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The map label for this gene is pdxS [H]

Identifier: 38232853

GI number: 38232853

Start: 194078

End: 194971

Strand: Direct

Name: pdxS [H]

Synonym: DIP0227

Alternate gene names: 38232853

Gene position: 194078-194971 (Clockwise)

Preceding gene: 38232851

Following gene: 38232854

Centisome position: 7.8

GC content: 57.38

Gene sequence:

>894_bases
ATGACTCAAGAAACTTTTACTGCAACTACACGTGTGAAGCGCGGCCTGGCCGACATGCTCAAGGGCGGTGTGATCATGGA
CGTGGTCACCCCAGAACAGGCTCGCATTGCTGAGGATGCCGGCGCTTCTGCTGTGATGGCGTTGGAGCGTGTACCTGCGG
ATATTCGTGCGCAGGGTGGTGTGGCTCGTATGTCGGATCCTGATTTGATCGAGGGCATTGTTAATGCTGTGTCGATCCCG
GTGATGGCTAAGGCTCGTATTGGCCACTTTGTGGAGGCTCAGATTTTGGAGTCTTTGGGTGTGGACTTTATCGACGAGTC
CGAGGTGCTGTCGCCTGCGGATTATGTGAACCACATTGATAAGTGGAACTTCGATGTGCCTTTCGTGTGCGGTGCTACCA
ACTTGGGTGAGGCGTTACGACGCATCACCGAGGGCGCTGCCATGATCCGCTCTAAGGGTGAGGCCGGCACTGGCGACGTT
TCCGAGGCTGTGAAGCACCTGCGCACCATCCGTGGTGAGATCAACCGTTTGCGCAGCATGGATGAGGATCAGCTCTATGT
TGCTGCTAAGGAGATTCAGGCTCCTTATGACCTTGTCCGCGAAGTTGCTGCAACCGGTAAGCTGCCTGTCACCCTCTTTG
TTGCTGGTGGCGTGGCCACGCCTGCCGACGCTGCCTTGGTGATGCAGATGGGTGCCGAGGGCGTGTTCGTGGGATCGGGC
ATTTTCAAGTCCGGTAACCCTGCTGCGCGTGCTGCTGCGATCGTGAAGGCCACCACCATGTATGACGATCCTGCTGCTAT
CGCAGAGGTGTCTCGCGGCCTAGGCGAGGCAATGGTCGGCATTAACGTTGCCGATGTTCCTGCACCTCACCGCTTGGCTG
AGCGCGGATGGTAA

Upstream 100 bases:

>100_bases
CGGGGCGCATAGAGGTATTGTGATGTGCAAAAGTGGTCTATTGCAACATGCTTAATTTGGATCTAGTGTTAGTCCACTTT
TATAGGCTTGGATGTTCACT

Downstream 100 bases:

>100_bases
TCGGAGTACTCACCCTCCAGGGTGGGTTTGCAGAACACATTGCGATCCTAGAGTCCTTGGGTGTGGAGCACCGTCGGGTG
CGCGTGCCCAATGACCTGCT

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGGVARMSDPDLIEGIVNAVSIP
VMAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHIDKWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDV
SEAVKHLRTIRGEINRLRSMDEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSG
IFKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW

Sequences:

>Translated_297_residues
MTQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGGVARMSDPDLIEGIVNAVSIP
VMAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHIDKWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDV
SEAVKHLRTIRGEINRLRSMDEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSG
IFKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW
>Mature_296_residues
TQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGGVARMSDPDLIEGIVNAVSIPV
MAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHIDKWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVS
EAVKHLRTIRGEINRLRSMDEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSGI
FKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring [H]

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=301, Percent_Identity=62.4584717607973, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321049, Length=294, Percent_Identity=64.6258503401361, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6323996, Length=294, Percent_Identity=64.2857142857143, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852 [H]

Pfam domain/function: PF01680 SOR_SNZ [H]

EC number: NA

Molecular weight: Translated: 31340; Mature: 31209

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01235 PDXS_SNZ_1 ; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGG
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCHHHHCCCC
VARMSDPDLIEGIVNAVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHID
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
KWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSEAVKHLRTIRGEINRLRSM
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSG
CCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCC
IFKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCC
>Mature Secondary Structure 
TQETFTATTRVKRGLADMLKGGVIMDVVTPEQARIAEDAGASAVMALERVPADIRAQGG
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCHHHHCCCC
VARMSDPDLIEGIVNAVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLSPADYVNHID
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
KWNFDVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSEAVKHLRTIRGEINRLRSM
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DEDQLYVAAKEIQAPYDLVREVAATGKLPVTLFVAGGVATPADAALVMQMGAEGVFVGSG
CCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCC
IFKSGNPAARAAAIVKATTMYDDPAAIAEVSRGLGEAMVGINVADVPAPHRLAERGW
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]