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The map label for this gene is sigC [H]

Identifier: 38232901

GI number: 38232901

Start: 247054

End: 247620

Strand: Reverse

Name: sigC [H]

Synonym: DIP0280

Alternate gene names: 38232901

Gene position: 247620-247054 (Counterclockwise)

Preceding gene: 38232903

Following gene: 38232897

Centisome position: 9.95

GC content: 64.9

Gene sequence:

>567_bases
ATGAACATGAAACCCTCCGAGCGTGATGATGATTACGTCACAGCCCTAGCCCTCAAGGCTGGCCGTGGCGATCGCGCCGC
TTTGACCGCCTTCATACGCGCCACCCAAACCGACGTATGGAGGCTGTTGGCCCACCTCGGAGGCACCGACATCGCCGACG
ATCTCACCCAAGAGACCTACCTACGCGTCATGAGCGCACTCCCCCGCTTTGCGGCCCGCTCCTCCGCGCGCACATGGCTG
CTCTCCCTCGCCCGACGCGTGTGGGTAGATAACATCCGCCACGACATGGCCCGCCCCCGCAAATCCGCCGCCGAGGTGGA
ACAATGCGACGGCACCACGTCGAGTCTGTGGGCGGAGTGGGTCGACGTTCGCATGCTTATCGACGCCCTCCCCGCGGAGC
GCCGAGAAGCCCTGATCCTCACCCAAGTCTTGGGCTTCTCCTACGAGGAGGCCGCCAAAATTGCCGACGTTCGCATCGGC
ACGATTCGTTCCCGCGTGGCCCGCGCCCGCGCTGATATCGTCGCAGCCGCAGCCACGGAAACCGACACCAACGAGGCAGC
GGGCTAA

Upstream 100 bases:

>100_bases
AAATGTGAGTCGATTAATAGCTTACATTAAAAAGCAAACCCTAGCAATGAACTTTTTTTGTTAGGTATTACCTACAACTA
AAGGTGGAGTGCTAGAGTTC

Downstream 100 bases:

>100_bases
CCGCTATTAGACCAAAAGCTCAGCAATCTGGATGGCGTTGAGTGCAGCGCCCTTGCGTAGATTGTCGCCGGAGACAACAA
AGACGAGGCCCTTGTTGTCG

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MNMKPSERDDDYVTALALKAGRGDRAALTAFIRATQTDVWRLLAHLGGTDIADDLTQETYLRVMSALPRFAARSSARTWL
LSLARRVWVDNIRHDMARPRKSAAEVEQCDGTTSSLWAEWVDVRMLIDALPAERREALILTQVLGFSYEEAAKIADVRIG
TIRSRVARARADIVAAAATETDTNEAAG

Sequences:

>Translated_188_residues
MNMKPSERDDDYVTALALKAGRGDRAALTAFIRATQTDVWRLLAHLGGTDIADDLTQETYLRVMSALPRFAARSSARTWL
LSLARRVWVDNIRHDMARPRKSAAEVEQCDGTTSSLWAEWVDVRMLIDALPAERREALILTQVLGFSYEEAAKIADVRIG
TIRSRVARARADIVAAAATETDTNEAAG
>Mature_188_residues
MNMKPSERDDDYVTALALKAGRGDRAALTAFIRATQTDVWRLLAHLGGTDIADDLTQETYLRVMSALPRFAARSSARTWL
LSLARRVWVDNIRHDMARPRKSAAEVEQCDGTTSSLWAEWVDVRMLIDALPAERREALILTQVLGFSYEEAAKIADVRIG
TIRSRVARARADIVAAAATETDTNEAAG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=174, Percent_Identity=27.0114942528736, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20802; Mature: 20802

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMKPSERDDDYVTALALKAGRGDRAALTAFIRATQTDVWRLLAHLGGTDIADDLTQETY
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRVMSALPRFAARSSARTWLLSLARRVWVDNIRHDMARPRKSAAEVEQCDGTTSSLWAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHH
VDVRMLIDALPAERREALILTQVLGFSYEEAAKIADVRIGTIRSRVARARADIVAAAATE
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TDTNEAAG
CCCCCCCC
>Mature Secondary Structure
MNMKPSERDDDYVTALALKAGRGDRAALTAFIRATQTDVWRLLAHLGGTDIADDLTQETY
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRVMSALPRFAARSSARTWLLSLARRVWVDNIRHDMARPRKSAAEVEQCDGTTSSLWAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHH
VDVRMLIDALPAERREALILTQVLGFSYEEAAKIADVRIGTIRSRVARARADIVAAAATE
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TDTNEAAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]