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The map label for this gene is cat [H]

Identifier: 38232902

GI number: 38232902

Start: 247748

End: 249286

Strand: Direct

Name: cat [H]

Synonym: DIP0281

Alternate gene names: 38232902

Gene position: 247748-249286 (Clockwise)

Preceding gene: 38232900

Following gene: 38232915

Centisome position: 9.96

GC content: 60.43

Gene sequence:

>1539_bases
GTGACCAGCCCAGTCGATCCAATCCTGAACAAGGGCGAGCGCACCGAAGCAGCTCCTCACACCACCCGCGCCGGCGGGCA
GCCCGTCGCCAGCGAAAACATCTCCATCACCGCAGGCCCACAAGGCGCCAACGTACTCAACGACCTGCACCTGATCGAAA
AACTCGCACACTTTAACCGCGAGCGCGTCCCAGAGCGCAATCCACACGCCAAAGGTCACGGCGCATTCGGCGAACTCCAC
ATCACCGAAGACGTATCCCAGTACACCAAGGCCAAGCTCTTCCAAAAAGGCACCGTCACCCCCATGGCCGTGCGCTTTTC
TACCGTCGCCGGTGAAAAAGGCTCCCCAGACACCTGGCGCGACGTCCACGGCTTCGCACTGCGCTTTTACACCCAAGACG
GCAACTACGACATCGTAGGAAACAACACCCCAACCTTCTTCCTACGCGACGCCATGAAGTTCCCCGACTTCATCCACTCC
CAGAAGCGCCTCGGCTCCAGCGGCCTGCGCGATGCTGACATGCAATGGGACTTCTGGACCCGCACCCCAGAATCCGCACA
CCAAGTCACCTACCTCATGGGCGACCGCGGCACACCAAAAACCAGCCGCCACCAGGACGGATTTGGCTCTCACACCTACC
AGTGGATCAACGAAGACGGCCAGCCAGTGTGGGTGAAGTACCACTTTAAGACCCGCCAGGGCTGGGAAACCTTCACCGAC
GCAGAGGCCCAAGAAATGGCCGGCAAGAACGCCGACTACCAGCGCGAAGACCTCTACAATGCCATCGAGCGCGGCGACTT
CCCCATCTGGGACGTCAAAGTCCAGATCATGCCATTCGACGAGGCCGAAACCTACCGCTGGAACCCCTTCGACCTGACCA
AGACCTGGTCCCAGAAGGACTACCCGCTTATCGACGTCGGCTACTTCGTGCTCAACCGCAACCCACAGAACTTCTTCGCC
CAGATCGAACAGCTGGCCCTCGACCCAGCCAACCTCGTCCCAGGCGTTGGACTCTCCCCAGACCGCATGCTCATGGCCCG
TGCCTTCGCCTACGCAGACGCACAACGCTACCGCATTGGCCCGAACTACCAGCAGCTGCCCATCAACCAGCCAGTGGTAC
CGGTGAACACCTACCAGCACGAAGGCCCCATGGCCTACCACTTCAACCCAGCTGACGCGCCGGTGCACACACCAAACCGC
TTTGGCAAGGGTGCCGGCTACCTCGACGACGGTCAAACCTCGTCCTCCGGTGCGACCTACGGTCAGGCGCAGGATCTCTA
CGTCAACCCAGATCCACACGGCACCGACCTGACTCGCGCAGCCTATGTCAAGCACGCAGACGATGACGACTTCATGCAAG
CCGGAATCCTCTACCGCGAGGTCTATGACGACGCAGCCAAGGAACGCTTCGTGGACAACGTGACCAATGCCATGGCAGGG
GTATCCCCAGAAACCGAGGAGCGCGTCTACTGGTACTGGACCCAAGTAGACGAAAACCTCGGTGCGAAAATCCGTGAGGC
ATTCGCCGCTAAGAAGTAG

Upstream 100 bases:

>100_bases
AGGTAATACCTAACAAAAAAAGTTCATTGCTAGGGTTTGCTTTTTAATGTAAGCTATTAATCGACTCACATTTGATAGGA
AACCCTTAAGGAGGGACATC

Downstream 100 bases:

>100_bases
CAGGCAGCACCCACATTTTCTCGGGGTCGCAGTGGATGAGGACTTCGTCGCCAAGCGCGGCGAAGGCAAGCTCGTCGTCA
GGCGAACAATGCAACACAAT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MTSPVDPILNKGERTEAAPHTTRAGGQPVASENISITAGPQGANVLNDLHLIEKLAHFNRERVPERNPHAKGHGAFGELH
ITEDVSQYTKAKLFQKGTVTPMAVRFSTVAGEKGSPDTWRDVHGFALRFYTQDGNYDIVGNNTPTFFLRDAMKFPDFIHS
QKRLGSSGLRDADMQWDFWTRTPESAHQVTYLMGDRGTPKTSRHQDGFGSHTYQWINEDGQPVWVKYHFKTRQGWETFTD
AEAQEMAGKNADYQREDLYNAIERGDFPIWDVKVQIMPFDEAETYRWNPFDLTKTWSQKDYPLIDVGYFVLNRNPQNFFA
QIEQLALDPANLVPGVGLSPDRMLMARAFAYADAQRYRIGPNYQQLPINQPVVPVNTYQHEGPMAYHFNPADAPVHTPNR
FGKGAGYLDDGQTSSSGATYGQAQDLYVNPDPHGTDLTRAAYVKHADDDDFMQAGILYREVYDDAAKERFVDNVTNAMAG
VSPETEERVYWYWTQVDENLGAKIREAFAAKK

Sequences:

>Translated_512_residues
MTSPVDPILNKGERTEAAPHTTRAGGQPVASENISITAGPQGANVLNDLHLIEKLAHFNRERVPERNPHAKGHGAFGELH
ITEDVSQYTKAKLFQKGTVTPMAVRFSTVAGEKGSPDTWRDVHGFALRFYTQDGNYDIVGNNTPTFFLRDAMKFPDFIHS
QKRLGSSGLRDADMQWDFWTRTPESAHQVTYLMGDRGTPKTSRHQDGFGSHTYQWINEDGQPVWVKYHFKTRQGWETFTD
AEAQEMAGKNADYQREDLYNAIERGDFPIWDVKVQIMPFDEAETYRWNPFDLTKTWSQKDYPLIDVGYFVLNRNPQNFFA
QIEQLALDPANLVPGVGLSPDRMLMARAFAYADAQRYRIGPNYQQLPINQPVVPVNTYQHEGPMAYHFNPADAPVHTPNR
FGKGAGYLDDGQTSSSGATYGQAQDLYVNPDPHGTDLTRAAYVKHADDDDFMQAGILYREVYDDAAKERFVDNVTNAMAG
VSPETEERVYWYWTQVDENLGAKIREAFAAKK
>Mature_511_residues
TSPVDPILNKGERTEAAPHTTRAGGQPVASENISITAGPQGANVLNDLHLIEKLAHFNRERVPERNPHAKGHGAFGELHI
TEDVSQYTKAKLFQKGTVTPMAVRFSTVAGEKGSPDTWRDVHGFALRFYTQDGNYDIVGNNTPTFFLRDAMKFPDFIHSQ
KRLGSSGLRDADMQWDFWTRTPESAHQVTYLMGDRGTPKTSRHQDGFGSHTYQWINEDGQPVWVKYHFKTRQGWETFTDA
EAQEMAGKNADYQREDLYNAIERGDFPIWDVKVQIMPFDEAETYRWNPFDLTKTWSQKDYPLIDVGYFVLNRNPQNFFAQ
IEQLALDPANLVPGVGLSPDRMLMARAFAYADAQRYRIGPNYQQLPINQPVVPVNTYQHEGPMAYHFNPADAPVHTPNRF
GKGAGYLDDGQTSSSGATYGQAQDLYVNPDPHGTDLTRAAYVKHADDDDFMQAGILYREVYDDAAKERFVDNVTNAMAGV
SPETEERVYWYWTQVDENLGAKIREAFAAKK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=486, Percent_Identity=44.0329218106996, Blast_Score=435, Evalue=1e-122,
Organism=Escherichia coli, GI48994891, Length=375, Percent_Identity=41.0666666666667, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71998444, Length=505, Percent_Identity=42.3762376237624, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25147792, Length=512, Percent_Identity=41.6015625, Blast_Score=413, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI25151141, Length=497, Percent_Identity=42.2535211267606, Blast_Score=413, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6320462, Length=501, Percent_Identity=41.5169660678643, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321525, Length=510, Percent_Identity=38.4313725490196, Blast_Score=334, Evalue=2e-92,
Organism=Drosophila melanogaster, GI17981717, Length=504, Percent_Identity=44.047619047619, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI19920968, Length=500, Percent_Identity=39.8, Blast_Score=386, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57952; Mature: 57820

