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The map label for this gene is cbiP

Identifier: 21673766

GI number: 21673766

Start: 886117

End: 887619

Strand: Direct

Name: cbiP

Synonym: CT0938

Alternate gene names: 21673766

Gene position: 886117-887619 (Clockwise)

Preceding gene: 21673765

Following gene: 21673767

Centisome position: 41.12

GC content: 60.28

Gene sequence:

>1503_bases
ATGACCAATATCGCCATACTCGGTACCGCCTCGGACGTCGGCAAGAGCATCGTGGCCACCGCGCTGTGCCGCATTTTCAG
CAACGCGGGAGTCGATGTGGCGCCCTACAAGGCGCAGAACATGTCGAATAATTCAGGCGTCACGCCGGATGGTTTCGAGA
TGGGCCGGGCGCAGATCGTGCAGGCGCAGGCCGCTCGTGTCGCGCCCCACGCCGACATGAATCCGGTGCTGCTCAAGCCC
AACACCGACACCGGCGCGCAGGTTGTGCTGCAAGGCAAAGTGTGCGCGGACAAGAGCGCTCGCGAATATTTCGGCGACAC
GCAGCGCTGGGCCGAGGCGGCCTTCGAGAGCCTCGACCGGCTTATGGTGCGGCACGAATTGCTGGTGATCGAGGGGGCGG
GATCGTGCGCGGAGATGAATCTCTACCAGCGCGATTTCGTGAACTTCAAAACCGCCCGACGTGCCGGAGCAGCAGTGATT
CTCGTAGCGGACATCGACCGTGGTGGCGTCTTCGCCCAGGTGGTGGGCACGCTTGCTGTGATTCCGCCGGAGGATCGTGC
GCTGGTGAAAGGCGTCATTATCAACCGCTTCCGGGGTGACAAATCACTCTTCGAGGGTGGCGTAAAAATGCTCGAATCGA
TGACCGGCGTGCCGGTGCTTGGCGTCATCCCTTATTTTCGCGGCTTCACCATTGATGCTGAGGACGCTGTCCCATTGTCG
TCCGTGGTCGATCCGAAGCAGGAGCCGTCCGGAGACAAGATCGGCGTCGCGGCGATCTACTTTCCGCATATCTCCAACTT
CACCGACCTTGCGCCGCTGGAGCGCGATCCCTCGGTCGAGCTGCACTACCTCCACCGCCCGAAGTCGCTTGATGGTTACA
AAGCGCTGATTCTGCCAGGCTCGAAGAACGTGCGCGGTGACCTCGCATGGCTCGAAACAATGGGCTGGCGCGACGAGATC
GAAAAGTTTCGCAAGCGGGGAGGCATCATTGTCGGTCTCTGTGGTGGCTACCAGATGCTCGGCGCGTCTATCGCCGATCC
GTACGGCGTTGAGGGCGCTCCGGGCGCGAGCGCGGGTCTCGCGATGTTGCCGGTCGAGACGGTGCTGGAACGCGAAAAAG
CGCTCTGTAACAGCGTCGGTAAAATTGCCGGAACACCATTTTTTGTAAGCGGTTACGAAATTCATATGGGCCGGACGGCA
CTTGAACCGGGTGCGTCGCCACTCCTCGAAGTGACGGAGCGCAACGGCGTCGCAACCGACGATTTCGACGGCGCGAAGAG
CGCCGACGGTCAGGTGACGGGTACCTATTTCCACGGCTTTTTCGACCGTCCGGAAGTCCGTACCTGGTTCCTGCGCCTGC
TGGACGGGGGTTACGAATCGCCAAGGGGAGCATCCGTTGCTGATCCATTCGAGCTGCTTGCCAAGCATTTCTCGGAAAAT
CTCGATCTTGAGAAGTTGTTTGCTATTGCCGGTCTTTCGGTCAAAGGGGAGAAAGAGTCATGA

Upstream 100 bases:

>100_bases
TCCACGAAGCGCCGGAGCTGGAGCAGGCCGGTTGGCTGCCGCGCCTTGCACTCGACGACCTGCTGCACCAGGAGCAATGG
TAACTGATTTCGTAACGCCC

Downstream 100 bases:

>100_bases
ATCACGATCATCTGCTGGCACATCGCCACGGCGACCGTTCGGGCGACAGGCTTGCGAGTGCCATTTCGCTCGACTTCAGC
GTCAATCTCGCACCGATCGA

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIVQAQAARVAPHADMNPVLLKP
NTDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDRLMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVI
LVADIDRGGVFAQVVGTLAVIPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLS
SVVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPGSKNVRGDLAWLETMGWRDEI
EKFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGLAMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTA
LEPGASPLLEVTERNGVATDDFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSEN
LDLEKLFAIAGLSVKGEKES

Sequences:

>Translated_500_residues
MTNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIVQAQAARVAPHADMNPVLLKP
NTDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDRLMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVI
LVADIDRGGVFAQVVGTLAVIPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLS
SVVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPGSKNVRGDLAWLETMGWRDEI
EKFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGLAMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTA
LEPGASPLLEVTERNGVATDDFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSEN
LDLEKLFAIAGLSVKGEKES
>Mature_499_residues
TNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIVQAQAARVAPHADMNPVLLKPN
TDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDRLMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVIL
VADIDRGGVFAQVVGTLAVIPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLSS
VVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPGSKNVRGDLAWLETMGWRDEIE
KFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGLAMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTAL
EPGASPLLEVTERNGVATDDFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSENL
DLEKLFAIAGLSVKGEKES

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_CHLTE (Q8KDV6)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661831.1
- ProteinModelPortal:   Q8KDV6
- SMR:   Q8KDV6
- GeneID:   1007109
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0938
- NMPDR:   fig|194439.1.peg.925
- TIGR:   CT0938
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- BioCyc:   CTEP194439:CT_0938-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: 6.3.5.10

Molecular weight: Translated: 53716; Mature: 53585

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 334-334 ACT_SITE 438-438

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIV
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QAQAARVAPHADMNPVLLKPNTDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDR
HHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHH
LMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVILVADIDRGGVFAQVVGTLAV
HHHHHEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHEEE
IPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLS
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCCCCCHH
SVVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPG
HHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECC
SKNVRGDLAWLETMGWRDEIEKFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGL
CCCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCE
AMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTALEPGASPLLEVTERNGVATD
EECHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCCCCCCCCCHHHHHHHCCCCCCC
DFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSEN
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
LDLEKLFAIAGLSVKGEKES
CCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIV
CCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QAQAARVAPHADMNPVLLKPNTDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDR
HHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHH
LMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVILVADIDRGGVFAQVVGTLAV
HHHHHEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHEEE
IPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLS
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCCCCCHH
SVVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPG
HHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECC
SKNVRGDLAWLETMGWRDEIEKFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGL
CCCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCE
AMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTALEPGASPLLEVTERNGVATD
EECHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCCCCCCCCCHHHHHHHCCCCCCC
DFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSEN
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
LDLEKLFAIAGLSVKGEKES
CCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901