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The map label for this gene is frp [H]

Identifier: 38232888

GI number: 38232888

Start: 227743

End: 228507

Strand: Reverse

Name: frp [H]

Synonym: DIP0265

Alternate gene names: 38232888

Gene position: 228507-227743 (Counterclockwise)

Preceding gene: 161598679

Following gene: 38232887

Centisome position: 9.18

GC content: 57.12

Gene sequence:

>765_bases
ATGAAGGCAAGCATGAACGAGACGATTCGCACCCAGCTTAACCACCGCACTATCCGTGAGTTCAGCACCGAGCAAGTATC
GGAGGAGATCATGGAGCAGCTGTTTGCGGTGGCGGGGCGGACTGCCACCTCGTTGGGAATGCAAAGCACCAGCATTATCC
GTGTAACTGACCCCCAGTTGCGGGTACGCTTAGCCGAAATCGGCGCCCAGGAATATGTTGGCCGTGCCCCCATCTACCTG
CTGTTTATTGTCGATTGCCACCGCAACGCAGGCATCCTCCAAGAGCTAGGCGCGGACCCTGCCGGTGCTGCGACAGCCCG
CAACTTTGTCCAGGGGTTCACCGATGCCTGCCTCACGGCACAAAACGTGTGCATCGCTGCCGAATCGATGGGCTTAGGTG
TGAACTTCCTCGGCAACGTCCACAACGATGCTGCGGCTGTGATCGAACTGCTGCAACTACCTGAGCTCACTTTCCCAGTT
GTGGGCATGACACTGGGCTGGCCTAATCAAGAGCCGCAACTTAAACCACGTATGGCCACCCCATTGCGCACAATGGAAAA
TGGTTACCATGCGCCCGACTCGTGGCTGGAAGCGCTTAGTGACTACGACCAAGAGATGACCACCTACTACGATCTTCGGG
ATGCCAACCGGCGCGTAGATAGTTTCACCCGTCAGGTGCTCGCAAAAAATCCTGCTGCCGGAGCCGACTCCGATAAACGC
AATCACACCTTCGCGATCGCCCGCGACCAAGGGTTTAACCTCTAG

Upstream 100 bases:

>100_bases
CCTACGCTTCCCTGAAGGCAATTACTTCTGCGGTCAACCGTGCGCTGAGTTAAATAACTACTTACACTTGGCGGACATGA
AAGCAGGCACTAAAGCAGGC

Downstream 100 bases:

>100_bases
GATTTGAATGTTTCCCTGCCCACAAGACCGCCAGCTAGACTGTTCCCCATGACTAATAAGGACCAAGAAGAGCGCGATAA
GGCGCGGGCACAGCGCGCCG

Product: putative nitroreductase

Products: NA

Alternate protein names: Flavin reductase P; NADPH-FMN oxidoreductase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKASMNETIRTQLNHRTIREFSTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQLRVRLAEIGAQEYVGRAPIYL
LFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTAQNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPV
VGMTLGWPNQEPQLKPRMATPLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPAAGADSDKR
NHTFAIARDQGFNL

Sequences:

>Translated_254_residues
MKASMNETIRTQLNHRTIREFSTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQLRVRLAEIGAQEYVGRAPIYL
LFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTAQNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPV
VGMTLGWPNQEPQLKPRMATPLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPAAGADSDKR
NHTFAIARDQGFNL
>Mature_254_residues
MKASMNETIRTQLNHRTIREFSTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQLRVRLAEIGAQEYVGRAPIYL
LFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTAQNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPV
VGMTLGWPNQEPQLKPRMATPLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPAAGADSDKR
NHTFAIARDQGFNL

Specific function: Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=223, Percent_Identity=36.322869955157, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28091; Mature: 28091

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASMNETIRTQLNHRTIREFSTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECHHH
RVRLAEIGAQEYVGRAPIYLLFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTA
HHHHHHHCHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPVVGMTLGWPNQEPQLKPRMAT
HHHEEEHHCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCCCCHHH
PLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPAAGADSDKR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NHTFAIARDQGFNL
CCEEEEECCCCCCC
>Mature Secondary Structure
MKASMNETIRTQLNHRTIREFSTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECHHH
RVRLAEIGAQEYVGRAPIYLLFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTA
HHHHHHHCHHHHHCCCCEEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPVVGMTLGWPNQEPQLKPRMAT
HHHEEEHHCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCCCCHHH
PLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPAAGADSDKR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NHTFAIARDQGFNL
CCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8206832; 8885832 [H]