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The map label for this gene is dnaX [H]

Identifier: 21674424

GI number: 21674424

Start: 1513030

End: 1514202

Strand: Direct

Name: dnaX [H]

Synonym: CT1606

Alternate gene names: 21674424

Gene position: 1513030-1514202 (Clockwise)

Preceding gene: 21674423

Following gene: 21674427

Centisome position: 70.21

GC content: 60.61

Gene sequence:

>1173_bases
ATGAGCTGGAATTCGATTGTCGGTCACGAACCACAACTCCGGGTGCTGAAAACAGCGCTCGGAGCCAACCGTTTGGCTCA
TGCCTATCTCTTTACCGGTCCCGAGGGCTCAGGCAAGGAGAGCGTGGCGTTTGAACTCGCCAAAATTCTCAACTGCCGGA
GCTCCGGCAACCTTTCGGGCGAAGGCTCGTGCGGCGAATGCGAAAGCTGCCGCCAGACCGACCTGCTCATGCACCCCAAC
ATCGAGTACCTCTTCCCCGTCGAAGCAGCCCTGCTCGAAACCATCGATCCGTCGAAAAAAGAGAACAAGAAGCTCACCGA
AGCTCGGGAGCGCTACGAGGCGCTGCTCGACGAAAAGCGAAAAAATCCATTCTTCACGCCCGCTATGGAGCGTTCGATGG
GCATCCTGACCGAGCAGGTGGTGATGTTGCAACAGAAGGCCTCGCTCGCCCCGCGCGACGGCGGCAAAAAGGTGTTCATC
ATCTCACAGGCCGAGCGACTCCACCCGACCGCGGCCAACAAGCTCCTCAAGCTGCTCGAAGAGCCACCGGCGCACGTCGT
GTTCATTCTCGTCTCGTCGCGGCCCGAATCGGTGCTGCCAACGATCCGCTCGCGCTGTCAGCTCCTGAACTTCGCCCGCC
CGCGCCCGGCGGAGATCGAGGCGTGGATCGCCCGACGCGCTCCGCAGCTGGACAAAACCGAACGCCACTTCATCGTGAGC
CTCTCACGCGGCAACCTTTGCAGCGCGCTTGAACTGATCGAAGCCGAAACCGGCGAAGGAGCTGCCCCGGCGGTGGTCGG
CATCCGCAACAAAGCCATCGACTACCTCCGCAACATCCTCGTGCCTGCGAAGTTCCACGAAGCCATCGGCACGTGCGAAG
AGCTGGCCAAAAGCTCCACGCGCACAGAACAGCTCATCTTCCTCGACGCCTTGCTGCTCTTCTTCCAGGACGTCACCCGC
CGAAGCATCGACCACGCCTTTCCGGAGCTCAACAACCCCGACATCGCGGCAAACACCGACCGCTTCGTCAAAGCCTTCCC
AAACCGCGACCTCTACCGTGCCTCAACGGCCATCGAAGAAGCCATGCGCTCCATCAACCGCAACGCCAGCGTGCTCTTGG
TGATGGCCGGTTTAACGGCGGAGTTAAGAGGAATTTTGCAGGGGAAAAGGTAA

Upstream 100 bases:

>100_bases
CGCGGCCCGGTCACCGAAGCCTTGCAGCACGAGTACCTCAAAATCGTCCATTCCGGAGAAGACCCATACAACTGGCTGAC
CTTTATTTGAGCGGAGGGGC

Downstream 100 bases:

>100_bases
GAGAATAGGACTGAAAGGACGGAAGGAACAGCAAGGCATAATAGAGCTGACACTCAGAAACATCATCTTTACTTCTTCCT
ATCAAACCCATACGTCCCAT

Product: DNA polymerase III, delta subunit, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSWNSIVGHEPQLRVLKTALGANRLAHAYLFTGPEGSGKESVAFELAKILNCRSSGNLSGEGSCGECESCRQTDLLMHPN
IEYLFPVEAALLETIDPSKKENKKLTEARERYEALLDEKRKNPFFTPAMERSMGILTEQVVMLQQKASLAPRDGGKKVFI
ISQAERLHPTAANKLLKLLEEPPAHVVFILVSSRPESVLPTIRSRCQLLNFARPRPAEIEAWIARRAPQLDKTERHFIVS
LSRGNLCSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTR
RSIDHAFPELNNPDIAANTDRFVKAFPNRDLYRASTAIEEAMRSINRNASVLLVMAGLTAELRGILQGKR

Sequences:

>Translated_390_residues
MSWNSIVGHEPQLRVLKTALGANRLAHAYLFTGPEGSGKESVAFELAKILNCRSSGNLSGEGSCGECESCRQTDLLMHPN
IEYLFPVEAALLETIDPSKKENKKLTEARERYEALLDEKRKNPFFTPAMERSMGILTEQVVMLQQKASLAPRDGGKKVFI
ISQAERLHPTAANKLLKLLEEPPAHVVFILVSSRPESVLPTIRSRCQLLNFARPRPAEIEAWIARRAPQLDKTERHFIVS
LSRGNLCSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTR
RSIDHAFPELNNPDIAANTDRFVKAFPNRDLYRASTAIEEAMRSINRNASVLLVMAGLTAELRGILQGKR
>Mature_389_residues
SWNSIVGHEPQLRVLKTALGANRLAHAYLFTGPEGSGKESVAFELAKILNCRSSGNLSGEGSCGECESCRQTDLLMHPNI
EYLFPVEAALLETIDPSKKENKKLTEARERYEALLDEKRKNPFFTPAMERSMGILTEQVVMLQQKASLAPRDGGKKVFII
SQAERLHPTAANKLLKLLEEPPAHVVFILVSSRPESVLPTIRSRCQLLNFARPRPAEIEAWIARRAPQLDKTERHFIVSL
SRGNLCSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTRR
SIDHAFPELNNPDIAANTDRFVKAFPNRDLYRASTAIEEAMRSINRNASVLLVMAGLTAELRGILQGKR

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787341, Length=225, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43365; Mature: 43233

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNSIVGHEPQLRVLKTALGANRLAHAYLFTGPEGSGKESVAFELAKILNCRSSGNLSG
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
EGSCGECESCRQTDLLMHPNIEYLFPVEAALLETIDPSKKENKKLTEARERYEALLDEKR
CCCCCCCHHHHCCCEEECCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
KNPFFTPAMERSMGILTEQVVMLQQKASLAPRDGGKKVFIISQAERLHPTAANKLLKLLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHH
EPPAHVVFILVSSRPESVLPTIRSRCQLLNFARPRPAEIEAWIARRAPQLDKTERHFIVS
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
LSRGNLCSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSST
ECCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
RTEQLIFLDALLLFFQDVTRRSIDHAFPELNNPDIAANTDRFVKAFPNRDLYRASTAIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHH
AMRSINRNASVLLVMAGLTAELRGILQGKR
HHHHHCCCCEEEEEECCHHHHHHHHHCCCC
>Mature Secondary Structure 
SWNSIVGHEPQLRVLKTALGANRLAHAYLFTGPEGSGKESVAFELAKILNCRSSGNLSG
CCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
EGSCGECESCRQTDLLMHPNIEYLFPVEAALLETIDPSKKENKKLTEARERYEALLDEKR
CCCCCCCHHHHCCCEEECCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
KNPFFTPAMERSMGILTEQVVMLQQKASLAPRDGGKKVFIISQAERLHPTAANKLLKLLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHH
EPPAHVVFILVSSRPESVLPTIRSRCQLLNFARPRPAEIEAWIARRAPQLDKTERHFIVS
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
LSRGNLCSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSST
ECCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
RTEQLIFLDALLLFFQDVTRRSIDHAFPELNNPDIAANTDRFVKAFPNRDLYRASTAIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHH
AMRSINRNASVLLVMAGLTAELRGILQGKR
HHHHHCCCCEEEEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]