Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 38232698

GI number: 38232698

Start: 56540

End: 57667

Strand: Reverse

Name: baeS [H]

Synonym: DIP0063

Alternate gene names: 38232698

Gene position: 57667-56540 (Counterclockwise)

Preceding gene: 38232699

Following gene: 38232697

Centisome position: 2.32

GC content: 65.87

Gene sequence:

>1128_bases
ATGAATCCCGGACCCGGCCTGACCTTCCGCTTCCTGGCTGCCCAGGTGTTGGTCGTGGTAATTAGCCTGATGGTGGCCGC
GGCCGTGGCCACGATGGTGGGCCCGACCCTGTTCCATGATCATATGTTGATGGCCGGCCGGGAGGACCCCTCGCTGGGGC
TGTTCCATGCCGAGCAGGCCTACCGGGACGCCAACCTGATCACCCTGGCTGTCGCCCTGCCCACTGCCTTGATCAGCGCC
CTACTGGCCAGCCTGTGGTTATCGCGTCGTCTGCGCACCCCCCTGCAGGATCTCACCCGCGCCGCTACCAGCCTGGCGGC
CGGTAACTCCCGTATCCGCGTGCCCGCCGGAGGAGCAGGCCCCGAGGTCGCCACCCTGGCACATGCCTTCAACACCATGG
CCGACCGGCTGGAACACACCGAACAGGTCCGCCGCCAGATGCTCTCTGATCTGGCCCACGAAATGGGCACCCCCCTATCG
GTGCTCACGGCCTACCTCGATGGTCTCCAGGACGGGGTCGTGGACTGGAATAATGCCAACCACACGATCATGGCTGACCA
ACTCACCCGCCTGACCCGGTTGATGGAAGACATTGACTATGTCTCCCGGGCCCAGGAACACCGGATCGATTTGGACCTGG
CAGAGGAAGGGCTCGGGGATCTGCTCCATACCGCCGCTGCTGCCGCGGGGGAAGCTTATGCTGACAAAGGCGTCGATTTA
CAGGTTGAGACCATTACGGACACCGCCCGGGTGGTCGTGGACCGGCAACGCTTCGGCCAGGTGATGAGCAATCTCCTGTC
GAACGCGCTACGGCACACCCCGGTCGGCGGGCAGGTCCGGATCAGCGTCCACCGACAGGGGGCGTCCACCGCGCTCATCC
ACGTCGCCGATGACGGCGAGGGCATCCCACCTGGCCAGCTCGGACACATCTTCGAACGCTTCTACCGGGGAGATGCCGCC
CGCAGCCGGGACAACGGCGGGTCCGGTATCGGTCTGACCATCTCCAAGGCATTGATCGAGGCCCACGGCGGCACTCTCAC
CGCCACCTCCCCCGGACCCGGTCGCGGAGCGGTGTTTACCCTCCGCCTCCCGCTGTCCCCTCCCGACAGTGAGGAGGCTG
CTCGGTGA

Upstream 100 bases:

>100_bases
ATGTCCACATAGGCAACTTGCGTCGCAAGCTCGGCACCGACACCCGGGGCCGGGGGTTTATCGACACCGTGCGTGGCGTG
GGCTACCGGATGGGGCAGCC

Downstream 100 bases:

>100_bases
CCACACCCTGCCCCGCGTGAGGGCCATGCCCTCCACCCCTCGAAAATATACCCCAGGGGGTATGTGTTAGAGCGTAGCAT
CGTCACATCCCCACCGACCC

Product: putative two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNPGPGLTFRFLAAQVLVVVISLMVAAAVATMVGPTLFHDHMLMAGREDPSLGLFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLAAGNSRIRVPAGGAGPEVATLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTAYLDGLQDGVVDWNNANHTIMADQLTRLTRLMEDIDYVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTARVVVDRQRFGQVMSNLLSNALRHTPVGGQVRISVHRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGSGIGLTISKALIEAHGGTLTATSPGPGRGAVFTLRLPLSPPDSEEAAR

Sequences:

>Translated_375_residues
MNPGPGLTFRFLAAQVLVVVISLMVAAAVATMVGPTLFHDHMLMAGREDPSLGLFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLAAGNSRIRVPAGGAGPEVATLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTAYLDGLQDGVVDWNNANHTIMADQLTRLTRLMEDIDYVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTARVVVDRQRFGQVMSNLLSNALRHTPVGGQVRISVHRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGSGIGLTISKALIEAHGGTLTATSPGPGRGAVFTLRLPLSPPDSEEAAR
>Mature_375_residues
MNPGPGLTFRFLAAQVLVVVISLMVAAAVATMVGPTLFHDHMLMAGREDPSLGLFHAEQAYRDANLITLAVALPTALISA
LLASLWLSRRLRTPLQDLTRAATSLAAGNSRIRVPAGGAGPEVATLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLS
VLTAYLDGLQDGVVDWNNANHTIMADQLTRLTRLMEDIDYVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
QVETITDTARVVVDRQRFGQVMSNLLSNALRHTPVGGQVRISVHRQGASTALIHVADDGEGIPPGQLGHIFERFYRGDAA
RSRDNGGSGIGLTISKALIEAHGGTLTATSPGPGRGAVFTLRLPLSPPDSEEAAR

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=36.3309352517986, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786783, Length=282, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787894, Length=305, Percent_Identity=30.8196721311475, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=30.6382978723404, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788279, Length=308, Percent_Identity=25.974025974026, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=30.1075268817204, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=30.672268907563, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=112, Percent_Identity=46.4285714285714, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=28.1938325991189, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787374, Length=274, Percent_Identity=28.1021897810219, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=24.5762711864407, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=300, Percent_Identity=25.6666666666667, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=314, Percent_Identity=23.8853503184713, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=295, Percent_Identity=28.4745762711864, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=306, Percent_Identity=29.7385620915033, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39966; Mature: 39966

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGPGLTFRFLAAQVLVVVISLMVAAAVATMVGPTLFHDHMLMAGREDPSLGLFHAEQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
YRDANLITLAVALPTALISALLASLWLSRRLRTPLQDLTRAATSLAAGNSRIRVPAGGAG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCC
PEVATLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLSVLTAYLDGLQDGVVDWNNAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCC
HTIMADQLTRLTRLMEDIDYVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
QVETITDTARVVVDRQRFGQVMSNLLSNALRHTPVGGQVRISVHRQGASTALIHVADDGE
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCC
GIPPGQLGHIFERFYRGDAARSRDNGGSGIGLTISKALIEAHGGTLTATSPGPGRGAVFT
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
LRLPLSPPDSEEAAR
EEECCCCCCCCCCCC
>Mature Secondary Structure
MNPGPGLTFRFLAAQVLVVVISLMVAAAVATMVGPTLFHDHMLMAGREDPSLGLFHAEQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
YRDANLITLAVALPTALISALLASLWLSRRLRTPLQDLTRAATSLAAGNSRIRVPAGGAG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCC
PEVATLAHAFNTMADRLEHTEQVRRQMLSDLAHEMGTPLSVLTAYLDGLQDGVVDWNNAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCC
HTIMADQLTRLTRLMEDIDYVSRAQEHRIDLDLAEEGLGDLLHTAAAAAGEAYADKGVDL
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
QVETITDTARVVVDRQRFGQVMSNLLSNALRHTPVGGQVRISVHRQGASTALIHVADDGE
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCC
GIPPGQLGHIFERFYRGDAARSRDNGGSGIGLTISKALIEAHGGTLTATSPGPGRGAVFT
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
LRLPLSPPDSEEAAR
EEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]