHVNTGLIEEGKEPFVFASDCREGICGTCGLLVNGRPHGLDKN
KPSCQQRLDHVPDGSTLKIEPLRSAAYPVVKDLLVDRSALDRVLEKGGFVSINAGTAPDADTLHQNHESAELALDHAACI
GCGACVAACPNGAAHLFTGAKLIHLSLMPLGKEERGKRARKMVDELETNFGHCSLYGECADVCPAGIPLSAVAAINKERA
RAFFRGKDD

Sequences:

>Translated_249_residues
MKLHLEIWRQAGPNSEGHFEPIDVNDAVPQMSVLELLDHVNTGLIEEGKEPFVFASDCREGICGTCGLLVNGRPHGLDKN
KPSCQQRLDHVPDGSTLKIEPLRSAAYPVVKDLLVDRSALDRVLEKGGFVSINAGTAPDADTLHQNHESAELALDHAACI
GCGACVAACPNGAAHLFTGAKLIHLSLMPLGKEERGKRARKMVDELETNFGHCSLYGECADVCPAGIPLSAVAAINKERA
RAFFRGKDD
>Mature_249_residues
MKLHLEIWRQAGPNSEGHFEPIDVNDAVPQMSVLELLDHVNTGLIEEGKEPFVFASDCREGICGTCGLLVNGRPHGLDKN
KPSCQQRLDHVPDGSTLKIEPLRSAAYPVVKDLLVDRSALDRVLEKGGFVSINAGTAPDADTLHQNHESAELALDHAACI
GCGACVAACPNGAAHLFTGAKLIHLSLMPLGKEERGKRARKMVDELETNFGHCSLYGECADVCPAGIPLSAVAAINKERA
RAFFRGKDD

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790596, Length=248, Percent_Identity=29.8387096774194, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322987, Length=241, Percent_Identity=24.896265560166, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26752; Mature: 26752

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHLEIWRQAGPNSEGHFEPIDVNDAVPQMSVLELLDHVNTGLIEEGKEPFVFASDCRE
CEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEHHHHHC
GICGTCGLLVNGRPHGLDKNKPSCQQRLDHVPDGSTLKIEPLRSAAYPVVKDLLVDRSAL
CCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCHHHH
DRVLEKGGFVSINAGTAPDADTLHQNHESAELALDHAACIGCGACVAACPNGAAHLFTGA
HHHHHCCCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KLIHLSLMPLGKEERGKRARKMVDELETNFGHCSLYGECADVCPAGIPLSAVAAINKERA
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHH
RAFFRGKDD
HHHHCCCCC
>Mature Secondary Structure
MKLHLEIWRQAGPNSEGHFEPIDVNDAVPQMSVLELLDHVNTGLIEEGKEPFVFASDCRE
CEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEHHHHHC
GICGTCGLLVNGRPHGLDKNKPSCQQRLDHVPDGSTLKIEPLRSAAYPVVKDLLVDRSAL
CCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCHHHH
DRVLEKGGFVSINAGTAPDADTLHQNHESAELALDHAACIGCGACVAACPNGAAHLFTGA
HHHHHCCCEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KLIHLSLMPLGKEERGKRARKMVDELETNFGHCSLYGECADVCPAGIPLSAVAAINKERA
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHH
RAFFRGKDD
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]