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The map label for this gene is adcA [H]

Identifier: 21674915

GI number: 21674915

Start: 1994676

End: 1995710

Strand: Reverse

Name: adcA [H]

Synonym: CT2106

Alternate gene names: 21674915

Gene position: 1995710-1994676 (Counterclockwise)

Preceding gene: 21674916

Following gene: 21674914

Centisome position: 92.61

GC content: 57.87

Gene sequence:

>1035_bases
ATGATGGGGAAGCCTGACCCTCTCCAACGTTTTGGATTCTCTGCTGTTATTCTTTTTTTACAAAAGAGACACTTTTTTCC
ATCAACCGGGAATCCAGACATGACGACCAGACAAAGCCGCTTCATCTCTTCTTTTTTTTATCCCATCCGACCTCTTGTCC
TCCTGTTGTTGCTGTTCATACCATTGCTGAATGGATGCGCCGGCAAAACAGAGTCGGACAAGTTGCAGGTCGTGGCCTCC
ATCGAGCCGCTGGCGTGGTTCGCGGAGCGCATCGGCGGTGACAGGGTGTCAGTTTCGGTTATGGTGCCTTCCGGGGGCAA
TCCACACACCTATGAGCCGACGCCGAAGCAGATGGCCCAGGTCAGCCATGCGGCGCTTTTCGTGAAGGCTGGTTCGGGCG
TCGAGTTCGAACTTGACTGGATGCCGCGCCTCGTCGATCTCAACAAAAGCATGACGGTGTGCAACGCTTCCGAAGGAGTG
ACGTTGCTGCCGATGAGCGCGGAGAAGTACGAGCATGCGGTGCCTGCCGAGGAGCATCACGATCACGGCAATTTCGATCC
ACACTTTTGGCTTTCGCCAGCGAACGCCAGGCTAATCGCCAAGAACGTCGAACGCTCGCTGGCGGCGATTGATCCGGCAG
GGAAGGAGTATTATGCGGCCAACGCTGCGGCGCTTGACAGGGAGCTTCAGGCTCTCGACAGCGAGATTCGCAAGCAACTC
AGCGTTGTGAAGAACCGTCGCTTCCTCGTTTTCCACCCGGCATGGGGCTATTTCGCCCACGAGTACGGTTTGGAGCAGAT
CGCTGCCGAGGAGGAGGGCAAGACGCTGACGCCGCGCCAGATGGAGCGGGTGATCGGCGAGGCGCGGAGTGCGGGTATCC
GGGTGGTATTTGTTTCGCCGCAGTTCAGCTCGGCGCAGGCCGATGCGATTGCCGGTGATATTGGAGGCCAAACCGTGACG
GTCGATCCGCTCGCGCACGACTACGCGGCCAATCTTCGCAAGGCGACTGCCGCATTTGTCCAGAGCATGCAATGA

Upstream 100 bases:

>100_bases
CGGTATCGACTCGAACATCAGCCTTGCCTCCATCAAGGCCATCGTCAGTGCGCTGAACCGCTACAAAAAGGCTTGATCGT
TTTTTTCGTCAGGCTTCCCG

Downstream 100 bases:

>100_bases
GCGAACCGTTAATCGTTTGCGAGCAGCTCTGCGTCAATCTCGGCGGCGCAAAAATCTTGCAGGGTCTTTCTCTTTCGGTA
TACGAGGGGGACTTTCTTGC

Product: adhesion protein, putative

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MMGKPDPLQRFGFSAVILFLQKRHFFPSTGNPDMTTRQSRFISSFFYPIRPLVLLLLLFIPLLNGCAGKTESDKLQVVAS
IEPLAWFAERIGGDRVSVSVMVPSGGNPHTYEPTPKQMAQVSHAALFVKAGSGVEFELDWMPRLVDLNKSMTVCNASEGV
TLLPMSAEKYEHAVPAEEHHDHGNFDPHFWLSPANARLIAKNVERSLAAIDPAGKEYYAANAAALDRELQALDSEIRKQL
SVVKNRRFLVFHPAWGYFAHEYGLEQIAAEEEGKTLTPRQMERVIGEARSAGIRVVFVSPQFSSAQADAIAGDIGGQTVT
VDPLAHDYAANLRKATAAFVQSMQ

