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The map label for this gene is lolC [H]

Identifier: 21673929

GI number: 21673929

Start: 1038467

End: 1039735

Strand: Reverse

Name: lolC [H]

Synonym: CT1103

Alternate gene names: 21673929

Gene position: 1039735-1038467 (Counterclockwise)

Preceding gene: 21673931

Following gene: 21673928

Centisome position: 48.25

GC content: 58.55

Gene sequence:

>1269_bases
GTGAAAGCCGAGCTCTACATTGCCAGGCGATTTGCCTTTAAGCCTCGCTCGCTGTCGAAGCCGACGTTTATCGTGCTGGC
GGCGGTGATTGGGATTGCCGTGGGGACGGCGGCGCTGATTCTGACGCTGTCGATTGTGAATGGATTTGCTTCGGTCATCG
AGGGTAAGCTCATCAGGTTCACCTCGCATCTTCAGGTACGCCAGCCCGACGAACGCCTGTTTCTTGAAACCCGCCGCGAC
CTTCAGACGCTGAAAAGCGTGCCGGGCATCGTTTCGGTTTCACCGTTTCTTGAAATGAACGTGATGCTCCGGAGCCGCGC
CGGGAAGGGCGATGCAGGCGGAGAGATCGCACCAGCAATGATTCAGGGGATCGATCCACGCGAGAGTTCACGCTTTCTGC
AGAACGGACCGGAACTGCTCGAATCGGCTCCGGCTTCTGCGGACGGCTCGCTGCCCATCCTGCTTGGCAGGACGCTCGCC
GACAAGCTCGGTGTCAAGGCGGGCGATCAACTGCTGATTGTCGGCATCGCTGGCAAAAACGGCACGTCCGGCATCACCGG
CAAGGAGAGCGTGGTCGAGTTGCTGTCGAGCCTTGATCTGCACGTGGCGCGAGTCGCGGGCATCTACGACACCGGCCTCT
CCGAAGGCTTCGACGACATCATCGTCTTCGCCGATCTCGGCAGGCTTCAACAGCTTTACCATCCCGACATGATTTCGGGC
TACGAAGCCAACGTCGGCAACTTGCGCGATCTGCAGGCGATTTCGGCGACTGTGGCATCCACACTCGGTTATCCCTTTTA
CTCCTACACGGTGTACGAGCGCTACGCAAACCTTTTTGAGTGGCTCAAACTCCAGAAAAACATCATGCCACTGCTCATCA
TCACCATCACGGTTGTGGCGGTGTTCAACATCGTTTCGACGCTGCTGGTGCTCATCATCGAAAAAACGAAGGAGATCGGC
ATGTTGACCGCGCTTGGTCTCGAACCTCGCGCCGTGAGCTTGGTGTTCATGGGACAGGCGCTCATGATTTCACTGGTCGG
CATTGGCCTGGGTAACCTGCTCGCGCTTGGCCTGTCGCTCTTCGAGCTGCGATTCCATCTCATTACGCTGCCGGAAAAGA
GCTACTTCATCCGCCACGTGCCGCTCGAAATCGACCCGCTTCAATACCTCGCCGTGTCGGGGGGCGTGGCGGTGCTGACG
CTGCTTTTCGCTTTCATTCCATCACGCGTTGCCGCTTCGCTCCAGCCCGCAACCGCACTGACCACGTGA

Upstream 100 bases:

>100_bases
TCCACACCAGATGCCCAGAAATTCTTATCTTTCCCTGCATTAGAAGGGAGGTTCGTCTTCTCCTGAACCACGATCCATCA
TCCGCGCCTTTGACTACTCA

Downstream 100 bases:

>100_bases
AAAGAAAACGATGAAAGCAGGTATCTGGATAGCCGGGCGTTACAGCTTCGCGCGCAAGCGCTTCCGGGTAATCAATATTA
TTTCGGGCATCAGTCTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKAELYIARRFAFKPRSLSKPTFIVLAAVIGIAVGTAALILTLSIVNGFASVIEGKLIRFTSHLQVRQPDERLFLETRRD
LQTLKSVPGIVSVSPFLEMNVMLRSRAGKGDAGGEIAPAMIQGIDPRESSRFLQNGPELLESAPASADGSLPILLGRTLA
DKLGVKAGDQLLIVGIAGKNGTSGITGKESVVELLSSLDLHVARVAGIYDTGLSEGFDDIIVFADLGRLQQLYHPDMISG
YEANVGNLRDLQAISATVASTLGYPFYSYTVYERYANLFEWLKLQKNIMPLLIITITVVAVFNIVSTLLVLIIEKTKEIG
MLTALGLEPRAVSLVFMGQALMISLVGIGLGNLLALGLSLFELRFHLITLPEKSYFIRHVPLEIDPLQYLAVSGGVAVLT
LLFAFIPSRVAASLQPATALTT

Sequences:

>Translated_422_residues
MKAELYIARRFAFKPRSLSKPTFIVLAAVIGIAVGTAALILTLSIVNGFASVIEGKLIRFTSHLQVRQPDERLFLETRRD
LQTLKSVPGIVSVSPFLEMNVMLRSRAGKGDAGGEIAPAMIQGIDPRESSRFLQNGPELLESAPASADGSLPILLGRTLA
DKLGVKAGDQLLIVGIAGKNGTSGITGKESVVELLSSLDLHVARVAGIYDTGLSEGFDDIIVFADLGRLQQLYHPDMISG
YEANVGNLRDLQAISATVASTLGYPFYSYTVYERYANLFEWLKLQKNIMPLLIITITVVAVFNIVSTLLVLIIEKTKEIG
MLTALGLEPRAVSLVFMGQALMISLVGIGLGNLLALGLSLFELRFHLITLPEKSYFIRHVPLEIDPLQYLAVSGGVAVLT
LLFAFIPSRVAASLQPATALTT
>Mature_422_residues
MKAELYIARRFAFKPRSLSKPTFIVLAAVIGIAVGTAALILTLSIVNGFASVIEGKLIRFTSHLQVRQPDERLFLETRRD
LQTLKSVPGIVSVSPFLEMNVMLRSRAGKGDAGGEIAPAMIQGIDPRESSRFLQNGPELLESAPASADGSLPILLGRTLA
DKLGVKAGDQLLIVGIAGKNGTSGITGKESVVELLSSLDLHVARVAGIYDTGLSEGFDDIIVFADLGRLQQLYHPDMISG
YEANVGNLRDLQAISATVASTLGYPFYSYTVYERYANLFEWLKLQKNIMPLLIITITVVAVFNIVSTLLVLIIEKTKEIG
MLTALGLEPRAVSLVFMGQALMISLVGIGLGNLLALGLSLFELRFHLITLPEKSYFIRHVPLEIDPLQYLAVSGGVAVLT
LLFAFIPSRVAASLQPATALTT

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=434, Percent_Identity=25.8064516129032, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787360, Length=401, Percent_Identity=25.4364089775561, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45506; Mature: 45506

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAELYIARRFAFKPRSLSKPTFIVLAAVIGIAVGTAALILTLSIVNGFASVIEGKLIRF
CCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
TSHLQVRQPDERLFLETRRDLQTLKSVPGIVSVSPFLEMNVMLRSRAGKGDAGGEIAPAM
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCHHH
IQGIDPRESSRFLQNGPELLESAPASADGSLPILLGRTLADKLGVKAGDQLLIVGIAGKN
HCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCC
GTSGITGKESVVELLSSLDLHVARVAGIYDTGLSEGFDDIIVFADLGRLQQLYHPDMISG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCC
YEANVGNLRDLQAISATVASTLGYPFYSYTVYERYANLFEWLKLQKNIMPLLIITITVVA
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VFNIVSTLLVLIIEKTKEIGMLTALGLEPRAVSLVFMGQALMISLVGIGLGNLLALGLSL
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHH
FELRFHLITLPEKSYFIRHVPLEIDPLQYLAVSGGVAVLTLLFAFIPSRVAASLQPATAL
HHHHHHEEECCCCCEEEEECCCEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHC
TT
CC
>Mature Secondary Structure
MKAELYIARRFAFKPRSLSKPTFIVLAAVIGIAVGTAALILTLSIVNGFASVIEGKLIRF
CCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
TSHLQVRQPDERLFLETRRDLQTLKSVPGIVSVSPFLEMNVMLRSRAGKGDAGGEIAPAM
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCHHH
IQGIDPRESSRFLQNGPELLESAPASADGSLPILLGRTLADKLGVKAGDQLLIVGIAGKN
HCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCC
GTSGITGKESVVELLSSLDLHVARVAGIYDTGLSEGFDDIIVFADLGRLQQLYHPDMISG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCC
YEANVGNLRDLQAISATVASTLGYPFYSYTVYERYANLFEWLKLQKNIMPLLIITITVVA
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VFNIVSTLLVLIIEKTKEIGMLTALGLEPRAVSLVFMGQALMISLVGIGLGNLLALGLSL
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHH
FELRFHLITLPEKSYFIRHVPLEIDPLQYLAVSGGVAVLTLLFAFIPSRVAASLQPATAL
HHHHHHEEECCCCCEEEEECCCEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHC
TT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]