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The map label for this gene is 38232953

Identifier: 38232953

GI number: 38232953

Start: 302520

End: 304046

Strand: Reverse

Name: 38232953

Synonym: DIP0332

Alternate gene names: NA

Gene position: 304046-302520 (Counterclockwise)

Preceding gene: 38232957

Following gene: 38232951

Centisome position: 12.22

GC content: 57.89

Gene sequence:

>1527_bases
ATGACCAAACTATGGCGCGCCTTCAAGTGGCTGTTTAAGACTTCGTGGCCGTTATACGCAACCACGGTATTGGGCTCCAA
TGTGTTGGGCGCGGTGGGGGTCATGTTGTTCCTGAAGTACTTGGTGCCGCTGCCAGAGTTCGACCAGTTCACCGATGAGG
CCAGCTACCTACCTGAGCTGGGCATTGGTTATTTGATCCTGGCGGTTATTTTTGGTGGCGCGGTCACCTTTTTGCTGTTT
CGTCCGGTGTTGGACTGGCAGCGCCATCCGGATACGCATGATCCAAACATGGTTCGTAATTTGGTGATGCGTATCCCGAT
CTACCAGGCGGCGTTGTGCAGCGTGGTGTGGGCGCTGGGCATTGTGGTGTTGGCGATTGCCGCTGGGCAGACTTCGCCAC
GCTTGGCGTTGGCCATTGCGGTGGCTTCGACGCTTAGTGGTGCTGTGATCGTGGTGCTCACCTACTTGGAGGCGCAACGG
TTGGTGCGGCCGGTGGCGGCAACGGCGTTGGCTCGTCGTTTTGAGGATTCCACGTTGGAGCCGCCGATTACGTCGCGTCT
GCGACTCACATGGGCGTTGACTAGCGCGGTTCCGATCATTGGCATTTTGTTGATGGTGATGGGCCACCACTTAGGCATGT
TTACAGATAATGTCAGCGACATTATGCCTGCGGTCATTGCGTTGGCTATGGCCGCGCTCATTACCGGATTTTTGGGCACC
ACTCTTTCGATCATGAGTGTGGTGGATCCGATTTTGGAGCTGCAGGGGGCGATCAATCGGGTGCGTCGCGGGGATTCGGG
TGTCCAGGTGGACATTTACGACGGCTCCGAGATCGGTGTGCTTCAGGCCGGCTTCAATGAGATGATGCGCGGTTTGAAGG
AGCGCCAGCGTGTGCGCGATATTTTCGGCCGCTATGTGGGTGTAGAGGTTGCCCGGCGCGCTTTGGAGGAGCGTCCGCAA
CTAGGCGGCGAGGATCGTGAGGTTGCCGTTGTGTTCGTTGACGTGATTGGTTCGACCACGTTCGCCGTCAACCATGATCC
AGAAGAGGTTGTGGAGGAGCTCAATCGTTTCTTTGAGCATGTGGTGGAGGTTGTGCACCGCAACAAGGGCATTATTAATA
AGTTCCAAGGCGATGCTGCGCTGGCTGTTTTTGGTGCGCCAGTCACGCTTTCCGACGCCACCGGCCACGCCCTCACCGCC
GCCCGCGAGCTGCGTCAGGAGCTCATGGGCTTGCGCCTTGAGGCCGGTATTGGTGTTGCCTCTGGTCACGTGGTGGCCGG
TCACATTGGTGGTCATGATCGCTTTGAGTACACGGTGATCGGTGACGCTGTGAATACTGCGGCGCGTCTGACGGAGATCG
CCAAGAACACCCCTGGTCGCGTGCTCACCAACTCTGCTACGTTGCAGCGCGCCAACGAGGCGGAACAGGCTCGGTGGACG
ATGATGAAGTCCGTGGAGCTGCGTGGTCGTTCTTTGATGACACAGCTTGCACGGCCTATTCGCCCAACGTTGGCGGATCG
TTCCTAA

Upstream 100 bases:

>100_bases
GCTCACGCCCATCTGCGCAAAGATGTCCGACCCAGTTATTTCCGTGCTCATTACTTCAATAGAGTATCGCTTGTAGTAGC
CGACCGTTAAAGTAGTGGGC

Downstream 100 bases:

>100_bases
TTAGTTAGCGGATTAGTTAGCGAAGGTGCCGCGTGATGTGACCAAGCATGGTCACTCGTGTTGCCACGTCGACGTCTGCG
GGGGCTTGGATCTTGGCACC

Product: putative adenylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTKLWRAFKWLFKTSWPLYATTVLGSNVLGAVGVMLFLKYLVPLPEFDQFTDEASYLPELGIGYLILAVIFGGAVTFLLF
RPVLDWQRHPDTHDPNMVRNLVMRIPIYQAALCSVVWALGIVVLAIAAGQTSPRLALAIAVASTLSGAVIVVLTYLEAQR
LVRPVAATALARRFEDSTLEPPITSRLRLTWALTSAVPIIGILLMVMGHHLGMFTDNVSDIMPAVIALAMAALITGFLGT
TLSIMSVVDPILELQGAINRVRRGDSGVQVDIYDGSEIGVLQAGFNEMMRGLKERQRVRDIFGRYVGVEVARRALEERPQ
LGGEDREVAVVFVDVIGSTTFAVNHDPEEVVEELNRFFEHVVEVVHRNKGIINKFQGDAALAVFGAPVTLSDATGHALTA
ARELRQELMGLRLEAGIGVASGHVVAGHIGGHDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNSATLQRANEAEQARWT
MMKSVELRGRSLMTQLARPIRPTLADRS

Sequences:

>Translated_508_residues
MTKLWRAFKWLFKTSWPLYATTVLGSNVLGAVGVMLFLKYLVPLPEFDQFTDEASYLPELGIGYLILAVIFGGAVTFLLF
RPVLDWQRHPDTHDPNMVRNLVMRIPIYQAALCSVVWALGIVVLAIAAGQTSPRLALAIAVASTLSGAVIVVLTYLEAQR
LVRPVAATALARRFEDSTLEPPITSRLRLTWALTSAVPIIGILLMVMGHHLGMFTDNVSDIMPAVIALAMAALITGFLGT
TLSIMSVVDPILELQGAINRVRRGDSGVQVDIYDGSEIGVLQAGFNEMMRGLKERQRVRDIFGRYVGVEVARRALEERPQ
LGGEDREVAVVFVDVIGSTTFAVNHDPEEVVEELNRFFEHVVEVVHRNKGIINKFQGDAALAVFGAPVTLSDATGHALTA
ARELRQELMGLRLEAGIGVASGHVVAGHIGGHDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNSATLQRANEAEQARWT
MMKSVELRGRSLMTQLARPIRPTLADRS
>Mature_507_residues
TKLWRAFKWLFKTSWPLYATTVLGSNVLGAVGVMLFLKYLVPLPEFDQFTDEASYLPELGIGYLILAVIFGGAVTFLLFR
PVLDWQRHPDTHDPNMVRNLVMRIPIYQAALCSVVWALGIVVLAIAAGQTSPRLALAIAVASTLSGAVIVVLTYLEAQRL
VRPVAATALARRFEDSTLEPPITSRLRLTWALTSAVPIIGILLMVMGHHLGMFTDNVSDIMPAVIALAMAALITGFLGTT
LSIMSVVDPILELQGAINRVRRGDSGVQVDIYDGSEIGVLQAGFNEMMRGLKERQRVRDIFGRYVGVEVARRALEERPQL
GGEDREVAVVFVDVIGSTTFAVNHDPEEVVEELNRFFEHVVEVVHRNKGIINKFQGDAALAVFGAPVTLSDATGHALTAA
RELRQELMGLRLEAGIGVASGHVVAGHIGGHDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNSATLQRANEAEQARWTM
MKSVELRGRSLMTQLARPIRPTLADRS

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 55505; Mature: 55374

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TKLWRAFKWLFKTSWPLYATTVLGSNVLGAVGVMLFLKYLVPLPEFDQFTDEASYLPEL
CHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCC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HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]