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The map label for this gene is ntrC [H]

Identifier: 21674317

GI number: 21674317

Start: 1401052

End: 1402182

Strand: Direct

Name: ntrC [H]

Synonym: CT1497

Alternate gene names: 21674317

Gene position: 1401052-1402182 (Clockwise)

Preceding gene: 21674316

Following gene: 21674319

Centisome position: 65.02

GC content: 58.89

Gene sequence:

>1131_bases
ATGAGCCGCAGCATCGAATTCATCGGACGCTCGGCGGGCATCGTCCAGCTCAGGGAGCTGGCCATGCAGGTCGCCGATAC
TGACGTCACGGTGCTCATCACCGGTGAAACCGGTTCCGGAAAGGAGGTTCTCGCCCGCTTCATCCACGACCACAGCCGCC
GGGCGGGCAAAAGCATGATTCCGGTCAACTGCGGAGCAATCCCGTCGGGCATTCTCGAATCTGAGCTGTTCGGCCATGAA
AAGGGGGCTTTCACCGGTGCGGTACAGGCAAGAAAGGGATACTTCGAGAGCGCTGACAAAGGCACGATTTTTCTGGATGA
AATCGGCGAAATGCCGCTCGAAACGCAGGTCAAGTTCCTGCGCGTCATCGAAACCGGCCAGTTCCAGCGGGTCGGTGCAT
CGGAAACAATCTCCGCGGACACGAGGATCATCGCGGCCACCAACCGCAACCTCAACCAAGCGGTTGCCGAAAAGCACTTC
AGGGAGGATCTTTACTATCGGCTCAAAAGCGTGGAGTTGCTCATTCCGCCGCTGAGAGAACGGGGCAGCGACATCCTCAT
GCTGGCCGAGCACTTCGTGCACGAGTTCGAGCGCAAGCACGCCATCGCATTCGAGGGATTCAGTCAGGAGTCGGGCGAGC
TGATGCTGCGCTACCCGTGGCCGGGCAACGTGCGGGAGTTGCGCAACCTGATCGAAGCGCTGCTCATCCTCGAACGGGGC
AAAAAGATCACACCCGATATTCTTGAAAAACATCTGGTGCAGCGCAGCCGTCACAAAGGGCTGGTGCATGAACCCGGCAA
ATCGGAGAAAAACGAATTGCATCTGATCTACAGTAGCCTCATCCAGCTTCGGCAGGAGATCGATGAAATCCGGCAGATGC
TGCAACAGGCACTCCTCTACCGCCAGCCCACCTCGCCACTGCTGCTGCCAGCATTGCCTGCACCGCCCGCCGCGCAGGAC
TCGACGCTCCCGTCTGGTGGCAATGAAGCGCCCGTGCCGCTCAAAGAGCTGGAAAAGCGCGCCATCGGCGAGGCTCTGAC
AAAATTCGACGGTAACAAACGAAAAACCGCCCTGGCCCTCGGCATCAATGAGCGGACGCTCTACCGCAAAATCAAGGAGT
ACGGACTGTAG

Upstream 100 bases:

>100_bases
TTCACGACCCAGCAGGAGGCAGCAGCTTTCGCGCGTACGCTTCCGATCGAATCAATCGTCGTACCACCGCAACCATGACC
ATGATACCGATCAAGCAACC

Downstream 100 bases:

>100_bases
GAAGAATTACATATTGTTGCTCACAACACGTTTTCGTTTTTCGCCTACTACCGCTTTCTCACCGCCGCCACCAGCGCCAG
CACACCTGCAATCCCCAGAC

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSRSIEFIGRSAGIVQLRELAMQVADTDVTVLITGETGSGKEVLARFIHDHSRRAGKSMIPVNCGAIPSGILESELFGHE
KGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKFLRVIETGQFQRVGASETISADTRIIAATNRNLNQAVAEKHF
REDLYYRLKSVELLIPPLRERGSDILMLAEHFVHEFERKHAIAFEGFSQESGELMLRYPWPGNVRELRNLIEALLILERG
KKITPDILEKHLVQRSRHKGLVHEPGKSEKNELHLIYSSLIQLRQEIDEIRQMLQQALLYRQPTSPLLLPALPAPPAAQD
STLPSGGNEAPVPLKELEKRAIGEALTKFDGNKRKTALALGINERTLYRKIKEYGL

Sequences:

>Translated_376_residues
MSRSIEFIGRSAGIVQLRELAMQVADTDVTVLITGETGSGKEVLARFIHDHSRRAGKSMIPVNCGAIPSGILESELFGHE
KGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKFLRVIETGQFQRVGASETISADTRIIAATNRNLNQAVAEKHF
REDLYYRLKSVELLIPPLRERGSDILMLAEHFVHEFERKHAIAFEGFSQESGELMLRYPWPGNVRELRNLIEALLILERG
KKITPDILEKHLVQRSRHKGLVHEPGKSEKNELHLIYSSLIQLRQEIDEIRQMLQQALLYRQPTSPLLLPALPAPPAAQD
STLPSGGNEAPVPLKELEKRAIGEALTKFDGNKRKTALALGINERTLYRKIKEYGL
>Mature_375_residues
SRSIEFIGRSAGIVQLRELAMQVADTDVTVLITGETGSGKEVLARFIHDHSRRAGKSMIPVNCGAIPSGILESELFGHEK
GAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKFLRVIETGQFQRVGASETISADTRIIAATNRNLNQAVAEKHFR
EDLYYRLKSVELLIPPLRERGSDILMLAEHFVHEFERKHAIAFEGFSQESGELMLRYPWPGNVRELRNLIEALLILERGK
KITPDILEKHLVQRSRHKGLVHEPGKSEKNELHLIYSSLIQLRQEIDEIRQMLQQALLYRQPTSPLLLPALPAPPAAQDS
TLPSGGNEAPVPLKELEKRAIGEALTKFDGNKRKTALALGINERTLYRKIKEYGL

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=370, Percent_Identity=38.3783783783784, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789087, Length=246, Percent_Identity=48.3739837398374, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI87082117, Length=239, Percent_Identity=48.9539748953975, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1789233, Length=373, Percent_Identity=38.0697050938338, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1788905, Length=246, Percent_Identity=45.9349593495935, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1790299, Length=374, Percent_Identity=38.2352941176471, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1790437, Length=238, Percent_Identity=46.218487394958, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI87082152, Length=246, Percent_Identity=44.3089430894309, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786524, Length=276, Percent_Identity=42.0289855072464, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87081872, Length=227, Percent_Identity=44.0528634361233, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=244, Percent_Identity=40.5737704918033, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789828, Length=258, Percent_Identity=34.4961240310078, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081858, Length=230, Percent_Identity=32.1739130434783, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 42157; Mature: 42026

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSIEFIGRSAGIVQLRELAMQVADTDVTVLITGETGSGKEVLARFIHDHSRRAGKSMI
CCCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PVNCGAIPSGILESELFGHEKGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKFL
CEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHCCCCHHHHHHHH
RVIETGQFQRVGASETISADTRIIAATNRNLNQAVAEKHFREDLYYRLKSVELLIPPLRE
HHHHCCCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RGSDILMLAEHFVHEFERKHAIAFEGFSQESGELMLRYPWPGNVRELRNLIEALLILERG
CCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KKITPDILEKHLVQRSRHKGLVHEPGKSEKNELHLIYSSLIQLRQEIDEIRQMLQQALLY
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQPTSPLLLPALPAPPAAQDSTLPSGGNEAPVPLKELEKRAIGEALTKFDGNKRKTALAL
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
GINERTLYRKIKEYGL
CCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SRSIEFIGRSAGIVQLRELAMQVADTDVTVLITGETGSGKEVLARFIHDHSRRAGKSMI
CCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PVNCGAIPSGILESELFGHEKGAFTGAVQARKGYFESADKGTIFLDEIGEMPLETQVKFL
CEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHCCCCHHHHHHHH
RVIETGQFQRVGASETISADTRIIAATNRNLNQAVAEKHFREDLYYRLKSVELLIPPLRE
HHHHCCCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RGSDILMLAEHFVHEFERKHAIAFEGFSQESGELMLRYPWPGNVRELRNLIEALLILERG
CCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KKITPDILEKHLVQRSRHKGLVHEPGKSEKNELHLIYSSLIQLRQEIDEIRQMLQQALLY
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQPTSPLLLPALPAPPAAQDSTLPSGGNEAPVPLKELEKRAIGEALTKFDGNKRKTALAL
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
GINERTLYRKIKEYGL
CCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]