Click here to switch to the map view.

The map label for this gene is sucD [H]

Identifier: 21673914

GI number: 21673914

Start: 1026103

End: 1027935

Strand: Reverse

Name: sucD [H]

Synonym: CT1088

Alternate gene names: 21673914

Gene position: 1027935-1026103 (Counterclockwise)

Preceding gene: 21673915

Following gene: 21673911

Centisome position: 47.7

GC content: 57.83

Gene sequence:

>1833_bases
GTGAGCATTCTCGCAAATAAAGATACCCGGGCGGTCATCATTGGTGGTGTGGCAGGCGTCAATGCGGCAAAACGCATGGC
CCAGTTCGACTACCTGATCAACCGTCCGCTGACCGTCCAGGCTTTCGTGTATCCGCCCGAAGCGGGCCAGCAGAAAGAAA
TCTTCCGCGGTGGCGAACTCAAAAACGTTACCGTCTATCCGTCTCTGGCTCCAGCTCTCAATGAGCATCCGGACATCAAC
ACCGCCCTCATCTACCTCGGCGCATCGAGAGCGACCGAGGCCGCGATGGAAGCGCTTGAATCCCCGAACATTCAGCTGGT
CTCGATGATCACTGAAGGTGTTCCGGAAAAGGACGCCAAGCGGCTGAAAAAACTTGCCCAGAAGCTTGGCAAGATGCTGA
ACGGCCCGTCGTCGATTGGCATCATGTCTGCTGGCGAGTGCCGTCTCGGTGTGATCGGCGGCGAGTACCGCAACCTGAAA
CTCTGCAACCTCTATCGTCAGGGTTCGTTCGGTGTTCTAACCAAGTCCGGCGGTCTGTCCAACGAGGCGATGTGGCTTTG
CGCCCAGAATGGTGATGGTATCACCTCTGCCGTGGCTATTGGCGGTGACGCCTATCCGGGCACCGATTTCGTCACCTATC
TTGAAATGTTCGAGAAGGATCCTGCAACCAAGGCGGTCGTCATGATCGGCGAGGTTGGCGGTAATCTCGAAGAGGAAGCT
GCAGAGTGGCTGGCAGCCGAACCACGCCGCATCAAGCTGATCGCCGCCATTGGCGGTACCTGCCAGGAGGTTCTCCCGCA
GGGTATGAAGTTTGGTCACGCTGGCGCGAAAGAGGGCAAAAAGGGCGCTGGCTCAGCCCGCTCCAAGATGAACGCTCTGC
GTGAAGCCGGTGCGCTCGTGCCCGATACCTTTGGCGGTCTGAGCAAGGCGATCAAGCAGGTCTATGAAGAGTTGCTCGCT
TCTGGCGCCATCAAGCCGAAGCCCGAAATCGACGAGGCGCTGCTGCCTGAGCTACCGCCGAGCGTTCAGGAGGTTATGAA
GCAGGGTGAAGTGGTTGTCGAACCGCTCATCCGCACCACCATCTCCGACGATCGTGGCGAAGAGCCTCGCTATGCCGGTT
ATGCCGCTTCGGAGCTTTGCTCGAAAGGGTATGGTATCGAGGATGTCATCGGCCTGCTCTGGAGCAAGAAGCTTCCGAGC
CGCGAGGAGTCCGAGATCATCAAGCGCATCATCATGATCTCTGCTGACCACGGTCCGGCAGTGTCTGGCGCCTTTGGCAC
TATCCTCGCCGCCTGCGCAGGCATCGATATGCCGCAGGCCGTCTCTGCCGGTATGACCATGATCGGTCCGCGCTTTGGCG
GTGCTGTGACCAACGCTGGCAAATACTTCAAAATGGGTGTCAAGGAGTATCCGAACGACATTCCCGGCTTCCTTGCCTGG
ATGAAGAAAAACGTCGGCCCGGTTCCCGGCATTGGCCACAGGGTCAAGAGTCTCAGGAATCCCGACCAGCGCGTGAAGTA
CCTCGTCAGCTACGTGAAGAACGAAACCTCGCTGCACACGCCGATTCTCAACTACGCGCTCGAAGTCGAAAAGATCACGA
CCGCCAAGAAGGAGAACCTGATCCTGAACGTCGATGGCACCATAGGTTGCATCCTTATGGACCTCGGCTTCCCGGAGCAC
TCTCTGAATGGCTTCTTCGTGCTGGCCCGTACCATTGGCATGATCGGCCACTGGATCGACCAGAACAACCAGAACTCGCG
TCTGATCAGGCTCTACGATTACCTGATCAACTACGCCGTCAAACCGGAACGCCCGGTTCCCGACAAGAAGTAA

Upstream 100 bases:

>100_bases
GATGACCGATATTGTCGACCTGGCTCTGAAGTCTTGAGGGATTTCCTTGCAAGATGTTGAAATTTAAGACTATAGAAACT
CATTAAACTCTGATTGAACC

Downstream 100 bases:

>100_bases
GCGCAGAGCTTCTACAGACAACAAAAAAGCAGGTCAACTTGACCTGCTTTTTTTATGAGGGATTTGATGGTGGTGGGGAA
GTGAATTGTTATTGAAATTT

Product: citrate lyase, subunit 2

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSILANKDTRAVIIGGVAGVNAAKRMAQFDYLINRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYPSLAPALNEHPDIN
TALIYLGASRATEAAMEALESPNIQLVSMITEGVPEKDAKRLKKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEYRNLK
LCNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALREAGALVPDTFGGLSKAIKQVYEELLA
SGAIKPKPEIDEALLPELPPSVQEVMKQGEVVVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWSKKLPS
REESEIIKRIIMISADHGPAVSGAFGTILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMGVKEYPNDIPGFLAW
MKKNVGPVPGIGHRVKSLRNPDQRVKYLVSYVKNETSLHTPILNYALEVEKITTAKKENLILNVDGTIGCILMDLGFPEH
SLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPERPVPDKK

Sequences:

>Translated_610_residues
MSILANKDTRAVIIGGVAGVNAAKRMAQFDYLINRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYPSLAPALNEHPDIN
TALIYLGASRATEAAMEALESPNIQLVSMITEGVPEKDAKRLKKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEYRNLK
LCNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALREAGALVPDTFGGLSKAIKQVYEELLA
SGAIKPKPEIDEALLPELPPSVQEVMKQGEVVVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWSKKLPS
REESEIIKRIIMISADHGPAVSGAFGTILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMGVKEYPNDIPGFLAW
MKKNVGPVPGIGHRVKSLRNPDQRVKYLVSYVKNETSLHTPILNYALEVEKITTAKKENLILNVDGTIGCILMDLGFPEH
SLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPERPVPDKK
>Mature_609_residues
SILANKDTRAVIIGGVAGVNAAKRMAQFDYLINRPLTVQAFVYPPEAGQQKEIFRGGELKNVTVYPSLAPALNEHPDINT
ALIYLGASRATEAAMEALESPNIQLVSMITEGVPEKDAKRLKKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEYRNLKL
CNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEAA
EWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALREAGALVPDTFGGLSKAIKQVYEELLAS
GAIKPKPEIDEALLPELPPSVQEVMKQGEVVVEPLIRTTISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWSKKLPSR
EESEIIKRIIMISADHGPAVSGAFGTILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMGVKEYPNDIPGFLAWM
KKNVGPVPGIGHRVKSLRNPDQRVKYLVSYVKNETSLHTPILNYALEVEKITTAKKENLILNVDGTIGCILMDLGFPEHS
LNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAVKPERPVPDKK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI38569421, Length=605, Percent_Identity=35.8677685950413, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI38569423, Length=605, Percent_Identity=35.8677685950413, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI109452591, Length=216, Percent_Identity=36.1111111111111, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786949, Length=237, Percent_Identity=34.5991561181435, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557344, Length=620, Percent_Identity=38.2258064516129, Blast_Score=384, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17551266, Length=604, Percent_Identity=37.5827814569536, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17550194, Length=316, Percent_Identity=33.8607594936709, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553126, Length=316, Percent_Identity=31.0126582278481, Blast_Score=119, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324716, Length=254, Percent_Identity=31.496062992126, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363477, Length=599, Percent_Identity=36.2270450751252, Blast_Score=355, Evalue=4e-98,
Organism=Drosophila melanogaster, GI281363475, Length=599, Percent_Identity=36.2270450751252, Blast_Score=355, Evalue=5e-98,
Organism=Drosophila melanogaster, GI281363473, Length=599, Percent_Identity=36.2270450751252, Blast_Score=355, Evalue=5e-98,
Organism=Drosophila melanogaster, GI21356559, Length=235, Percent_Identity=33.1914893617021, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28574296, Length=196, Percent_Identity=37.7551020408163, Blast_Score=103, Evalue=4e-22,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 65751; Mature: 65620

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILANKDTRAVIIGGVAGVNAAKRMAQFDYLINRPLTVQAFVYPPEAGQQKEIFRGGEL
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCC
KNVTVYPSLAPALNEHPDINTALIYLGASRATEAAMEALESPNIQLVSMITEGVPEKDAK
CEEEECCCCCHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHH
RLKKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEYRNLKLCNLYRQGSFGVLTKSGGLS
HHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCC
NEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
CCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALREAGALV
HHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDTFGGLSKAIKQVYEELLASGAIKPKPEIDEALLPELPPSVQEVMKQGEVVVEPLIRTT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
ISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWSKKLPSREESEIIKRIIMISADHGPA
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCC
VSGAFGTILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMGVKEYPNDIPGFLAW
CCHHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCCCCCHHEECCHHHCCCCCHHHHHH
MKKNVGPVPGIGHRVKSLRNPDQRVKYLVSYVKNETSLHTPILNYALEVEKITTAKKENL
HHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCE
ILNVDGTIGCILMDLGFPEHSLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAV
EEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
KPERPVPDKK
CCCCCCCCCC
>Mature Secondary Structure 
SILANKDTRAVIIGGVAGVNAAKRMAQFDYLINRPLTVQAFVYPPEAGQQKEIFRGGEL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCC
KNVTVYPSLAPALNEHPDINTALIYLGASRATEAAMEALESPNIQLVSMITEGVPEKDAK
CEEEECCCCCHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHH
RLKKLAQKLGKMLNGPSSIGIMSAGECRLGVIGGEYRNLKLCNLYRQGSFGVLTKSGGLS
HHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCC
NEAMWLCAQNGDGITSAVAIGGDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEA
CCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
AEWLAAEPRRIKLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGAGSARSKMNALREAGALV
HHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDTFGGLSKAIKQVYEELLASGAIKPKPEIDEALLPELPPSVQEVMKQGEVVVEPLIRTT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
ISDDRGEEPRYAGYAASELCSKGYGIEDVIGLLWSKKLPSREESEIIKRIIMISADHGPA
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCC
VSGAFGTILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMGVKEYPNDIPGFLAW
CCHHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCCCCCCHHEECCHHHCCCCCHHHHHH
MKKNVGPVPGIGHRVKSLRNPDQRVKYLVSYVKNETSLHTPILNYALEVEKITTAKKENL
HHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHCCE
ILNVDGTIGCILMDLGFPEHSLNGFFVLARTIGMIGHWIDQNNQNSRLIRLYDYLINYAV
EEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
KPERPVPDKK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]