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The map label for this gene is 21674666

Identifier: 21674666

GI number: 21674666

Start: 1752474

End: 1753103

Strand: Direct

Name: 21674666

Synonym: CT1853

Alternate gene names: NA

Gene position: 1752474-1753103 (Clockwise)

Preceding gene: 21674661

Following gene: 21674667

Centisome position: 81.32

GC content: 59.21

Gene sequence:

>630_bases
ATGAAAAGGCTTGGCGCCGATTTTTACCAGATGCCAACAATCTTGCTTGCCGAGCGGCTACTCGGCAAGATTTTCGTCCA
TCACGAAGTATCGGGCCGGGTGACCAAAGGACGGATCGTCGAAACCGAAGCCTACCTCGGCGATGGCGACGAGGCCTGCC
ACGCATGGCGCGGCATGACAGAGCGCAATCATGTGATGTTCGGCCCACCCGGCCACCTGTACATCTACTTCTCCTACGGC
TGCCACTATCTGGCGAACATCGTCTCGGAACAGAAGGGCATAGCTGGCGCAGTCCTGCTCCGGGCTATGGAACCAATCGA
AGGCATCGAATGGATGCAGGAACGGCGCGGAACGACTGATGAGCGCGCCCTGATGAGCGGCCCCGGCAAGCTCACCCAGG
CGCTCGGCCTCGGCCCGGCGCATTATGGCGAGAGCCTGCTCGGCGACATCTGCTGGCTCGAAGAGGCTCCGGACATACCG
CCGGAGCTGATCGGCACAAGCCCGCGCATCGGCATTTCGCGCAGTACTGATCTCCTGTGGAGAAAGTTCATCGCCGGTTC
GCCGTATATTTCGAAAACACAACCCGGCCCGCCGCCAAAAAAGAGGAAAAAAGGGTTGGAAAGTAGTTAA

Upstream 100 bases:

>100_bases
GCCAGCGAAATGAAAAATATTCAAGCGGTTAATCTTCTTCAGCGACACGTTGTATTAGTATAATACTTGCATAAACTTTT
GCAAACAGGAATATCGACCC

Downstream 100 bases:

>100_bases
ATTTTCCTTTTTTAGGCTCATACGGTTACACGAGGGAACATCCATCAAGTCAACCTCAAGCCAGCCATGATCGGCACTCC
TATCCTTCCAGAAATTCGTG

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMTERNHVMFGPPGHLYIYFSYG
CHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTDERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIP
PELIGTSPRIGISRSTDLLWRKFIAGSPYISKTQPGPPPKKRKKGLESS

Sequences:

>Translated_209_residues
MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMTERNHVMFGPPGHLYIYFSYG
CHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTDERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIP
PELIGTSPRIGISRSTDLLWRKFIAGSPYISKTQPGPPPKKRKKGLESS
>Mature_209_residues
MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMTERNHVMFGPPGHLYIYFSYG
CHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTDERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIP
PELIGTSPRIGISRSTDLLWRKFIAGSPYISKTQPGPPPKKRKKGLESS

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI62632765, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI62632771, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_CHLTE (Q8KBD5)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662731.1
- ProteinModelPortal:   Q8KBD5
- SMR:   Q8KBD5
- GeneID:   1007834
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1853
- NMPDR:   fig|194439.1.peg.1825
- TIGR:   CT1853
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   CLSK637971
- BioCyc:   CTEP194439:CT_1853-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 23160; Mature: 23160

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEHHHCCCCHHHHHHHCCCC
ERNHVMFGPPGHLYIYFSYGCHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTD
CCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHCCCCH
ERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIPPELIGTSPRIGISRSTDLLW
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHH
RKFIAGSPYISKTQPGPPPKKRKKGLESS
HHHHCCCCCCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEHHHCCCCHHHHHHHCCCC
ERNHVMFGPPGHLYIYFSYGCHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTD
CCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHCCCCH
ERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIPPELIGTSPRIGISRSTDLLW
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHH
RKFIAGSPYISKTQPGPPPKKRKKGLESS
HHHHCCCCCCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901