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The map label for this gene is sucC [H]

Identifier: 21673915

GI number: 21673915

Start: 1027999

End: 1029195

Strand: Reverse

Name: sucC [H]

Synonym: CT1089

Alternate gene names: 21673915

Gene position: 1029195-1027999 (Counterclockwise)

Preceding gene: 21673917

Following gene: 21673914

Centisome position: 47.76

GC content: 55.39

Gene sequence:

>1197_bases
ATGGCTAAAATTCTTGAAGGGCCTGCCATGAAATTGTTCAACAAGTGGGGCATTCCTGTGCCTAATTATGTTGTTATCAT
GGACCCTAAACGTCTTGCACAGCTTGGTGAAGCTAATAAATGGCTGCGTGAATCAAAACTTGTCGTCAAGGCTCACGAAG
CGATCGGCGGCCGGTTCAAGCTTGGTCTTGTCAAAATCGGACTCAATCTCGATGAGGCAATCCAGGCCTCCAGGGAGATG
CTCGGCGCCAAAGTCGGTACGGCTGAAGTCCGCCAGGTCATCGTGGCAGAAATGCTCGATCATGACGCAGAATTCTATGT
CTCCATTATCGGCAACAGAGATGGTGCCGAGTTACTGATTTCCAAATATGGCGGTGTCGATATCGAGGATAACTGGGACA
GCGTTCGCCGCATCCAGATTCCTCTCGATGAACATCCGACCATCGAGCAACTGACCGCGCTGGCCAAAGAGGCCGGTTTT
GAAGGCGAAATCGCCGAGCGCGTCGGCAAAATCTGTTCCCGCCTCGTTCTCTGCTTCGACAACGAGGACGCACAGTCTAT
CGAAATCAACCCGCTGGTCATCCGCAAGAGCGACATGCGTTTCGCTGCGCTCGACGCCGTGATGAACGTCGATTGGGACG
CCCGTTTCCGTCACGCCGACTGGGATTTCAAGCCGGTTTCTGAAATTGGCCGTCCGTTTACCGAAGCCGAGCAGCAGATC
ATGGACATCGACTCCAGGATCAAGGGTTCGGTCAAGTTCGTTGAGGTGCCTGGCGGTGAAATCGCTCTTCTGACCGCAGG
CGGAGGCGCATCGGTGTTCTATGCCGACGCAGTCGTGGCTCGCGGCGGCACCATCGCCAACTATGCAGAGTATTCGGGCG
ACCCGCCTGACTGGGCCGTGGAAGCGCTCACCGAAACCATCTGCCGTTTGCCCAATATCAAGCACATCATCGTCGGTGGC
GCTATCGCCAACTTCACCGATGTCAAGGCAACCTTCAGCGGTATCATCAACGGTTTGCGCGAAAGCAAGTCGAAAGGCTA
CCTCGAAGGCGTCAAAATCTGGGTACGCCGTGGCGGTCCGAACGAGGCTCAGGGCCTTGCCGCCATCAGGAAGCTCCAGG
AGGAAGGCTTCGACATTCACGTCTACGACCGCTCCATGCCGATGACCGATATTGTCGACCTGGCTCTGAAGTCTTGA

Upstream 100 bases:

>100_bases
ACAATTCTTAAATACTTGGAAGTTAAAGCAATATAGTTATATTTAAATTTTACACACTTCTTTTTGTTCGCAAACTACCC
ATAATATAAACATATAGAGC

Downstream 100 bases:

>100_bases
GGGATTTCCTTGCAAGATGTTGAAATTTAAGACTATAGAAACTCATTAAACTCTGATTGAACCGTGAGCATTCTCGCAAA
TAAAGATACCCGGGCGGTCA

Product: citrate lyase, subunit 1

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPKRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLDEAIQASREM
LGAKVGTAEVRQVIVAEMLDHDAEFYVSIIGNRDGAELLISKYGGVDIEDNWDSVRRIQIPLDEHPTIEQLTALAKEAGF
EGEIAERVGKICSRLVLCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDWDARFRHADWDFKPVSEIGRPFTEAEQQI
MDIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPNIKHIIVGG
AIANFTDVKATFSGIINGLRESKSKGYLEGVKIWVRRGGPNEAQGLAAIRKLQEEGFDIHVYDRSMPMTDIVDLALKS

Sequences:

>Translated_398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPKRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLDEAIQASREM
LGAKVGTAEVRQVIVAEMLDHDAEFYVSIIGNRDGAELLISKYGGVDIEDNWDSVRRIQIPLDEHPTIEQLTALAKEAGF
EGEIAERVGKICSRLVLCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDWDARFRHADWDFKPVSEIGRPFTEAEQQI
MDIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPNIKHIIVGG
AIANFTDVKATFSGIINGLRESKSKGYLEGVKIWVRRGGPNEAQGLAAIRKLQEEGFDIHVYDRSMPMTDIVDLALKS
>Mature_397_residues
AKILEGPAMKLFNKWGIPVPNYVVIMDPKRLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKIGLNLDEAIQASREML
GAKVGTAEVRQVIVAEMLDHDAEFYVSIIGNRDGAELLISKYGGVDIEDNWDSVRRIQIPLDEHPTIEQLTALAKEAGFE
GEIAERVGKICSRLVLCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDWDARFRHADWDFKPVSEIGRPFTEAEQQIM
DIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPNIKHIIVGGA
IANFTDVKATFSGIINGLRESKSKGYLEGVKIWVRRGGPNEAQGLAAIRKLQEEGFDIHVYDRSMPMTDIVDLALKS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI38569421, Length=386, Percent_Identity=33.9378238341969, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI38569423, Length=386, Percent_Identity=33.9378238341969, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI11321583, Length=305, Percent_Identity=29.1803278688525, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=27.2020725388601, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI294862256, Length=331, Percent_Identity=27.7945619335347, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1786948, Length=327, Percent_Identity=27.217125382263, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=400, Percent_Identity=33.5, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17557344, Length=424, Percent_Identity=31.3679245283019, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17539378, Length=382, Percent_Identity=28.2722513089005, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567829, Length=321, Percent_Identity=27.1028037383178, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321683, Length=339, Percent_Identity=26.2536873156342, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363475, Length=384, Percent_Identity=33.8541666666667, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281363473, Length=384, Percent_Identity=33.8541666666667, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281363477, Length=384, Percent_Identity=33.8541666666667, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI21356231, Length=385, Percent_Identity=28.3116883116883, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361397, Length=344, Percent_Identity=27.3255813953488, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281361395, Length=344, Percent_Identity=27.3255813953488, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161078106, Length=344, Percent_Identity=27.3255813953488, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24645208, Length=344, Percent_Identity=27.3255813953488, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43777; Mature: 43646

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILEGPAMKLFNKWGIPVPNYVVIMDPKRLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKIGLNLDEAIQASREMLGAKVGTAEVRQVIVAEMLDHDAEFYVSIIGNRDGAELLI
EEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHH
SKYGGVDIEDNWDSVRRIQIPLDEHPTIEQLTALAKEAGFEGEIAERVGKICSRLVLCFD
HHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDWDARFRHADWDFKPVSEIGRPFTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MDIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPPDWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHCCCCEECHHHCCCCCCHHHH
EALTETICRLPNIKHIIVGGAIANFTDVKATFSGIINGLRESKSKGYLEGVKIWVRRGGP
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCC
NEAQGLAAIRKLQEEGFDIHVYDRSMPMTDIVDLALKS
CHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
AKILEGPAMKLFNKWGIPVPNYVVIMDPKRLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKIGLNLDEAIQASREMLGAKVGTAEVRQVIVAEMLDHDAEFYVSIIGNRDGAELLI
EEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHH
SKYGGVDIEDNWDSVRRIQIPLDEHPTIEQLTALAKEAGFEGEIAERVGKICSRLVLCFD
HHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDWDARFRHADWDFKPVSEIGRPFTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MDIDSRIKGSVKFVEVPGGEIALLTAGGGASVFYADAVVARGGTIANYAEYSGDPPDWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHCCCCEECHHHCCCCCCHHHH
EALTETICRLPNIKHIIVGGAIANFTDVKATFSGIINGLRESKSKGYLEGVKIWVRRGGP
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCC
NEAQGLAAIRKLQEEGFDIHVYDRSMPMTDIVDLALKS
CHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA