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The map label for this gene is 38232951

Identifier: 38232951

GI number: 38232951

Start: 299461

End: 301524

Strand: Reverse

Name: 38232951

Synonym: DIP0330

Alternate gene names: NA

Gene position: 301524-299461 (Counterclockwise)

Preceding gene: 38232953

Following gene: 38232950

Centisome position: 12.12

GC content: 60.95

Gene sequence:

>2064_bases
GTGACCAACACCCTTGAAAGTAACCCCATGACCACCACAACCGGCGCACTCACCATCACTTTCGCCACCACCTGCGACGG
GCCACTCGCCCACATCCCCCACCACCTCGACCTCAACATCATCCACGGACGCATCCAAGGCACCACCGCCCACCGCCGCA
TCGACGCCGAAGACCCCGACGGGCTTGACGACGGCCTCCCGCACCACCTATGCCTCAGCGTGGACACCACCGGAACCCAC
CTCTTTATCGACGGCTACGAGGCATTTTCCACCACCCAAACCGAATGGTTCGACACCTCAGAACTCACTCTCAACCCCCA
CGGCGACCTCACCATCATCGATCACCAAATCCTCAACCACGCCCCCACCCCACGGCAAGCGCGCAACCTCGCACCGGCAG
CCGAACCCCTCGTCTGGTTCGCCGGCAGCCACCTCAGCACCCGCGACACCCAGCGCATATCACACCTCACCCACGGCTCG
CTGCGGCTACTTATGAAAACCCGCGGCACCGGCCAAGGTGGCGTGGCCTTCCAAGCACACACCATCAATGGCGACCTCAC
CCTCGAAATCATTGACGGCACCCTCATATTCAGCGTGCGATGCCACGACGAAGACTACGTGCGCATCACCGCGCCGGGGC
GCTGGGATGACGGCCACATTTACGACGTCGTCATCGTGTGCGGGCGCGGAGCCACCGACATCTACGTCGACGGCCAGCAA
CTCATCCACAGCCCAGGGGCCGCCTTCTTTAATGACCTGTCAGGTGAGCTCTCCGTCCACATTGGTACCTCCGCCAGCGG
TGTGCGCCTTTTCGGCGAGGTGCAATCGGGAATGATCTACCCCCACGTGTTCAACCATCACCAAGTCCAGCGCCTCGCCA
CTGTCGAACCGATAGCCACCCAAGCGCTATTCGACTGCCTCCTCGACGGGGCACAAAGCTACCGCATTCCCTCGCTGATA
ACCACGGATTCCGGTGTCATTATCGCCGGCGCCGACAAGCGCGTAAGTATTGCTAACGACGCCCCCAACGACATCGACTT
CGTACTACGCCGAAGCGTGGATGGCGGCCGCACATGGCAACCGCCACGCACAATCCTGCAGCTCCCCGACACCGCCTGCG
TTACCGACTCCGTCCTGCTCCAAGACCACACTACCGGCCGTATTTTCGCCTTTCTTGACCAATTCCCCGCAGGGATCGGC
CAACCCAACGCCGCCTTCGGCACCGGCTTCGACGCAGACGGCAACCGCATTGGACACTTTGCCGACGGCAGCACCTGCAC
CATGCCACGTGAGGTGGATCAGCTGGAGGCGTCGTTTTTCAGCGATCCCCACACCGCACCCCCAGGCATCGTTTTTCAAC
ACCCCAGCTGCCACTTATGGATGCTCACCAGCGACGACGACGGCCTCAGTTGGAGCACCCCACGCGATCTGACCCCAGAT
GTCAAAGAAGAATGGATGCGCTTTTGTGGCACCTCGCCAGGAAACGGCATCCAGCTACAACGCGGCACCCATGCTGGTCG
ACTCCTTATCCCGATGTACTACACCAAAGGCGACCAGTTCTTCGCCGCCGCACTCTACAGCGACGACCACGGCGACACTT
GGCATCGCGGCGAATCCCCCGACCTCGAGATGTATGAATCCACGCTGGTAGAGGCAAGCGACGGCAGCGTGCTGCTCTGG
GCACGCAACCAGCACCCCTCCGGTGCGGTGGCTCATGCACGCAGCACCGACGGCGGCCACTCGTGGTCACAGGTCACGTT
CAACCCGAACGTTCCAGAGATCTTCTCCCAGCCCAACGCGCTGCGCGTGACCAACCCCGATGGCATCATCTTTGCCAACG
CCTCTCAATTGTTGCCGTTTCGTGGACGCGGTGTGCTCCGCATGTCTACTAACGACGGCGCCTCTTGGCAGCACAATCGC
GTGTTTAATCCTCGACACTACGTGTATCAGTGCATGACCCAGCTTCCCGACGGTTCCATCGGTCTATTGTGGGAACGCGA
AATGCAGGGACTGTTTTTCAGCATCATTCCCATGACATGGATCATGCAAGGCTATGCCCTTTAA

Upstream 100 bases:

>100_bases
GACTAGTGGTGTGGTGTTCATGGTTTTCCCCTTGCAAAAGTGCGGTGGCATCGTAACAATTATGAGCGTACTCCAGACGT
CAGACGTCTGATCCCAAAGA

Downstream 100 bases:

>100_bases
AAAGGTCACAATTTTCTTTTCAAATATTCTGCACATACGCTAATAAAGTTCATTGCTTTTCCTCGTTCCGAGAGAGGATC
CTCGTCGTGTCTCAACCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Neuraminidase [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MTNTLESNPMTTTTGALTITFATTCDGPLAHIPHHLDLNIIHGRIQGTTAHRRIDAEDPDGLDDGLPHHLCLSVDTTGTH
LFIDGYEAFSTTQTEWFDTSELTLNPHGDLTIIDHQILNHAPTPRQARNLAPAAEPLVWFAGSHLSTRDTQRISHLTHGS
LRLLMKTRGTGQGGVAFQAHTINGDLTLEIIDGTLIFSVRCHDEDYVRITAPGRWDDGHIYDVVIVCGRGATDIYVDGQQ
LIHSPGAAFFNDLSGELSVHIGTSASGVRLFGEVQSGMIYPHVFNHHQVQRLATVEPIATQALFDCLLDGAQSYRIPSLI
TTDSGVIIAGADKRVSIANDAPNDIDFVLRRSVDGGRTWQPPRTILQLPDTACVTDSVLLQDHTTGRIFAFLDQFPAGIG
QPNAAFGTGFDADGNRIGHFADGSTCTMPREVDQLEASFFSDPHTAPPGIVFQHPSCHLWMLTSDDDGLSWSTPRDLTPD
VKEEWMRFCGTSPGNGIQLQRGTHAGRLLIPMYYTKGDQFFAAALYSDDHGDTWHRGESPDLEMYESTLVEASDGSVLLW
ARNQHPSGAVAHARSTDGGHSWSQVTFNPNVPEIFSQPNALRVTNPDGIIFANASQLLPFRGRGVLRMSTNDGASWQHNR
VFNPRHYVYQCMTQLPDGSIGLLWEREMQGLFFSIIPMTWIMQGYAL

Sequences:

>Translated_687_residues
MTNTLESNPMTTTTGALTITFATTCDGPLAHIPHHLDLNIIHGRIQGTTAHRRIDAEDPDGLDDGLPHHLCLSVDTTGTH
LFIDGYEAFSTTQTEWFDTSELTLNPHGDLTIIDHQILNHAPTPRQARNLAPAAEPLVWFAGSHLSTRDTQRISHLTHGS
LRLLMKTRGTGQGGVAFQAHTINGDLTLEIIDGTLIFSVRCHDEDYVRITAPGRWDDGHIYDVVIVCGRGATDIYVDGQQ
LIHSPGAAFFNDLSGELSVHIGTSASGVRLFGEVQSGMIYPHVFNHHQVQRLATVEPIATQALFDCLLDGAQSYRIPSLI
TTDSGVIIAGADKRVSIANDAPNDIDFVLRRSVDGGRTWQPPRTILQLPDTACVTDSVLLQDHTTGRIFAFLDQFPAGIG
QPNAAFGTGFDADGNRIGHFADGSTCTMPREVDQLEASFFSDPHTAPPGIVFQHPSCHLWMLTSDDDGLSWSTPRDLTPD
VKEEWMRFCGTSPGNGIQLQRGTHAGRLLIPMYYTKGDQFFAAALYSDDHGDTWHRGESPDLEMYESTLVEASDGSVLLW
ARNQHPSGAVAHARSTDGGHSWSQVTFNPNVPEIFSQPNALRVTNPDGIIFANASQLLPFRGRGVLRMSTNDGASWQHNR
VFNPRHYVYQCMTQLPDGSIGLLWEREMQGLFFSIIPMTWIMQGYAL
>Mature_686_residues
TNTLESNPMTTTTGALTITFATTCDGPLAHIPHHLDLNIIHGRIQGTTAHRRIDAEDPDGLDDGLPHHLCLSVDTTGTHL
FIDGYEAFSTTQTEWFDTSELTLNPHGDLTIIDHQILNHAPTPRQARNLAPAAEPLVWFAGSHLSTRDTQRISHLTHGSL
RLLMKTRGTGQGGVAFQAHTINGDLTLEIIDGTLIFSVRCHDEDYVRITAPGRWDDGHIYDVVIVCGRGATDIYVDGQQL
IHSPGAAFFNDLSGELSVHIGTSASGVRLFGEVQSGMIYPHVFNHHQVQRLATVEPIATQALFDCLLDGAQSYRIPSLIT
TDSGVIIAGADKRVSIANDAPNDIDFVLRRSVDGGRTWQPPRTILQLPDTACVTDSVLLQDHTTGRIFAFLDQFPAGIGQ
PNAAFGTGFDADGNRIGHFADGSTCTMPREVDQLEASFFSDPHTAPPGIVFQHPSCHLWMLTSDDDGLSWSTPRDLTPDV
KEEWMRFCGTSPGNGIQLQRGTHAGRLLIPMYYTKGDQFFAAALYSDDHGDTWHRGESPDLEMYESTLVEASDGSVLLWA
RNQHPSGAVAHARSTDGGHSWSQVTFNPNVPEIFSQPNALRVTNPDGIIFANASQLLPFRGRGVLRMSTNDGASWQHNRV
FNPRHYVYQCMTQLPDGSIGLLWEREMQGLFFSIIPMTWIMQGYAL

Specific function: Sialidases have been suggested to be pathogenic factors in microbial infections [H]

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 F5/8 type C domain [H]

Homologues:

Organism=Homo sapiens, GI4557791, Length=198, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR000421
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR008979
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF00754 F5_F8_type_C; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 75481; Mature: 75350

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLESNPMTTTTGALTITFATTCDGPLAHIPHHLDLNIIHGRIQGTTAHRRIDAEDPD
CCCCCCCCCCEEECCEEEEEEEECCCCCHHHCCCCEEEEEEEEEEECCHHHEEECCCCCC
GLDDGLPHHLCLSVDTTGTHLFIDGYEAFSTTQTEWFDTSELTLNPHGDLTIIDHQILNH
CCCCCCCCEEEEEEECCCCEEEEECCHHCCCCCCCEECCCEEEECCCCCEEEEEHHHHCC
APTPRQARNLAPAAEPLVWFAGSHLSTRDTQRISHLTHGSLRLLMKTRGTGQGGVAFQAH
CCCCHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEE
TINGDLTLEIIDGTLIFSVRCHDEDYVRITAPGRWDDGHIYDVVIVCGRGATDIYVDGQQ
EECCEEEEEEECCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEECCHH
LIHSPGAAFFNDLSGELSVHIGTSASGVRLFGEVQSGMIYPHVFNHHQVQRLATVEPIAT
HHCCCCHHHHHCCCCEEEEEECCCCCCEEEEEEHHCCEEEEEECCCHHHHHHHHCCHHHH
QALFDCLLDGAQSYRIPSLITTDSGVIIAGADKRVSIANDAPNDIDFVLRRSVDGGRTWQ
HHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCHHHHEEECCCCCCCCC
PPRTILQLPDTACVTDSVLLQDHTTGRIFAFLDQFPAGIGQPNAAFGTGFDADGNRIGHF
CCHHHEECCCCHHCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
ADGSTCTMPREVDQLEASFFSDPHTAPPGIVFQHPSCHLWMLTSDDDGLSWSTPRDLTPD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCH
VKEEWMRFCGTSPGNGIQLQRGTHAGRLLIPMYYTKGDQFFAAALYSDDHGDTWHRGESP
HHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCC
DLEMYESTLVEASDGSVLLWARNQHPSGAVAHARSTDGGHSWSQVTFNPNVPEIFSQPNA
CHHHHHHHEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHCCCCE
LRVTNPDGIIFANASQLLPFRGRGVLRMSTNDGASWQHNRVFNPRHYVYQCMTQLPDGSI
EEEECCCCEEEECHHHCCEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
GLLWEREMQGLFFSIIPMTWIMQGYAL
EEEEHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNTLESNPMTTTTGALTITFATTCDGPLAHIPHHLDLNIIHGRIQGTTAHRRIDAEDPD
CCCCCCCCCEEECCEEEEEEEECCCCCHHHCCCCEEEEEEEEEEECCHHHEEECCCCCC
GLDDGLPHHLCLSVDTTGTHLFIDGYEAFSTTQTEWFDTSELTLNPHGDLTIIDHQILNH
CCCCCCCCEEEEEEECCCCEEEEECCHHCCCCCCCEECCCEEEECCCCCEEEEEHHHHCC
APTPRQARNLAPAAEPLVWFAGSHLSTRDTQRISHLTHGSLRLLMKTRGTGQGGVAFQAH
CCCCHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEE
TINGDLTLEIIDGTLIFSVRCHDEDYVRITAPGRWDDGHIYDVVIVCGRGATDIYVDGQQ
EECCEEEEEEECCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEECCHH
LIHSPGAAFFNDLSGELSVHIGTSASGVRLFGEVQSGMIYPHVFNHHQVQRLATVEPIAT
HHCCCCHHHHHCCCCEEEEEECCCCCCEEEEEEHHCCEEEEEECCCHHHHHHHHCCHHHH
QALFDCLLDGAQSYRIPSLITTDSGVIIAGADKRVSIANDAPNDIDFVLRRSVDGGRTWQ
HHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCHHHHEEECCCCCCCCC
PPRTILQLPDTACVTDSVLLQDHTTGRIFAFLDQFPAGIGQPNAAFGTGFDADGNRIGHF
CCHHHEECCCCHHCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
ADGSTCTMPREVDQLEASFFSDPHTAPPGIVFQHPSCHLWMLTSDDDGLSWSTPRDLTPD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCH
VKEEWMRFCGTSPGNGIQLQRGTHAGRLLIPMYYTKGDQFFAAALYSDDHGDTWHRGESP
HHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCC
DLEMYESTLVEASDGSVLLWARNQHPSGAVAHARSTDGGHSWSQVTFNPNVPEIFSQPNA
CHHHHHHHEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHCCCCE
LRVTNPDGIIFANASQLLPFRGRGVLRMSTNDGASWQHNRVFNPRHYVYQCMTQLPDGSI
EEEECCCCEEEECHHHCCEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
GLLWEREMQGLFFSIIPMTWIMQGYAL
EEEEHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034213 [H]