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPVDPILNKGERTEAAPHTTRAGGQPVASENISITAGPQGANVLNDLHLIEKLAHFNR
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
ERVPERNPHAKGHGAFGELHITEDVSQYTKAKLFQKGTVTPMAVRFSTVAGEKGSPDTWR
HCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHH
DVHGFALRFYTQDGNYDIVGNNTPTFFLRDAMKFPDFIHSQKRLGSSGLRDADMQWDFWT
HCCEEEEEEEEECCCEEEECCCCCCEEEHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEEC
RTPESAHQVTYLMGDRGTPKTSRHQDGFGSHTYQWINEDGQPVWVKYHFKTRQGWETFTD
CCCCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEEEECCCCCCHHCC
AEAQEMAGKNADYQREDLYNAIERGDFPIWDVKVQIMPFDEAETYRWNPFDLTKTWSQKD
CHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEECCCCCCCCCCCCCC
YPLIDVGYFVLNRNPQNFFAQIEQLALDPANLVPGVGLSPDRMLMARAFAYADAQRYRIG
CCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHEECC
PNYQQLPINQPVVPVNTYQHEGPMAYHFNPADAPVHTPNRFGKGAGYLDDGQTSSSGATY
CCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GQAQDLYVNPDPHGTDLTRAAYVKHADDDDFMQAGILYREVYDDAAKERFVDNVTNAMAG
CCCCCEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSPETEERVYWYWTQVDENLGAKIREAFAAKK
CCCCCCCEEEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPVDPILNKGERTEAAPHTTRAGGQPVASENISITAGPQGANVLNDLHLIEKLAHFNR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
ERVPERNPHAKGHGAFGELHITEDVSQYTKAKLFQKGTVTPMAVRFSTVAGEKGSPDTWR
HCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHH
DVHGFALRFYTQDGNYDIVGNNTPTFFLRDAMKFPDFIHSQKRLGSSGLRDADMQWDFWT
HCCEEEEEEEEECCCEEEECCCCCCEEEHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEEC
RTPESAHQVTYLMGDRGTPKTSRHQDGFGSHTYQWINEDGQPVWVKYHFKTRQGWETFTD
CCCCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEEEECCCCCCHHCC
AEAQEMAGKNADYQREDLYNAIERGDFPIWDVKVQIMPFDEAETYRWNPFDLTKTWSQKD
CHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEECCCCCCCCCCCCCC
YPLIDVGYFVLNRNPQNFFAQIEQLALDPANLVPGVGLSPDRMLMARAFAYADAQRYRIG
CCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHEECC
PNYQQLPINQPVVPVNTYQHEGPMAYHFNPADAPVHTPNRFGKGAGYLDDGQTSSSGATY
CCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GQAQDLYVNPDPHGTDLTRAAYVKHADDDDFMQAGILYREVYDDAAKERFVDNVTNAMAG
CCCCCEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSPETEERVYWYWTQVDENLGAKIREAFAAKK
CCCCCCCEEEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]