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The map label for this gene is ycgM [H]

Identifier: 21673869

GI number: 21673869

Start: 980898

End: 981611

Strand: Reverse

Name: ycgM [H]

Synonym: CT1043

Alternate gene names: 21673869

Gene position: 981611-980898 (Counterclockwise)

Preceding gene: 21673872

Following gene: 21673868

Centisome position: 45.55

GC content: 55.6

Gene sequence:

>714_bases
ATGAAAACATTTTCATCTCTGTCAAAACCAGCCACTCATCGCTCGATTTACTGTGTCGGCAAAAACTACCCTGATCACGC
TCGTGAAATGGCTTCATGGGAGACTGACAAGCCCGAGCCGCTGCATGAAAAGGAGCCTGTTATCTTTATGAAACCCGGCA
CGGCGCTTTCTACTGACGGCTGCACCTCGATACCGCGGTTCGAAGGGCAGCTGGTGAGCAGAAACCTTCATTACGAAGGC
GAGCTGGTGCTGCTGATTGGCGCGGACGCCGATGAAGTATCGCTTGCCGATGCTTCGGCGATCATCGCCGGTTACGCCGC
CGGGCTCGATATGACGCTGCGCGATGTACAGCTCGAAGCCAAAAATGCCGGAAATCCCTGGCTGAAAAGCAAGGGGTTTC
GCCAGAGCGCACTCGTCTCGGAGTTCATCGCTCCGGAATCGGCTGGCCCGTGGGCTGAACTCGCCATTTCGCTGCGGCTG
AACGGAGAGCAGAAGCAGTACTCGAAGGTCTCGAAAATGACTTTTTCACCGGCCTATCTGGTGCATTATTTATCGTATAT
TTACGGGCTGCGAGCCGGAGACCTTGTCTTTACCGGCACTCCTGCGGGCGTCGGAAGCGTGCTGCCGGGCGATCGTCTCG
ACGTTTCGCTTGAAACTGCCGACGACCATTCGCAGGCAAAAATACTGGTATCGCTCCAGGCGACTGTTTCCTGA

Upstream 100 bases:

>100_bases
GATATCCCGACTTGTCCCCGTTCCTGCAAAAAGCGAAAATTCGTGAGCCGCATTGTTTTTCTGCAATGAGAATCACCTCT
TCTGTCAACACGTCAATAGC

Downstream 100 bases:

>100_bases
ACTATTCATTCCCCGACCATGAGCACTCTGTTTCTGAACGCAAGACTGCTGAATCCCGCTGAAAATCTCGATACCGTCGG
TTCGATAAAGATAGGCGACG

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKTFSSLSKPATHRSIYCVGKNYPDHAREMASWETDKPEPLHEKEPVIFMKPGTALSTDGCTSIPRFEGQLVSRNLHYEG
ELVLLIGADADEVSLADASAIIAGYAAGLDMTLRDVQLEAKNAGNPWLKSKGFRQSALVSEFIAPESAGPWAELAISLRL
NGEQKQYSKVSKMTFSPAYLVHYLSYIYGLRAGDLVFTGTPAGVGSVLPGDRLDVSLETADDHSQAKILVSLQATVS

Sequences:

>Translated_237_residues
MKTFSSLSKPATHRSIYCVGKNYPDHAREMASWETDKPEPLHEKEPVIFMKPGTALSTDGCTSIPRFEGQLVSRNLHYEG
ELVLLIGADADEVSLADASAIIAGYAAGLDMTLRDVQLEAKNAGNPWLKSKGFRQSALVSEFIAPESAGPWAELAISLRL
NGEQKQYSKVSKMTFSPAYLVHYLSYIYGLRAGDLVFTGTPAGVGSVLPGDRLDVSLETADDHSQAKILVSLQATVS
>Mature_237_residues
MKTFSSLSKPATHRSIYCVGKNYPDHAREMASWETDKPEPLHEKEPVIFMKPGTALSTDGCTSIPRFEGQLVSRNLHYEG
ELVLLIGADADEVSLADASAIIAGYAAGLDMTLRDVQLEAKNAGNPWLKSKGFRQSALVSEFIAPESAGPWAELAISLRL
NGEQKQYSKVSKMTFSPAYLVHYLSYIYGLRAGDLVFTGTPAGVGSVLPGDRLDVSLETADDHSQAKILVSLQATVS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=221, Percent_Identity=39.3665158371041, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI66348062, Length=205, Percent_Identity=40, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI13654274, Length=205, Percent_Identity=40, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI156231349, Length=194, Percent_Identity=30.9278350515464, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI40786394, Length=193, Percent_Identity=32.1243523316062, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787428, Length=211, Percent_Identity=42.1800947867299, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=202, Percent_Identity=34.6534653465347, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324161, Length=240, Percent_Identity=28.3333333333333, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571789, Length=175, Percent_Identity=34.2857142857143, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28572127, Length=196, Percent_Identity=31.1224489795918, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25663; Mature: 25663

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFSSLSKPATHRSIYCVGKNYPDHAREMASWETDKPEPLHEKEPVIFMKPGTALSTDG
CCCHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEECCCC
CTSIPRFEGQLVSRNLHYEGELVLLIGADADEVSLADASAIIAGYAAGLDMTLRDVQLEA
CCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEE
KNAGNPWLKSKGFRQSALVSEFIAPESAGPWAELAISLRLNGEQKQYSKVSKMTFSPAYL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHEEEEEEECCCHHHHHHHHHHCCCHHHH
VHYLSYIYGLRAGDLVFTGTPAGVGSVLPGDRLDVSLETADDHSQAKILVSLQATVS
HHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MKTFSSLSKPATHRSIYCVGKNYPDHAREMASWETDKPEPLHEKEPVIFMKPGTALSTDG
CCCHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEECCCC
CTSIPRFEGQLVSRNLHYEGELVLLIGADADEVSLADASAIIAGYAAGLDMTLRDVQLEA
CCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEE
KNAGNPWLKSKGFRQSALVSEFIAPESAGPWAELAISLRLNGEQKQYSKVSKMTFSPAYL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHEEEEEEECCCHHHHHHHHHHCCCHHHH
VHYLSYIYGLRAGDLVFTGTPAGVGSVLPGDRLDVSLETADDHSQAKILVSLQATVS
HHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]