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The map label for this gene is fabF [H]

Identifier: 21674927

GI number: 21674927

Start: 2003745

End: 2004986

Strand: Direct

Name: fabF [H]

Synonym: CT2118

Alternate gene names: 21674927

Gene position: 2003745-2004986 (Clockwise)

Preceding gene: 21674926

Following gene: 21674928

Centisome position: 92.98

GC content: 60.47

Gene sequence:

>1242_bases
ATGAAAAGAGTCGTCGTCACCGGAATCGGGGTTCTGTCGCCAATCGGCCTTTCGGCTGGGGCATTCTGGAACGCCCTCAT
GGAGGGAAAAAGCGGCGCTGCACCGATCACCTATTTCGATACGACCAATTTCGCGACCACCTTCGCCTGCGAGCTCAAGA
ATTTCAAGGCCGATGAGTACATCGACCGGAAATCCGCGGATCGCATGGATCCATACTGTCAGTACGGCGTTATCTCTGCC
GAACAGGCGCTGAAAGATTCCGGGCTTGACCTGACCGCGATCGATCCGACCAGGATCGGCGTCGTGCACGGCTCGGGCAT
CGGCGGCATGACGGTCTACGACCAGCAGTTTCGCCAGTATCTGGAACGCGGCCCCCGCAGGGTCAGCCCGTTCTTCATTC
CGATGCTCATTCCCGACATCGCCGCCGGACAGATTTCGATCCGCAACGGTCTGATGGGGCCAAACTATGCGACAGCATCC
GCCTGCGCGACCTCCCTGCACGCTATCATGGACGCCGTCATGCTCCTGCAGATGGGCATGGCCGACTACATGGTCTGCGG
CGGCTCGGAAGCACCGATCACGCAGATGAGCGTGGCTGGCTTCAACTCGGCCAAAGCGCTCTCGACCCGCAACGACGCTC
CGACAAAAGCCTCACGCCCGTACGATGTGGATCGCGACGGTTTCGTCATGGGTGAAGGCGCCGGTTCGCTGGTGATCGAA
ACCTACGAGTCGGCTGTGAAGCGCGGCGCAAAAATCTACGCAGAGATCGTCGGCATGGGCGCGTCTGCCGATGCGTATCA
CCTCACCGCTCCGCACCCGGAGGGTCTTGGCGCTTGCAGCGCGATGACCACCGCCCTGAACATGGCGGGCATCACCCCGG
ACAAGATCGACTACATCAACACCCACGGCACCGCCACGCCGCTTGGCGATCTGGCGGAAATCAAGGCAATCAAGAAGGTG
TTCGGCGAGCACGCATCAAAACTCAGCATCAGCTCGACCAAGTCGATGACCGGTCACCTGCTTGGTGCGGCGGGCGTGGT
CGAATCGATCGCCTGCATCCTTGCGCTGCAGAACCAGACCGTTCCTCCAACCATCAACCTCGACAATGTCGATCCCGAGA
TCGATGTGGATGTGACGCCGAACGTCCCGAAACAGCGCTCGATTGAGTATGCGCTGAACAACGGTTTCGGATTCGGCGGG
CACAACGGCTGCCTGATCTTCAGGAAGGCTCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GACTACATCGTCAACAAGAAAGTAAGCTAAAAGCATTCTCTTCGGGCAGGGCTTGGCCCTGCCTAAAACCAACGTTAAAT
CTGAACAGATGGATCTGGAA

Downstream 100 bases:

>100_bases
CCGGGAATGGCTCGACGATGGCGCACCTGTGGCAAAAACTGATGTCACTTCAGTTCCTTCGTTCAGAAGCGTCCGACGGT
GCCGGTGAAACTTCGGACGC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKRVVVTGIGVLSPIGLSAGAFWNALMEGKSGAAPITYFDTTNFATTFACELKNFKADEYIDRKSADRMDPYCQYGVISA
EQALKDSGLDLTAIDPTRIGVVHGSGIGGMTVYDQQFRQYLERGPRRVSPFFIPMLIPDIAAGQISIRNGLMGPNYATAS
ACATSLHAIMDAVMLLQMGMADYMVCGGSEAPITQMSVAGFNSAKALSTRNDAPTKASRPYDVDRDGFVMGEGAGSLVIE
TYESAVKRGAKIYAEIVGMGASADAYHLTAPHPEGLGACSAMTTALNMAGITPDKIDYINTHGTATPLGDLAEIKAIKKV
FGEHASKLSISSTKSMTGHLLGAAGVVESIACILALQNQTVPPTINLDNVDPEIDVDVTPNVPKQRSIEYALNNGFGFGG
HNGCLIFRKAPAA

Sequences:

>Translated_413_residues
MKRVVVTGIGVLSPIGLSAGAFWNALMEGKSGAAPITYFDTTNFATTFACELKNFKADEYIDRKSADRMDPYCQYGVISA
EQALKDSGLDLTAIDPTRIGVVHGSGIGGMTVYDQQFRQYLERGPRRVSPFFIPMLIPDIAAGQISIRNGLMGPNYATAS
ACATSLHAIMDAVMLLQMGMADYMVCGGSEAPITQMSVAGFNSAKALSTRNDAPTKASRPYDVDRDGFVMGEGAGSLVIE
TYESAVKRGAKIYAEIVGMGASADAYHLTAPHPEGLGACSAMTTALNMAGITPDKIDYINTHGTATPLGDLAEIKAIKKV
FGEHASKLSISSTKSMTGHLLGAAGVVESIACILALQNQTVPPTINLDNVDPEIDVDVTPNVPKQRSIEYALNNGFGFGG
HNGCLIFRKAPAA
>Mature_413_residues
MKRVVVTGIGVLSPIGLSAGAFWNALMEGKSGAAPITYFDTTNFATTFACELKNFKADEYIDRKSADRMDPYCQYGVISA
EQALKDSGLDLTAIDPTRIGVVHGSGIGGMTVYDQQFRQYLERGPRRVSPFFIPMLIPDIAAGQISIRNGLMGPNYATAS
ACATSLHAIMDAVMLLQMGMADYMVCGGSEAPITQMSVAGFNSAKALSTRNDAPTKASRPYDVDRDGFVMGEGAGSLVIE
TYESAVKRGAKIYAEIVGMGASADAYHLTAPHPEGLGACSAMTTALNMAGITPDKIDYINTHGTATPLGDLAEIKAIKKV
FGEHASKLSISSTKSMTGHLLGAAGVVESIACILALQNQTVPPTINLDNVDPEIDVDVTPNVPKQRSIEYALNNGFGFGG
HNGCLIFRKAPAA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=414, Percent_Identity=43.2367149758454, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI223972627, Length=165, Percent_Identity=48.4848484848485, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI41872631, Length=424, Percent_Identity=24.7641509433962, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787337, Length=409, Percent_Identity=53.0562347188264, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1788663, Length=417, Percent_Identity=40.0479616306954, Blast_Score=255, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=32.8502415458937, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=38.3720930232558, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI212642053, Length=360, Percent_Identity=25.8333333333333, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=409, Percent_Identity=25.4278728606357, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=37.4164810690423, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24644341, Length=413, Percent_Identity=41.6464891041162, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI19920632, Length=371, Percent_Identity=24.7978436657682, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330659, Length=371, Percent_Identity=24.7978436657682, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581345, Length=358, Percent_Identity=23.1843575418994, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43592; Mature: 43592

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVVVTGIGVLSPIGLSAGAFWNALMEGKSGAAPITYFDTTNFATTFACELKNFKADEY
CCEEEEECCCHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHH
IDRKSADRMDPYCQYGVISAEQALKDSGLDLTAIDPTRIGVVHGSGIGGMTVYDQQFRQY
HHHCCCCCCCCHHHCCCCCHHHHHHHCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHH
LERGPRRVSPFFIPMLIPDIAAGQISIRNGLMGPNYATASACATSLHAIMDAVMLLQMGM
HHCCCCCCCCEEHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ADYMVCGGSEAPITQMSVAGFNSAKALSTRNDAPTKASRPYDVDRDGFVMGEGAGSLVIE
HHEEEECCCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEHH
TYESAVKRGAKIYAEIVGMGASADAYHLTAPHPEGLGACSAMTTALNMAGITPDKIDYIN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
THGTATPLGDLAEIKAIKKVFGEHASKLSISSTKSMTGHLLGAAGVVESIACILALQNQT
CCCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPPTINLDNVDPEIDVDVTPNVPKQRSIEYALNNGFGFGGHNGCLIFRKAPAA
CCCEEEECCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKRVVVTGIGVLSPIGLSAGAFWNALMEGKSGAAPITYFDTTNFATTFACELKNFKADEY
CCEEEEECCCHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHH
IDRKSADRMDPYCQYGVISAEQALKDSGLDLTAIDPTRIGVVHGSGIGGMTVYDQQFRQY
HHHCCCCCCCCHHHCCCCCHHHHHHHCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHH
LERGPRRVSPFFIPMLIPDIAAGQISIRNGLMGPNYATASACATSLHAIMDAVMLLQMGM
HHCCCCCCCCEEHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ADYMVCGGSEAPITQMSVAGFNSAKALSTRNDAPTKASRPYDVDRDGFVMGEGAGSLVIE
HHEEEECCCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEHH
TYESAVKRGAKIYAEIVGMGASADAYHLTAPHPEGLGACSAMTTALNMAGITPDKIDYIN
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
THGTATPLGDLAEIKAIKKVFGEHASKLSISSTKSMTGHLLGAAGVVESIACILALQNQT
CCCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPPTINLDNVDPEIDVDVTPNVPKQRSIEYALNNGFGFGGHNGCLIFRKAPAA
CCCEEEECCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA