Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 21674217

GI number: 21674217

Start: 1307458

End: 1309884

Strand: Reverse

Name: zraS [C]

Synonym: CT1396

Alternate gene names: 21674217

Gene position: 1309884-1307458 (Counterclockwise)

Preceding gene: 21674220

Following gene: 21674215

Centisome position: 60.79

GC content: 49.98

Gene sequence:

>2427_bases
ATGTTCGGATTTTCGAATTCGGATATATCCGTTTCTTCTGGACATACTTCCCATCTGGATGAGGTGTTGCCTCAGTCCAT
GTACATGGTGGATGCGGATGGACGCATGGTACGCTGGAGCCCGTGGTTTCGGGACCGGATCGCCGGATTTTCTGACGCGG
AGATGGCTTCGACCGATTTTCTTGAGCTGATCCATCCCGAAGACAGAGCGTTGGTTCGGCAGCGAATGCGGAAGATTCTC
GATCAGGGCGTTCAGGACAGTCTTGAGGTCAGGATATTTCTCAAAGGTGGGCCTGCATTTCGCTGGTTTCTTCTTATGGC
CAACCGATATGAATATGCCGGGCACTATTTCATAACCGGAACAGGCATTGATATTACCCGTCTGAAAAATGCGGGTATGG
CTATGACGCTTGGTGAACAGCGGTACCGTTCAATGTTTGAACAGGCTGATGTTCCGGTGTTCATTACCGATACTGACGGT
GCCCTTGTATATGTTTCTCCGGCTTTTGAAAAGATAACCGGTTACTCTTTTTCGGAATGCGAAGGTAGGCCATTCACCGA
ATGTTGCAAAGAAATTGAGCCGGGAGGCGCATCTCTTTCCATGTTTAGCGATGTCATTTCAAACGATTTTAACTGCAGGG
CCGGCGAAATCACGATTCTCAAGAAAGATGGCTCGTCGTGTTACGTTGAATTGAAATTTCAGCGTTATCATGACAACCGT
ACCGCAGGTGCGATCGGGGTGCTTTGCGATCTCTCCCAGCGCAAAAGGTTTGAATTGCTGACGGAGTTCCGTCTCGAGCT
TTTGCAGTATGCCGACAAGATGTCTATCGATGAAATTATGCAAAAGATGCTCGACAAAGCTGAAAAGCTTACGGACAGCC
TGGCCAGCTTTATCTGTTTTCTTTCTCATGAGTCGGGTGGCGTGTCTGACTGTATTTTATCGAGCAGTTTTCGTGACCGG
ATGGGGGCGACGAGCCGAAGCGGGGAGCAGCTTCCCTTCGATGTGATGCCGTTTCTTAATGATGCCGTCAAATCCGGTCG
TGCCAGTATTGTCAACGGATACCCTGAACAGGGGCATTCTGACGTTTCTTTTGATCATCCAGCCATATTCAGCAGTCTTG
CAGTCCCGATCATCGAGCGCGGCAATGTTGTTGCCGTTCTGCTGGTTAGCAACAAGCGTACGCCCTATACCGACAATGAT
GCTCACTGGGTAGGTACGCTTACTGATCTTGTCTGGGAGATTGTGCTCCAGAAACGGGCCGCGCAGGCCGAGATTAACCA
TCAGTCGGTTCTGCTGCAAATTCAGAAGATGGAGCTTGTTGGTCAGCTTGCTGGTGGTATAGCTCATGATTTCAACAACA
TGCTTGGGGTTATTCTCGGCAATGCCGAACTGGCACTGTCGAGTGATGACCTTGAGGCATCGGTTGAGGAGAATCTGCAG
GAGATTTACCGGGCGGCTGAACGTTCGGCTGAAATGATCAGCCAGTTGCTTGCATTCGCTCGAAAGCAGACGGCTATGCC
CAAACTGGTGCATATCAATGAGGTAGTTCAGGATTCGCTGCCGATTCTGCAAAGAGTAGCGGGAGAAAAAATTGAGATTG
AATTACGGCCATGTGGTGATGACTGCCGGCTTCACATCGATCCGTCCCAGATCGATCAGATTTTGATGAATCTCTGCCTT
AATGCCCGTGATGCTATGAATGGTACCGGAAAAATCGTTATTGAGGTGAAGCGAATCAACATCGCCCCGTCACAGTATAG
TAGCGGTGATTTCAGATTGCCAGGGGATTTCATCATGCTTTCCGTGACCGATACCGGTCAGGGGATTGCCGATATCCACA
AATCGCACATTTTCGAGCCGTTTTTCACCACCAAGGCGCAGGGGAAAGGTACCGGTCTCGGACTTTCGTCGGTCTATGGT
ATTGTCAAACAGAACCGGGGGTTTGTCGATTTTGAAAGTAACGTGGGAGTCGGGACTACGTTCCATATCTATCTGCCTCT
CTATAAAAAGCATGATGTTTCTGGAGCTGACAACGGCACCGTCAGCAGCAACAATGAACAGACGACGATTCTTGTTGTCG
AAGATGAACCCGAAATTCTCAATCTTTGCCAGGTCATGCTTCAAAAGTCCGGATTCAAAGTGTATGCCGCCAACTCTCCA
TCCGAAGCCATCGTGATTGCCGAAGAAAACAGCGGCAAGATCGATTTGGTTCTGACCGATGTGGTTATGCCGGGGATGAA
CGGGGTTGATCTCGCCTCAAAGCTTTTGACCATCAGTCCCGGCTTCAGGGTGCTTTTTATGTCGGGATATCCGGCGGACG
TGATTGCCAGTCACGGGGTGGATAACCCGCTGGTCAACGTCATCCGCAAGCCCTTCACGTTCAAGGCACTGGTCGAGAAA
GTTCAGGAAAGCCTCGCCGTGGAGTGA

Upstream 100 bases:

>100_bases
TGCTACTGGTGTATAGGTGAGCAATATATGAAAGGTGTATTTTGAGTCCGGCAAACCTTTAAACATTATCTTCCTCATGT
TAGAGAATAGCACAAACGCA

Downstream 100 bases:

>100_bases
ACCGCCGGAAGCAGACGTCTCCGGTGCCGTTTATGCTTTTGATGACTCAGGCAGGGTGGTAATGTCGAGTTGTAGGCGTT
TCACCGTCATGTTCCAGTGA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MFGFSNSDISVSSGHTSHLDEVLPQSMYMVDADGRMVRWSPWFRDRIAGFSDAEMASTDFLELIHPEDRALVRQRMRKIL
DQGVQDSLEVRIFLKGGPAFRWFLLMANRYEYAGHYFITGTGIDITRLKNAGMAMTLGEQRYRSMFEQADVPVFITDTDG
ALVYVSPAFEKITGYSFSECEGRPFTECCKEIEPGGASLSMFSDVISNDFNCRAGEITILKKDGSSCYVELKFQRYHDNR
TAGAIGVLCDLSQRKRFELLTEFRLELLQYADKMSIDEIMQKMLDKAEKLTDSLASFICFLSHESGGVSDCILSSSFRDR
MGATSRSGEQLPFDVMPFLNDAVKSGRASIVNGYPEQGHSDVSFDHPAIFSSLAVPIIERGNVVAVLLVSNKRTPYTDND
AHWVGTLTDLVWEIVLQKRAAQAEINHQSVLLQIQKMELVGQLAGGIAHDFNNMLGVILGNAELALSSDDLEASVEENLQ
EIYRAAERSAEMISQLLAFARKQTAMPKLVHINEVVQDSLPILQRVAGEKIEIELRPCGDDCRLHIDPSQIDQILMNLCL
NARDAMNGTGKIVIEVKRINIAPSQYSSGDFRLPGDFIMLSVTDTGQGIADIHKSHIFEPFFTTKAQGKGTGLGLSSVYG
IVKQNRGFVDFESNVGVGTTFHIYLPLYKKHDVSGADNGTVSSNNEQTTILVVEDEPEILNLCQVMLQKSGFKVYAANSP
SEAIVIAEENSGKIDLVLTDVVMPGMNGVDLASKLLTISPGFRVLFMSGYPADVIASHGVDNPLVNVIRKPFTFKALVEK
VQESLAVE

Sequences:

>Translated_808_residues
MFGFSNSDISVSSGHTSHLDEVLPQSMYMVDADGRMVRWSPWFRDRIAGFSDAEMASTDFLELIHPEDRALVRQRMRKIL
DQGVQDSLEVRIFLKGGPAFRWFLLMANRYEYAGHYFITGTGIDITRLKNAGMAMTLGEQRYRSMFEQADVPVFITDTDG
ALVYVSPAFEKITGYSFSECEGRPFTECCKEIEPGGASLSMFSDVISNDFNCRAGEITILKKDGSSCYVELKFQRYHDNR
TAGAIGVLCDLSQRKRFELLTEFRLELLQYADKMSIDEIMQKMLDKAEKLTDSLASFICFLSHESGGVSDCILSSSFRDR
MGATSRSGEQLPFDVMPFLNDAVKSGRASIVNGYPEQGHSDVSFDHPAIFSSLAVPIIERGNVVAVLLVSNKRTPYTDND
AHWVGTLTDLVWEIVLQKRAAQAEINHQSVLLQIQKMELVGQLAGGIAHDFNNMLGVILGNAELALSSDDLEASVEENLQ
EIYRAAERSAEMISQLLAFARKQTAMPKLVHINEVVQDSLPILQRVAGEKIEIELRPCGDDCRLHIDPSQIDQILMNLCL
NARDAMNGTGKIVIEVKRINIAPSQYSSGDFRLPGDFIMLSVTDTGQGIADIHKSHIFEPFFTTKAQGKGTGLGLSSVYG
IVKQNRGFVDFESNVGVGTTFHIYLPLYKKHDVSGADNGTVSSNNEQTTILVVEDEPEILNLCQVMLQKSGFKVYAANSP
SEAIVIAEENSGKIDLVLTDVVMPGMNGVDLASKLLTISPGFRVLFMSGYPADVIASHGVDNPLVNVIRKPFTFKALVEK
VQESLAVE
>Mature_808_residues
MFGFSNSDISVSSGHTSHLDEVLPQSMYMVDADGRMVRWSPWFRDRIAGFSDAEMASTDFLELIHPEDRALVRQRMRKIL
DQGVQDSLEVRIFLKGGPAFRWFLLMANRYEYAGHYFITGTGIDITRLKNAGMAMTLGEQRYRSMFEQADVPVFITDTDG
ALVYVSPAFEKITGYSFSECEGRPFTECCKEIEPGGASLSMFSDVISNDFNCRAGEITILKKDGSSCYVELKFQRYHDNR
TAGAIGVLCDLSQRKRFELLTEFRLELLQYADKMSIDEIMQKMLDKAEKLTDSLASFICFLSHESGGVSDCILSSSFRDR
MGATSRSGEQLPFDVMPFLNDAVKSGRASIVNGYPEQGHSDVSFDHPAIFSSLAVPIIERGNVVAVLLVSNKRTPYTDND
AHWVGTLTDLVWEIVLQKRAAQAEINHQSVLLQIQKMELVGQLAGGIAHDFNNMLGVILGNAELALSSDDLEASVEENLQ
EIYRAAERSAEMISQLLAFARKQTAMPKLVHINEVVQDSLPILQRVAGEKIEIELRPCGDDCRLHIDPSQIDQILMNLCL
NARDAMNGTGKIVIEVKRINIAPSQYSSGDFRLPGDFIMLSVTDTGQGIADIHKSHIFEPFFTTKAQGKGTGLGLSSVYG
IVKQNRGFVDFESNVGVGTTFHIYLPLYKKHDVSGADNGTVSSNNEQTTILVVEDEPEILNLCQVMLQKSGFKVYAANSP
SEAIVIAEENSGKIDLVLTDVVMPGMNGVDLASKLLTISPGFRVLFMSGYPADVIASHGVDNPLVNVIRKPFTFKALVEK
VQESLAVE

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=32.3404255319149, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788549, Length=268, Percent_Identity=29.8507462686567, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=407, Percent_Identity=24.3243243243243, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=336, Percent_Identity=26.7857142857143, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790300, Length=265, Percent_Identity=27.5471698113208, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=318, Percent_Identity=24.8427672955975, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=25.9541984732824, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=25, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89382; Mature: 89382

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFSNSDISVSSGHTSHLDEVLPQSMYMVDADGRMVRWSPWFRDRIAGFSDAEMASTDF
CCCCCCCCEEECCCCHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHCCHHH
LELIHPEDRALVRQRMRKILDQGVQDSLEVRIFLKGGPAFRWFLLMANRYEYAGHYFITG
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCEEECCEEEEEE
TGIDITRLKNAGMAMTLGEQRYRSMFEQADVPVFITDTDGALVYVSPAFEKITGYSFSEC
CCCEEEEECCCCEEEEECHHHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHCCCCCCCC
EGRPFTECCKEIEPGGASLSMFSDVISNDFNCRAGEITILKKDGSSCYVELKFQRYHDNR
CCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEEECCCC
TAGAIGVLCDLSQRKRFELLTEFRLELLQYADKMSIDEIMQKMLDKAEKLTDSLASFICF
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSHESGGVSDCILSSSFRDRMGATSRSGEQLPFDVMPFLNDAVKSGRASIVNGYPEQGHS
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCC
DVSFDHPAIFSSLAVPIIERGNVVAVLLVSNKRTPYTDNDAHWVGTLTDLVWEIVLQKRA
CCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQAEINHQSVLLQIQKMELVGQLAGGIAHDFNNMLGVILGNAELALSSDDLEASVEENLQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEECCCCCHHHHHHHHH
EIYRAAERSAEMISQLLAFARKQTAMPKLVHINEVVQDSLPILQRVAGEKIEIELRPCGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
DCRLHIDPSQIDQILMNLCLNARDAMNGTGKIVIEVKRINIAPSQYSSGDFRLPGDFIML
CCEEEECHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEEECCCCCCCCCEECCCCEEEE
SVTDTGQGIADIHKSHIFEPFFTTKAQGKGTGLGLSSVYGIVKQNRGFVDFESNVGVGTT
EEECCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCEE
FHIYLPLYKKHDVSGADNGTVSSNNEQTTILVVEDEPEILNLCQVMLQKSGFKVYAANSP
EEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCC
SEAIVIAEENSGKIDLVLTDVVMPGMNGVDLASKLLTISPGFRVLFMSGYPADVIASHGV
CCEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHEEECCCCEEEEECCCCHHHHHHCCC
DNPLVNVIRKPFTFKALVEKVQESLAVE
CHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGFSNSDISVSSGHTSHLDEVLPQSMYMVDADGRMVRWSPWFRDRIAGFSDAEMASTDF
CCCCCCCCEEECCCCHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHCCHHH
LELIHPEDRALVRQRMRKILDQGVQDSLEVRIFLKGGPAFRWFLLMANRYEYAGHYFITG
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCEEECCEEEEEE
TGIDITRLKNAGMAMTLGEQRYRSMFEQADVPVFITDTDGALVYVSPAFEKITGYSFSEC
CCCEEEEECCCCEEEEECHHHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHCCCCCCCC
EGRPFTECCKEIEPGGASLSMFSDVISNDFNCRAGEITILKKDGSSCYVELKFQRYHDNR
CCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEEECCCC
TAGAIGVLCDLSQRKRFELLTEFRLELLQYADKMSIDEIMQKMLDKAEKLTDSLASFICF
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSHESGGVSDCILSSSFRDRMGATSRSGEQLPFDVMPFLNDAVKSGRASIVNGYPEQGHS
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCC
DVSFDHPAIFSSLAVPIIERGNVVAVLLVSNKRTPYTDNDAHWVGTLTDLVWEIVLQKRA
CCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQAEINHQSVLLQIQKMELVGQLAGGIAHDFNNMLGVILGNAELALSSDDLEASVEENLQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEECCCCCHHHHHHHHH
EIYRAAERSAEMISQLLAFARKQTAMPKLVHINEVVQDSLPILQRVAGEKIEIELRPCGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
DCRLHIDPSQIDQILMNLCLNARDAMNGTGKIVIEVKRINIAPSQYSSGDFRLPGDFIML
CCEEEECHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEEECCCCCCCCCEECCCCEEEE
SVTDTGQGIADIHKSHIFEPFFTTKAQGKGTGLGLSSVYGIVKQNRGFVDFESNVGVGTT
EEECCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCEE
FHIYLPLYKKHDVSGADNGTVSSNNEQTTILVVEDEPEILNLCQVMLQKSGFKVYAANSP
EEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCC
SEAIVIAEENSGKIDLVLTDVVMPGMNGVDLASKLLTISPGFRVLFMSGYPADVIASHGV
CCEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHEEECCCCEEEEECCCCHHHHHHCCC
DNPLVNVIRKPFTFKALVEKVQESLAVE
CHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA