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The map label for this gene is hppA

Identifier: 21673784

GI number: 21673784

Start: 901592

End: 903844

Strand: Direct

Name: hppA

Synonym: CT0956

Alternate gene names: 21673784

Gene position: 901592-903844 (Clockwise)

Preceding gene: 21673782

Following gene: 21673786

Centisome position: 41.84

GC content: 55.3

Gene sequence:

>2253_bases
ATGTATGGTCTTGTGGTATGCCTTTTTGGCATGATTTTCGGCTTGATTCAGTATCAGGGAATCAACAAGCTGCCCGTTCA
TGCGGCCATGAAGGAGATCAGCGACCTGATCTACGAGACTTGTAAAACCTACCTCATTACCCAGGGCAAATTCATCATTA
TCCTCTGGGCTCTTGTCGCGGCAATCATCGTTGCCTATTTTGGCGGCCTCAACCATCTCGCACCTGACAAGGTTGTCTTC
ATTCTCGCCTGCAGCCTTCTCGGTATTGCCGGCAGTTACACGGTCGCCTGGTTCGGCATGAGGATCAACACCTTCGCCAA
CTCCCGTACCGCATTCGCCAGTCTCGGCGGCAAACCATTTCCGACTTACGCCATTCCGCTTCGCGCCGGCATGAGCATCG
GTATGCTGCTTATCAGCATCGAGCTGTTCGCGATGCTCTGCATCCTGCTCTTCATCCCGGTCGATTATGCTGGCCCATGT
TTCATCGGTTTCGCTATCGGTGAATCGCTTGGCGCTTCGGTGCTGCGTATCGCTGGCGGTATCTTCACCAAGATCGCCGA
TATCGGTTCCGACCTCATGAAGATCGTCTTCAAAATCAAGGAGGACGACGCCCGCAACCCTGGCGTTATCGCCGACTGCA
CGGGTGACAACGCAGGCGATTCCGTCGGGCCGACGGCTGACGGTTTCGAGACCTATGGTGTGACCGGCGTTGCTCTGATC
TCCTTTATCCTGCTCGCCATCAAGGATCCTTCGATCCAGGTTTCACTGCTCGTCTGGATTTTCGCCATGCGTCTCGTCAT
GATTGTTGCCAGCGCCGTGTCTTACTGGGTCAATGACGCCCTCGCCAAGATGAAGTATGGCAACGCCGACGAAATGAACT
TCGAGAAACCGCTGATCACTCTCGTCTGGCTTACCTCGATCGTTTCCATCGTCCTGACCTACATCGCATCCTATATGCTG
ATTGCCCAGCTTGGCGACGGCACGATGTGGTGGAAGCTTGCCTCGATCATCACCTGCGGCACGATTGCCGGCGCGCTCAT
TCCCGAGCTGGTCGACAGGTTCACCTCAACCGAGTGCGCCTTTGTTCGCAACGTCGTGCAGTGCTCCAAAGAGGGTGGTG
CTGCGTTGAACATCCTTTCCGGTCTCGTTGCCGGTAACTTCAGCGCCTACTGGATGGGCCTGGCGATTATCGTCCTTATG
GGGGCAGCCTTCGGATTCAGCACTCTCGGTCTTGATGTGATGATGCTCGCGCCTTCCGTGTTCGCTTTCGGTCTCGTTGC
CTTCGGCTTCCTCAGCATGGGCCCGGTCACCATCGCGGTTGACTCTTACGGGCCGGTTACCGATAACGCGCAGTCGGTTT
ATGAACTGTCGCTGATCGAAACCCTTCCGAACATCTCGAATAGCATTGAAAGCGAGTTCGGTTTCAAGCCCGATTTCGAG
AACGCCAAGCGTTACCTCGAAGCCAACGATGGCGCAGGCAACACCTTCAAGGCGACCGCCAAGCCGGTGCTGATCGGTAC
CGCCGTGGTCGGTTCGACGACGATGATTTTCTCGATCATCATGATTCTGACCGGCGGCCTTGCCGATACAGGCGCCATTG
CGAAGCTCTCCATCCTGTGGCCCCCGTTCCTGCTCGGCTTGCTGATGGGCGGCGCGGTTATCTACTGGTTCACCGGCGCT
TCGATGAACGCCGTGACTACCGGCGCGTACTATGCCGTCGCGTTCATCAAAAAGAACATCAAGCTTGATGGCGTTACCAA
GGCTTCGACAGAAGACAGCAAGAAGGTTGTCGAAATCTGCACCAGGTTTGCGCAGAAAGGCATGATCAACCTCTTCCTGA
CTATCTTCTTCAGTACGCTGGCCTTTGCCTGTCTCGAATCGTACCTCTTCATCGGCTACCTGATCTCCATCGCGCTGTTC
GGTCTGTATCAGGCCATCTTCATGGCCAACGCCGGCGGCGCATGGGATAATGCCAAGAAAGTGGTTGAGACCGAACTTCA
TGCCAAAGGCACCGAACTGCACGATGCAAGCGTGGTCGGCGATACGGTGGGCGATCCATTCAAGGATACCTCTTCGGTTG
CGCTGAACCCGATCATCAAGTTCACCACACTGTTCGGTCTGCTTGCCATCGAGCTGGCGATCAAGCTGCCGACTACGATT
TCTGTTTCACTGGCGGTTGTTTTCTTCCTGCTTTCGCTTGTTTTTGTACACCGCTCCTTCTTCTCCATGAGGATCGCCGT
GGACAAGGACTGA

Upstream 100 bases:

>100_bases
GCTTTCAGCGTCACAAGCGTATGCAAGCGAGGCCGATCTGGTATTGCCGGACTTAAGCTCGGTATCCTTTTTGGGCGGAA
TACCTGGCCACACGTTGTTG

Downstream 100 bases:

>100_bases
GCTATATTTCCGTATTAAACATTACCTGCCGGAAACGGCAGGTTTTTCTTGGGGCCGCAGCAATGTGGCCTCGGCTGTTT
TATGGAGGCTATCGTTTTTA

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVAAIIVAYFGGLNHLAPDKVVF
ILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPFPTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPC
FIGFAIGESLGASVLRIAGGIFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALI
SFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLITLVWLTSIVSIVLTYIASYML
IAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECAFVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLM
GAAFGFSTLGLDVMMLAPSVFAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFE
NAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILWPPFLLGLLMGGAVIYWFTGA
SMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEICTRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALF
GLYQAIFMANAGGAWDNAKKVVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTI
SVSLAVVFFLLSLVFVHRSFFSMRIAVDKD

Sequences:

>Translated_750_residues
MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVAAIIVAYFGGLNHLAPDKVVF
ILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPFPTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPC
FIGFAIGESLGASVLRIAGGIFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALI
SFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLITLVWLTSIVSIVLTYIASYML
IAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECAFVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLM
GAAFGFSTLGLDVMMLAPSVFAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFE
NAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILWPPFLLGLLMGGAVIYWFTGA
SMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEICTRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALF
GLYQAIFMANAGGAWDNAKKVVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTI
SVSLAVVFFLLSLVFVHRSFFSMRIAVDKD
>Mature_750_residues
MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVAAIIVAYFGGLNHLAPDKVVF
ILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPFPTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPC
FIGFAIGESLGASVLRIAGGIFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALI
SFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLITLVWLTSIVSIVLTYIASYML
IAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECAFVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLM
GAAFGFSTLGLDVMMLAPSVFAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFE
NAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILWPPFLLGLLMGGAVIYWFTGA
SMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEICTRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALF
GLYQAIFMANAGGAWDNAKKVVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTI
SVSLAVVFFLLSLVFVHRSFFSMRIAVDKD

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPPA_CHLTE (Q8KDT8)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661849.1
- GeneID:   1007080
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0956
- NMPDR:   fig|194439.1.peg.943
- TIGR:   CT0956
- HOGENOM:   HBG309781
- OMA:   GSDLMKI
- ProtClustDB:   PRK00733
- BioCyc:   CTEP194439:CT_0956-MONOMER
- BRENDA:   3.6.1.1
- HAMAP:   MF_01129
- InterPro:   IPR004131
- PIRSF:   PIRSF001265

Pfam domain/function: PF03030 H_PPase

EC number: =3.6.1.1

Molecular weight: Translated: 80371; Mature: 80371

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd28ae5c)-; HASH(0xdcf3510)-; HASH(0xd275d84)-; HASH(0xb577b48)-; HASH(0xdcb5be0)-; HASH(0xd4f9a68)-; HASH(0xd6e7ec4)-; HASH(0x972e8e4)-; HASH(0xd118b68)-; HASH(0xdcb5d90)-; HASH(0xc9d485c)-; HASH(0xd80f0e4)-; HASH(0xb38ead0)-; HASH(0xd5cd090)-; HASH(0xdc3a128)-; HASH(0xb3c0b70)-; HASH(0xd64614c)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
AIIVAYFGGLNHLAPDKVVFILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHCCCCHHHHHCCCCCC
PTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPCFIGFAIGESLGASVLRIAGG
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHH
SFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLIT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
LVWLTSIVSIVLTYIASYMLIAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLMGAAFGFSTLGLDVMMLAPSV
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFE
HHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHH
NAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILW
HHHHHHCCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHH
PPFLLGLLMGGAVIYWFTGASMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEIC
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHH
TRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALFGLYQAIFMANAGGAWDNAKK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTI
HHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVSLAVVFFLLSLVFVHRSFFSMRIAVDKD
HHHHHHHHHHHHHHHHHHHHHHEEEEEECH
>Mature Secondary Structure
MYGLVVCLFGMIFGLIQYQGINKLPVHAAMKEISDLIYETCKTYLITQGKFIIILWALVA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
AIIVAYFGGLNHLAPDKVVFILACSLLGIAGSYTVAWFGMRINTFANSRTAFASLGGKPF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHCCCCHHHHHCCCCCC
PTYAIPLRAGMSIGMLLISIELFAMLCILLFIPVDYAGPCFIGFAIGESLGASVLRIAGG
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPTADGFETYGVTGVALI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHH
SFILLAIKDPSIQVSLLVWIFAMRLVMIVASAVSYWVNDALAKMKYGNADEMNFEKPLIT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
LVWLTSIVSIVLTYIASYMLIAQLGDGTMWWKLASIITCGTIAGALIPELVDRFTSTECA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FVRNVVQCSKEGGAALNILSGLVAGNFSAYWMGLAIIVLMGAAFGFSTLGLDVMMLAPSV
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FAFGLVAFGFLSMGPVTIAVDSYGPVTDNAQSVYELSLIETLPNISNSIESEFGFKPDFE
HHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHH
NAKRYLEANDGAGNTFKATAKPVLIGTAVVGSTTMIFSIIMILTGGLADTGAIAKLSILW
HHHHHHCCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHH
PPFLLGLLMGGAVIYWFTGASMNAVTTGAYYAVAFIKKNIKLDGVTKASTEDSKKVVEIC
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHH
TRFAQKGMINLFLTIFFSTLAFACLESYLFIGYLISIALFGLYQAIFMANAGGAWDNAKK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VVETELHAKGTELHDASVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAIELAIKLPTTI
HHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVSLAVVFFLLSLVFVHRSFFSMRIAVDKD
HHHHHHHHHHHHHHHHHHHHHHEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901