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The map label for this gene is cobP [H]

Identifier: 21673773

GI number: 21673773

Start: 893350

End: 893868

Strand: Direct

Name: cobP [H]

Synonym: CT0945

Alternate gene names: 21673773

Gene position: 893350-893868 (Clockwise)

Preceding gene: 21673772

Following gene: 21673774

Centisome position: 41.46

GC content: 57.8

Gene sequence:

>519_bases
ATGCCTGAAGTAATCTATGTGACCGGCGGAGCCCGGAGTGGCAAGAGCTGCTATGCGCTGAAGCTGGCCGAACGATACAA
GTGTCGGGTGTTTCTTGCTACTGCCGAGGCGTTCGATGGGGAGATGCAGCGTCGTATCGACAAGCACAAACAGGAGCGCG
ACGAGCGCTTTACGACGGTGGAGGAGCCGGTGTATCTCGACAAAGCGCTGCGCGCTTTACCCGACGGGACAGAGGTGGTG
CTGGTCGATTGCCTGACCGTGTGGCTGGGAAACATGATGCACTATCTCGGCGATGAAGCGGCGATCAACGAGCGGATCGA
CGCCCTGCTCGATGTACTGAAGAATCCGCCGTGCGACATCATTTTTGTTTCCAATGAAGTTGGTATGGGGATCGTGCCCG
AAAACGCGATGGCACGCGAGTTCCGTGACCTGGCCGGCACGCTCAATCGCAAGGTGGCCGAACGCGCCACGCAGGCGTAT
TTGCTGTGCAGCGGTTTGCCGCTTGTTTTGAAAAAGTAG

Upstream 100 bases:

>100_bases
GTTCACGCTGGAGATTTTCTCGGAAGCAGATTTTTTGTCGTCAGTCGAGACGCTGGAGCGGTTTTCGTCATGACTCTTCA
ATCGCATAATTATTGCACCT

Downstream 100 bases:

>100_bases
TAACCAAAAAAGAGTAACCAAAAAAAAATCAATCGTTATGACCGACCGTTTTCAGCAGCTTCTGGCTTCTATCAAGCCTG
TCGATATGAACCTAACCTCC

Product: cobalamin biosynthesis protein CobP

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPEVIYVTGGARSGKSCYALKLAERYKCRVFLATAEAFDGEMQRRIDKHKQERDERFTTVEEPVYLDKALRALPDGTEVV
LVDCLTVWLGNMMHYLGDEAAINERIDALLDVLKNPPCDIIFVSNEVGMGIVPENAMAREFRDLAGTLNRKVAERATQAY
LLCSGLPLVLKK

Sequences:

>Translated_172_residues
MPEVIYVTGGARSGKSCYALKLAERYKCRVFLATAEAFDGEMQRRIDKHKQERDERFTTVEEPVYLDKALRALPDGTEVV
LVDCLTVWLGNMMHYLGDEAAINERIDALLDVLKNPPCDIIFVSNEVGMGIVPENAMAREFRDLAGTLNRKVAERATQAY
LLCSGLPLVLKK
>Mature_171_residues
PEVIYVTGGARSGKSCYALKLAERYKCRVFLATAEAFDGEMQRRIDKHKQERDERFTTVEEPVYLDKALRALPDGTEVVL
VDCLTVWLGNMMHYLGDEAAINERIDALLDVLKNPPCDIIFVSNEVGMGIVPENAMAREFRDLAGTLNRKVAERATQAYL
LCSGLPLVLKK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=40, Blast_Score=131, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19296; Mature: 19164

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVIYVTGGARSGKSCYALKLAERYKCRVFLATAEAFDGEMQRRIDKHKQERDERFTTV
CCCEEEEECCCCCCCCCCEEEHHHHCEEEEEEEEHHHHCHHHHHHHHHHHHHHHHHCCHH
EEPVYLDKALRALPDGTEVVLVDCLTVWLGNMMHYLGDEAAINERIDALLDVLKNPPCDI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCE
IFVSNEVGMGIVPENAMAREFRDLAGTLNRKVAERATQAYLLCSGLPLVLKK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure 
PEVIYVTGGARSGKSCYALKLAERYKCRVFLATAEAFDGEMQRRIDKHKQERDERFTTV
CCEEEEECCCCCCCCCCEEEHHHHCEEEEEEEEHHHHCHHHHHHHHHHHHHHHHHCCHH
EEPVYLDKALRALPDGTEVVLVDCLTVWLGNMMHYLGDEAAINERIDALLDVLKNPPCDI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCE
IFVSNEVGMGIVPENAMAREFRDLAGTLNRKVAERATQAYLLCSGLPLVLKK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]