Sequences:

>Translated_344_residues
MMGKPDPLQRFGFSAVILFLQKRHFFPSTGNPDMTTRQSRFISSFFYPIRPLVLLLLLFIPLLNGCAGKTESDKLQVVAS
IEPLAWFAERIGGDRVSVSVMVPSGGNPHTYEPTPKQMAQVSHAALFVKAGSGVEFELDWMPRLVDLNKSMTVCNASEGV
TLLPMSAEKYEHAVPAEEHHDHGNFDPHFWLSPANARLIAKNVERSLAAIDPAGKEYYAANAAALDRELQALDSEIRKQL
SVVKNRRFLVFHPAWGYFAHEYGLEQIAAEEEGKTLTPRQMERVIGEARSAGIRVVFVSPQFSSAQADAIAGDIGGQTVT
VDPLAHDYAANLRKATAAFVQSMQ
>Mature_344_residues
MMGKPDPLQRFGFSAVILFLQKRHFFPSTGNPDMTTRQSRFISSFFYPIRPLVLLLLLFIPLLNGCAGKTESDKLQVVAS
IEPLAWFAERIGGDRVSVSVMVPSGGNPHTYEPTPKQMAQVSHAALFVKAGSGVEFELDWMPRLVDLNKSMTVCNASEGV
TLLPMSAEKYEHAVPAEEHHDHGNFDPHFWLSPANARLIAKNVERSLAAIDPAGKEYYAANAAALDRELQALDSEIRKQL
SVVKNRRFLVFHPAWGYFAHEYGLEQIAAEEEGKTLTPRQMERVIGEARSAGIRVVFVSPQFSSAQADAIAGDIGGQTVT
VDPLAHDYAANLRKATAAFVQSMQ

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=265, Percent_Identity=25.6603773584906, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 37925; Mature: 37925

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGKPDPLQRFGFSAVILFLQKRHFFPSTGNPDMTTRQSRFISSFFYPIRPLVLLLLLFI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PLLNGCAGKTESDKLQVVASIEPLAWFAERIGGDRVSVSVMVPSGGNPHTYEPTPKQMAQ
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHH
VSHAALFVKAGSGVEFELDWMPRLVDLNKSMTVCNASEGVTLLPMSAEKYEHAVPAEEHH
HHHHEEEEECCCCCEEEECCCCHHHHCCCCEEEEECCCCEEEEECCHHHHHCCCCCHHCC
DHGNFDPHFWLSPANARLIAKNVERSLAAIDPAGKEYYAANAAALDRELQALDSEIRKQL
CCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVVKNRRFLVFHPAWGYFAHEYGLEQIAAEEEGKTLTPRQMERVIGEARSAGIRVVFVSP
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
QFSSAQADAIAGDIGGQTVTVDPLAHDYAANLRKATAAFVQSMQ
CCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMGKPDPLQRFGFSAVILFLQKRHFFPSTGNPDMTTRQSRFISSFFYPIRPLVLLLLLFI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PLLNGCAGKTESDKLQVVASIEPLAWFAERIGGDRVSVSVMVPSGGNPHTYEPTPKQMAQ
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHH
VSHAALFVKAGSGVEFELDWMPRLVDLNKSMTVCNASEGVTLLPMSAEKYEHAVPAEEHH
HHHHEEEEECCCCCEEEECCCCHHHHCCCCEEEEECCCCEEEEECCHHHHHCCCCCHHCC
DHGNFDPHFWLSPANARLIAKNVERSLAAIDPAGKEYYAANAAALDRELQALDSEIRKQL
CCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVVKNRRFLVFHPAWGYFAHEYGLEQIAAEEEGKTLTPRQMERVIGEARSAGIRVVFVSP
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
QFSSAQADAIAGDIGGQTVTVDPLAHDYAANLRKATAAFVQSMQ
CCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]