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The map label for this gene is menH [H]

Identifier: 21674658

GI number: 21674658

Start: 1745083

End: 1745910

Strand: Direct

Name: menH [H]

Synonym: CT1845

Alternate gene names: 21674658

Gene position: 1745083-1745910 (Clockwise)

Preceding gene: 21674657

Following gene: 21674659

Centisome position: 80.98

GC content: 58.82

Gene sequence:

>828_bases
ATGACCACCATTTCCCTCCACCTCACCACCGTCGGCGACCCGGCGCTACCGAAAATCGTGTTTCTGCACGGCTTCCTCGG
CTCAGGAAGCGACTGGCTTTCATTTGCCCGAAAGCTTGAGAATCGCTTTTGCAGCATCCTCGTCGATCTGCCGGGTCATG
GTGAGGCGGGAATTCCGGCGGATGGCGATCCGAAGCTGTTTTTCATGCAGACAGTCGAAGCGCTGAAGAGCAATATCCGG
CGTTTGCGCGCGGAGCCGTGCGTGCTGGTGGGCTATTCGATGGGCGGCCGGATCGGACTGGCGCTGGCGTTGCTCTATCC
GGAGCTGTTCTCGAAGGCGATAATCGTGTCGTCGTCGCCTGGACTACAGACGGACGAAAAGCGAGCATCGCGCCGAAAAA
GCGACGAGGGAATCGCCCGCAAGATCGAGCGGAATTTCGAGGGGTTCATCGGGTTCTGGTACGACCAGCCGCTTTTTTCG
ACGCTGAAAAGCCACTCGCTGTTCCGCGAGGTCGAGGCGCAACGCAAGCAGGGTACACCGCAAAATCTCGCCCGCGCGCT
GCGCCTGCTCGGCACGGGCAATCAGCCATCGTTCTGGGACAAACTCCCCGGCAACCGCCTGCCGATGCTTTTCTGCGTCG
GCGAAAAGGATGCAAAGTACGTGGATATCGCAAAGCAGGTGGTTGAACTTTGCCCATCCTCAAGCCTCGAACTCTTCGAA
CACTGCGGCCACACGCTGCACATCGAAGAGCCGGAGCGTTTTCTTGCGAGCGTGGAGCGGTTTATCGAAACGCATCCCCA
CAACAGCATTTCCCACGATGACCTGTAA

Upstream 100 bases:

>100_bases
TGCCCATGAGACTGTGCAGTTTCCGGGTTCAAAAAAAACAGCTCTTTGTGGCGTTGTCATATATTAGCAAAAAAGCGAAC
GGCCTGAAATCACCACAGCA

Downstream 100 bases:

>100_bases
GTCCCATTCCGCCGTCACGCCTCTCTAATCAACGGGGATTGTTTATATTTCAGCTCTTTTGCCTGTAGAGCCGGGGCAAC
GCCGATTTTCATCAACTACC

Product: thioesterase, menaquinone synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTTISLHLTTVGDPALPKIVFLHGFLGSGSDWLSFARKLENRFCSILVDLPGHGEAGIPADGDPKLFFMQTVEALKSNIR
RLRAEPCVLVGYSMGGRIGLALALLYPELFSKAIIVSSSPGLQTDEKRASRRKSDEGIARKIERNFEGFIGFWYDQPLFS
TLKSHSLFREVEAQRKQGTPQNLARALRLLGTGNQPSFWDKLPGNRLPMLFCVGEKDAKYVDIAKQVVELCPSSSLELFE
HCGHTLHIEEPERFLASVERFIETHPHNSISHDDL

Sequences:

>Translated_275_residues
MTTISLHLTTVGDPALPKIVFLHGFLGSGSDWLSFARKLENRFCSILVDLPGHGEAGIPADGDPKLFFMQTVEALKSNIR
RLRAEPCVLVGYSMGGRIGLALALLYPELFSKAIIVSSSPGLQTDEKRASRRKSDEGIARKIERNFEGFIGFWYDQPLFS
TLKSHSLFREVEAQRKQGTPQNLARALRLLGTGNQPSFWDKLPGNRLPMLFCVGEKDAKYVDIAKQVVELCPSSSLELFE
HCGHTLHIEEPERFLASVERFIETHPHNSISHDDL
>Mature_274_residues
TTISLHLTTVGDPALPKIVFLHGFLGSGSDWLSFARKLENRFCSILVDLPGHGEAGIPADGDPKLFFMQTVEALKSNIRR
LRAEPCVLVGYSMGGRIGLALALLYPELFSKAIIVSSSPGLQTDEKRASRRKSDEGIARKIERNFEGFIGFWYDQPLFST
LKSHSLFREVEAQRKQGTPQNLARALRLLGTGNQPSFWDKLPGNRLPMLFCVGEKDAKYVDIAKQVVELCPSSSLELFEH
CGHTLHIEEPERFLASVERFIETHPHNSISHDDL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI23200008, Length=272, Percent_Identity=26.1029411764706, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23200012, Length=272, Percent_Identity=26.1029411764706, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788598, Length=253, Percent_Identity=29.6442687747036, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30731; Mature: 30599

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTISLHLTTVGDPALPKIVFLHGFLGSGSDWLSFARKLENRFCSILVDLPGHGEAGIPA
CCEEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
DGDPKLFFMQTVEALKSNIRRLRAEPCVLVGYSMGGRIGLALALLYPELFSKAIIVSSSP
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCEEEEECCC
GLQTDEKRASRRKSDEGIARKIERNFEGFIGFWYDQPLFSTLKSHSLFREVEAQRKQGTP
CCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
QNLARALRLLGTGNQPSFWDKLPGNRLPMLFCVGEKDAKYVDIAKQVVELCPSSSLELFE
HHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHH
HCGHTLHIEEPERFLASVERFIETHPHNSISHDDL
HCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTISLHLTTVGDPALPKIVFLHGFLGSGSDWLSFARKLENRFCSILVDLPGHGEAGIPA
CEEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
DGDPKLFFMQTVEALKSNIRRLRAEPCVLVGYSMGGRIGLALALLYPELFSKAIIVSSSP
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCEEEEECCC
GLQTDEKRASRRKSDEGIARKIERNFEGFIGFWYDQPLFSTLKSHSLFREVEAQRKQGTP
CCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
QNLARALRLLGTGNQPSFWDKLPGNRLPMLFCVGEKDAKYVDIAKQVVELCPSSSLELFE
HHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHH
HCGHTLHIEEPERFLASVERFIETHPHNSISHDDL
HCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566759; 9387221; 9384377 [H]