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The map label for this gene is cobT [H]

Identifier: 21673774

GI number: 21673774

Start: 893906

End: 894967

Strand: Direct

Name: cobT [H]

Synonym: CT0946

Alternate gene names: 21673774

Gene position: 893906-894967 (Clockwise)

Preceding gene: 21673773

Following gene: 21673775

Centisome position: 41.48

GC content: 61.21

Gene sequence:

>1062_bases
ATGACCGACCGTTTTCAGCAGCTTCTGGCTTCTATCAAGCCTGTCGATATGAACCTAACCTCCACCGTCAAGGCGCATCT
CGATGATCTGACCAAACCGCAGGGGAGCCTTGGGCGGCTCGAAGAGATTGTGATGAAGTATTGCATCGCCACCGGCACGA
CGAAGCCTTCGCTGTCCAAAAAGAAGGTGTTCTGCTTCGCGGGGGATCATGGTGTGGCTGCCGAGGGCGTTTCGGCCTTT
CCTGCCGAGGTGACGCCGCAGATGGTCTATAACATGCTTGGCGGCGGGGCGGCCATCAACGTGCTGTCGCGCCACGCCGG
GGCCGATCTCGAAGTGGTCGATATGGGGGTGAATCACGACTTCGCGGAGCATCCGATGCTGCGCCGATGCAAGGTGAAGC
ACGGTTCGGCGAACATGGCCGAAGGTCCGGCAATGAGTATCGAGGAGACCTTGCAGGCGATCATGGCGGGTGCGGAACTG
GCCATCGAGGCGCGGAACCAGGGGTACGAATTGCTCGCTACCGGTGAGATGGGCATTGCCAACACCACGCCTGCAACGGC
GCTCTACGCCACGCTGCTCGGGTTGCCGGTCGAAGCGATCACCGGTCGCGGCACGGGCATCGACGACGAGCGACTTCATC
ACAAAGTCGCGGTGATCGAAAAGGCAATCGAGGTCAATCGCGCCAACCTCGCGACGCCGCTCGAAGTGCTCGCCGCGCTG
GGCGGCTTCGAGATTGCAGGCATCTGCGGCCTGATTCTCGGTGCGGCGTCGGTTGGGATGCCGGTTGTGGTCGATGGTTT
CATCTCGAGCTCGGCGGCGGTGTGTGCCATCAAGCTCTCGTGCACGGTGAGCGATTACCTCTTTTTCAGCCACCTCTCCA
ACGAACAGGGCCACCGCGCGGTGATGCAGAAGCTCGGTGCGCGCCCGATCCTCGACCTTGACCTGCGGCTCGGTGAGGGC
ACCGGTGCGGCGATGGCTATGCAGGTGATCGAGGCGTCGGTGAAAATCTACAACGAAATGGCTACCTTCAGTTCGGCGGG
AGTTTCCGGCAAAAACGACTGA

Upstream 100 bases:

>100_bases
GCCGAACGCGCCACGCAGGCGTATTTGCTGTGCAGCGGTTTGCCGCTTGTTTTGAAAAAGTAGTAACCAAAAAAGAGTAA
CCAAAAAAAAATCAATCGTT

Downstream 100 bases:

>100_bases
TAACATGGACTCTTTTCTCGACATACAGCGGAAGAAAGCCGATGCTGACAGTAAGTTCATCGACTGCAACGGCTTCCGGG
TGCACTACAAGCGCTACGGC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTDRFQQLLASIKPVDMNLTSTVKAHLDDLTKPQGSLGRLEEIVMKYCIATGTTKPSLSKKKVFCFAGDHGVAAEGVSAF
PAEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHDFAEHPMLRRCKVKHGSANMAEGPAMSIEETLQAIMAGAEL
AIEARNQGYELLATGEMGIANTTPATALYATLLGLPVEAITGRGTGIDDERLHHKVAVIEKAIEVNRANLATPLEVLAAL
GGFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCTVSDYLFFSHLSNEQGHRAVMQKLGARPILDLDLRLGEG
TGAAMAMQVIEASVKIYNEMATFSSAGVSGKND

Sequences:

>Translated_353_residues
MTDRFQQLLASIKPVDMNLTSTVKAHLDDLTKPQGSLGRLEEIVMKYCIATGTTKPSLSKKKVFCFAGDHGVAAEGVSAF
PAEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHDFAEHPMLRRCKVKHGSANMAEGPAMSIEETLQAIMAGAEL
AIEARNQGYELLATGEMGIANTTPATALYATLLGLPVEAITGRGTGIDDERLHHKVAVIEKAIEVNRANLATPLEVLAAL
GGFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCTVSDYLFFSHLSNEQGHRAVMQKLGARPILDLDLRLGEG
TGAAMAMQVIEASVKIYNEMATFSSAGVSGKND
>Mature_352_residues
TDRFQQLLASIKPVDMNLTSTVKAHLDDLTKPQGSLGRLEEIVMKYCIATGTTKPSLSKKKVFCFAGDHGVAAEGVSAFP
AEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHDFAEHPMLRRCKVKHGSANMAEGPAMSIEETLQAIMAGAELA
IEARNQGYELLATGEMGIANTTPATALYATLLGLPVEAITGRGTGIDDERLHHKVAVIEKAIEVNRANLATPLEVLAALG
GFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCTVSDYLFFSHLSNEQGHRAVMQKLGARPILDLDLRLGEGT
GAAMAMQVIEASVKIYNEMATFSSAGVSGKND

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=346, Percent_Identity=39.5953757225434, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37055; Mature: 36924

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRFQQLLASIKPVDMNLTSTVKAHLDDLTKPQGSLGRLEEIVMKYCIATGTTKPSLSK
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KKVFCFAGDHGVAAEGVSAFPAEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHD
CEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCC
FAEHPMLRRCKVKHGSANMAEGPAMSIEETLQAIMAGAELAIEARNQGYELLATGEMGIA
HHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHEEEECCCCEEEEEECCCCCC
NTTPATALYATLLGLPVEAITGRGTGIDDERLHHKVAVIEKAIEVNRANLATPLEVLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GGFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCTVSDYLFFSHLSNEQGHRA
CCCHHHHHHHHHHHHHHCCCCEEEECHHCCCCEEEEEEEEECHHHHHHHHHHCCCCHHHH
VMQKLGARPILDLDLRLGEGTGAAMAMQVIEASVKIYNEMATFSSAGVSGKND
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDRFQQLLASIKPVDMNLTSTVKAHLDDLTKPQGSLGRLEEIVMKYCIATGTTKPSLSK
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KKVFCFAGDHGVAAEGVSAFPAEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHD
CEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCC
FAEHPMLRRCKVKHGSANMAEGPAMSIEETLQAIMAGAELAIEARNQGYELLATGEMGIA
HHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHEEEECCCCEEEEEECCCCCC
NTTPATALYATLLGLPVEAITGRGTGIDDERLHHKVAVIEKAIEVNRANLATPLEVLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GGFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCTVSDYLFFSHLSNEQGHRA
CCCHHHHHHHHHHHHHHCCCCEEEECHHCCCCEEEEEEEEECHHHHHHHHHHCCCCHHHH
VMQKLGARPILDLDLRLGEGTGAAMAMQVIEASVKIYNEMATFSSAGVSGKND
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA