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The map label for this gene is trpD

Identifier: 21674427

GI number: 21674427

Start: 1515934

End: 1516989

Strand: Direct

Name: trpD

Synonym: CT1609

Alternate gene names: 21674427

Gene position: 1515934-1516989 (Clockwise)

Preceding gene: 21674424

Following gene: 21674428

Centisome position: 70.35

GC content: 60.04

Gene sequence:

>1056_bases
ATGCGTCAACAGGAGATTCTTCAGAAGCTGCTGGAGGGCCACGACCTTTCCCGGCAGGAGATGGAAACGTGCATGAACTC
AATCATGGAAAACCGGTTCACCGATGCCGGCACCGGAGCCATACTGGCGCTGTTGCAGAAAAAGGGAGCCACTCCCGCCG
AGGTAATCGGGGCCTGTGCAAGCATCGTATCGAAATCCACACCGGTCACGCTCGACCAGCAGGCTGTCGATACCTGCGGC
ACGGGCGGCGATCACACGGGCACCTTCAATATTTCGACCGCCGCAGCCTTTATCGCCTGCGGCGCGGGTATTCCTATTGC
CAAACACGGCAACCGCTCGATCACCAGCAAGTGCGGCAGTGCCGATGTGCTCGAAGCACTCGGCTACCAGGTCGATCTGC
CGCCCTGCGCCACCGAGGAGCTGTTCCGCGAAACCGGCTTCGCCTTCCTCTTCGCCCCGCTTTACCATCCTTCAATGAAG
GCCGTGGCGGCCATCCGCAAGGAGCTTGGCATCAAGACAATCTTCAACATGCTCGGCCCGATCATCAATCCGGCAGGGGT
GCGGCGGCAACTCATTGGGGTGTTCGACCCTTCGGTGATGGATATTTACGCCGAGGTGCTCCTGCTCAACGGTTGCGAAC
ACGCCATGCTCGTCCACGGCAGCACGGGCAACAGCATGGGCCTCGACGAACCGAGCGTCTGCGGGCCAACCTCGATGATC
GAGCTGCATCAGGGACAGATTATCCGCCACACCGTCGAGCCGGAAGATTTCGGCCTCGGCAGGTGGGATATCGGCGAGCT
CGCCGGAGGCGACAGCCACGTCAACGCGCAGATCATCCGCGAGATCCTCGACGGTTCGGCACCGCAGGCCAAAATCGACG
CCGCACTGTTCGCCTCGGCCATCACCTGCTACGTTTCGGGCAAAGCCTCCTGCATCGACGAGGGCATGAGCCTGTCCAAA
GGAAGCCTCGAAACCTGTGAAGCGCTGGACAAGATGAACCTGATTATTAAAACGAACCAGCGGCTTGCGCAGAAATGCGC
TTCGGCAACAAACTAA

Upstream 100 bases:

>100_bases
TCTGCTTTGTGCAAAAGGGCTTTTGTTGCTAAAGGGGCCGACAGTTAGTATAATGTAAGCGAATAATTTCTTCATTTCGA
CCCCGCTTTGCATCACTACT

Downstream 100 bases:

>100_bases
CGGGTTTCTGAATACCCTTACAATTTGCTGGAAAACATGTATTATATTTGCTGTCTGTTTCCAGCCGAAGTAAGAATCTG
TACATCATGAACGGAAGCGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACASIVSKSTPVTLDQQAVDTCG
TGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGSADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMK
AVAAIRKELGIKTIFNMLGPIINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMI
ELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASAITCYVSGKASCIDEGMSLSK
GSLETCEALDKMNLIIKTNQRLAQKCASATN

Sequences:

>Translated_351_residues
MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACASIVSKSTPVTLDQQAVDTCG
TGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGSADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMK
AVAAIRKELGIKTIFNMLGPIINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMI
ELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASAITCYVSGKASCIDEGMSLSK
GSLETCEALDKMNLIIKTNQRLAQKCASATN
>Mature_351_residues
MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACASIVSKSTPVTLDQQAVDTCG
TGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGSADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMK
AVAAIRKELGIKTIFNMLGPIINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMI
ELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASAITCYVSGKASCIDEGMSLSK
GSLETCEALDKMNLIIKTNQRLAQKCASATN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=37.8091872791519, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320561, Length=283, Percent_Identity=31.4487632508834, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CHLTE (Q8KC17)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662492.1
- ProteinModelPortal:   Q8KC17
- SMR:   Q8KC17
- GeneID:   1006106
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1609
- NMPDR:   fig|194439.1.peg.1586
- TIGR:   CT1609
- HOGENOM:   HBG559996
- OMA:   ERTHEES
- ProtClustDB:   PRK00188
- BioCyc:   CTEP194439:CT_1609-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37211; Mature: 37211

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SIVSKSTPVTLDQQAVDTCGTGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGS
HHHCCCCCCEECHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCC
ADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMKAVAAIRKELGIKTIFNMLGP
HHHHHHCCCEECCCCCCHHHHHHHCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMI
HCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHH
ELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASA
HHHCCCEEEEECCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ITCYVSGKASCIDEGMSLSKGSLETCEALDKMNLIIKTNQRLAQKCASATN
HHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHCCCC
>Mature Secondary Structure
MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SIVSKSTPVTLDQQAVDTCGTGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGS
HHHCCCCCCEECHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCC
ADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMKAVAAIRKELGIKTIFNMLGP
HHHHHHCCCEECCCCCCHHHHHHHCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMI
HCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHH
ELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASA
HHHCCCEEEEECCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ITCYVSGKASCIDEGMSLSKGSLETCEALDKMNLIIKTNQRLAQKCASATN
HHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901