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The map label for this gene is amy [H]

Identifier: 21673585

GI number: 21673585

Start: 728793

End: 730748

Strand: Direct

Name: amy [H]

Synonym: CT0755

Alternate gene names: 21673585

Gene position: 728793-730748 (Clockwise)

Preceding gene: 21673584

Following gene: 21673586

Centisome position: 33.82

GC content: 59.97

Gene sequence:

>1956_bases
ATGACAAACCCCGATTCCCCAGCATTATCGCCGGTCGAACGCAGCCTCGCAGAAATTCGGCTTGCTGAACTGACCGCAGC
CAAAACCTGCTATTCCTCCCCGGCCACCTGGGAGGATGAGGTGCTCTATTTCCTTATGCTCGACCGGTTTTCGGACTGCA
GGGAGCATGGCGGCTTCAATGATGTCAGCGGAGCCCCGGTTGTTGCGGACGGGACGCGCACCACGCTGCTGTTCCGCATC
GAAGCCGATGCGAACAACGCGGACTGGCAGCAGTGGTTCGAGGCGGGCCGGGGGTGGTGCGGCGGCACGATTGCCGGTAT
GCGCGACAAGCTTGGTTACCTGAAGCGGCTCGGCGTGACGGCGATCTGGGTCAGCCCGGTGTTCCGGCAGGTGACCGGCA
GCGACTCCTACCACGGCTACGGCATTCAGAACTTTCTCGATGTCGATCCCCATTTCGGCACACGCGAAGAGCTGCGTGAT
TTCGTTGCTGACGCGCACCAGCTCGGAATCCGGGTGATCCTTGACATCATCCTCAACCATGCGGGCGACGTCTTCAGCTA
TCATGACAATCAGCCCTACTTCTATTACCAGGGCTGGCAGTGGCCGGTCAAGGGGTACAGGCTGAATCAGGGCGATGCGG
GCAGCATTCCGTTCAGCGACGGAGAGGCTCATCTGGAAATCTCGATGGAGGCTGCGATCTGGCCGGTGGAGTTCCAGAGC
GAGACGACCTGGACGATGAAGGGCGAAATCCGCAACTGGGACGTGTTTCCGGAGTACCTCCAAGGTGATTTTTGCTCGCT
CAAGGATATCGATCACGGTTGGGCGCCGGACGACCCGGCAGAGAGCTGGGACCTCGAAAAGCGCATCAGCCTGTTCCGCC
CCTCGGCGGCGCTTGATCACCTTATCAAGGTTTATCGATTCTGGATGGCGTATGCCGACATCGACGGCTTCCGGCTCGAC
ACGGTCAAGCACATGGAGCCGGGCGCGGTGCGCTACTTCGCCTCGGCGATCCACGAATTCGCGCAGACGCTCGGCAAGGA
GAACTTTCCGATCATTGGTGAAATTACCGGTGGGCGCTCTTACGCGATGCAGATTCTTGATGTGACGGGTCTCGATGCAG
CGCTTGGCATCGGCGACCTGCCGGACAAGCTCGAATTTCTTGTCAAGGGCTGGCGCAGTCCCGGCAATCCGGATACCTCC
GAGCAGGAGGGGTATTTCGATCTCTTCTGTAACAGTCTGCTCGATGGCAAGAACAGCCATCAGTGGTACTCGAAGCACAT
CGTTACCATGATCGACGATCACGATCAGGTGGGCGAGCAGCGCAAATACCACTTCTGCGGCGATTCGCCCGAGGGCCGGA
AACTGCTGAAAGCGGCGCTGGGGCTGAACCTCGCCACCGAAGGGATCAGTTGCATCTACTATGGCACCGAGCAGGCGTTC
AACGGAGCCGATCCGCGCAGCGACGACCACTCATGGGGTGACGTGTTCCTGCGCGAGTGCATGTTCGGCGGGCCGTTCGG
ATCGCTGCAAAGCACGGGCCGGCATTTTTTCAACGAGGAGCATGAGGTCTATCGCTTCGCTGGCAGGCTGGCGGAGTTCC
GCAAAAGCGAAATTGCCCTGCGCCGTGGACGCCAGTATTTGCGGAAGGTTTCCGCGACGGGCAGCGAGGACGATTTCGTC
TATCCCCAGCCGGTTAATGGCGAGATGCACTGGGTGGTCGCCTGGTCGCGCATTTTCGCCGAGACGGAGTGCCTGTGTGC
CATCAACACAAGCCTCGAACGCGAGCTGACAGTATGGGCTGTGGTTGATCACCAGCTCAACCCGCCCGGCAAAACGATGC
GCTGCGTCTTTTCGTCATCACCGGAGCAGGAAGGCGAAGAGATAAAGGCAGGGCCTGTCTGCGGCTCGGCGGTGAAAATC
ACGGTGCCACCAGGCGGCTTCGTCATCTATCGCTGA

Upstream 100 bases:

>100_bases
TGTGATTTGAGTGGTATTACGTCTGTACTTCGTATCTTTTTCTCACATTGTTTCCCCTTGGTTTTTCGCGTTCCTCACTC
ATAACGCAAACCGCAAATCC

Downstream 100 bases:

>100_bases
GATGCGGTGTTTGTCAGGCTAATCATGCCACCTGGCGGAGTCGGGAGTTTTTCCGGCCCCGCCTTTTTTGTTACTATTGT
TGTCAGATAAATGGTATTGC

Product: alpha-amylase

Products: NA

Alternate protein names: 1,4-alpha-D-glucan glucanohydrolase [H]

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MTNPDSPALSPVERSLAEIRLAELTAAKTCYSSPATWEDEVLYFLMLDRFSDCREHGGFNDVSGAPVVADGTRTTLLFRI
EADANNADWQQWFEAGRGWCGGTIAGMRDKLGYLKRLGVTAIWVSPVFRQVTGSDSYHGYGIQNFLDVDPHFGTREELRD
FVADAHQLGIRVILDIILNHAGDVFSYHDNQPYFYYQGWQWPVKGYRLNQGDAGSIPFSDGEAHLEISMEAAIWPVEFQS
ETTWTMKGEIRNWDVFPEYLQGDFCSLKDIDHGWAPDDPAESWDLEKRISLFRPSAALDHLIKVYRFWMAYADIDGFRLD
TVKHMEPGAVRYFASAIHEFAQTLGKENFPIIGEITGGRSYAMQILDVTGLDAALGIGDLPDKLEFLVKGWRSPGNPDTS
EQEGYFDLFCNSLLDGKNSHQWYSKHIVTMIDDHDQVGEQRKYHFCGDSPEGRKLLKAALGLNLATEGISCIYYGTEQAF
NGADPRSDDHSWGDVFLRECMFGGPFGSLQSTGRHFFNEEHEVYRFAGRLAEFRKSEIALRRGRQYLRKVSATGSEDDFV
YPQPVNGEMHWVVAWSRIFAETECLCAINTSLERELTVWAVVDHQLNPPGKTMRCVFSSSPEQEGEEIKAGPVCGSAVKI
TVPPGGFVIYR

Sequences:

>Translated_651_residues
MTNPDSPALSPVERSLAEIRLAELTAAKTCYSSPATWEDEVLYFLMLDRFSDCREHGGFNDVSGAPVVADGTRTTLLFRI
EADANNADWQQWFEAGRGWCGGTIAGMRDKLGYLKRLGVTAIWVSPVFRQVTGSDSYHGYGIQNFLDVDPHFGTREELRD
FVADAHQLGIRVILDIILNHAGDVFSYHDNQPYFYYQGWQWPVKGYRLNQGDAGSIPFSDGEAHLEISMEAAIWPVEFQS
ETTWTMKGEIRNWDVFPEYLQGDFCSLKDIDHGWAPDDPAESWDLEKRISLFRPSAALDHLIKVYRFWMAYADIDGFRLD
TVKHMEPGAVRYFASAIHEFAQTLGKENFPIIGEITGGRSYAMQILDVTGLDAALGIGDLPDKLEFLVKGWRSPGNPDTS
EQEGYFDLFCNSLLDGKNSHQWYSKHIVTMIDDHDQVGEQRKYHFCGDSPEGRKLLKAALGLNLATEGISCIYYGTEQAF
NGADPRSDDHSWGDVFLRECMFGGPFGSLQSTGRHFFNEEHEVYRFAGRLAEFRKSEIALRRGRQYLRKVSATGSEDDFV
YPQPVNGEMHWVVAWSRIFAETECLCAINTSLERELTVWAVVDHQLNPPGKTMRCVFSSSPEQEGEEIKAGPVCGSAVKI
TVPPGGFVIYR
>Mature_650_residues
TNPDSPALSPVERSLAEIRLAELTAAKTCYSSPATWEDEVLYFLMLDRFSDCREHGGFNDVSGAPVVADGTRTTLLFRIE
ADANNADWQQWFEAGRGWCGGTIAGMRDKLGYLKRLGVTAIWVSPVFRQVTGSDSYHGYGIQNFLDVDPHFGTREELRDF
VADAHQLGIRVILDIILNHAGDVFSYHDNQPYFYYQGWQWPVKGYRLNQGDAGSIPFSDGEAHLEISMEAAIWPVEFQSE
TTWTMKGEIRNWDVFPEYLQGDFCSLKDIDHGWAPDDPAESWDLEKRISLFRPSAALDHLIKVYRFWMAYADIDGFRLDT
VKHMEPGAVRYFASAIHEFAQTLGKENFPIIGEITGGRSYAMQILDVTGLDAALGIGDLPDKLEFLVKGWRSPGNPDTSE
QEGYFDLFCNSLLDGKNSHQWYSKHIVTMIDDHDQVGEQRKYHFCGDSPEGRKLLKAALGLNLATEGISCIYYGTEQAFN
GADPRSDDHSWGDVFLRECMFGGPFGSLQSTGRHFFNEEHEVYRFAGRLAEFRKSEIALRRGRQYLRKVSATGSEDDFVY
PQPVNGEMHWVVAWSRIFAETECLCAINTSLERELTVWAVVDHQLNPPGKTMRCVFSSSPEQEGEEIKAGPVCGSAVKIT
VPPGGFVIYR

Specific function: Since Only Maltooligosaccharides Up To A Chain Length Of 6 Glucose Units Are Actively Transported Through The Cytoplasmic Membrane VIa The Membrane-Bound Complex Of Three Proteins, Malf, Malg, And Malk, Longer Maltooligosaccharides Must First Be Degraded

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=262, Percent_Identity=23.2824427480916, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1789995, Length=346, Percent_Identity=25.7225433526012, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786604, Length=505, Percent_Identity=24.7524752475248, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790687, Length=89, Percent_Identity=34.8314606741573, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322245, Length=86, Percent_Identity=40.6976744186046, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321731, Length=428, Percent_Identity=21.9626168224299, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319776, Length=428, Percent_Identity=21.9626168224299, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321726, Length=85, Percent_Identity=36.4705882352941, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24586587, Length=91, Percent_Identity=43.956043956044, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24586591, Length=91, Percent_Identity=40.6593406593407, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24586599, Length=82, Percent_Identity=39.0243902439024, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24586597, Length=82, Percent_Identity=41.4634146341463, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221330053, Length=82, Percent_Identity=37.8048780487805, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24586593, Length=91, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583745, Length=91, Percent_Identity=32.967032967033, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586589, Length=91, Percent_Identity=37.3626373626374, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45549022, Length=81, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR005323 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02806 Alpha-amylase_C; PF03714 PUD [H]

EC number: =3.2.1.1 [H]

Molecular weight: Translated: 73385; Mature: 73254

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPDSPALSPVERSLAEIRLAELTAAKTCYSSPATWEDEVLYFLMLDRFSDCREHGGFN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DVSGAPVVADGTRTTLLFRIEADANNADWQQWFEAGRGWCGGTIAGMRDKLGYLKRLGVT
CCCCCCEEECCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
AIWVSPVFRQVTGSDSYHGYGIQNFLDVDPHFGTREELRDFVADAHQLGIRVILDIILNH
EEHHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
AGDVFSYHDNQPYFYYQGWQWPVKGYRLNQGDAGSIPFSDGEAHLEISMEAAIWPVEFQS
CCCEEEEECCCCEEEECCEECCCCCEEECCCCCCCCCCCCCCEEEEEEEEEEEEEEEECC
ETTWTMKGEIRNWDVFPEYLQGDFCSLKDIDHGWAPDDPAESWDLEKRISLFRPSAALDH
CCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHH
LIKVYRFWMAYADIDGFRLDTVKHMEPGAVRYFASAIHEFAQTLGKENFPIIGEITGGRS
HHHHHHHHHHHHCCCCCEECHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
YAMQILDVTGLDAALGIGDLPDKLEFLVKGWRSPGNPDTSEQEGYFDLFCNSLLDGKNSH
EEEEEEEECCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
QWYSKHIVTMIDDHDQVGEQRKYHFCGDSPEGRKLLKAALGLNLATEGISCIYYGTEQAF
HHHHCCEEEEECCCHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHC
NGADPRSDDHSWGDVFLRECMFGGPFGSLQSTGRHFFNEEHEVYRFAGRLAEFRKSEIAL
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRGRQYLRKVSATGSEDDFVYPQPVNGEMHWVVAWSRIFAETECLCAINTSLERELTVWA
HHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEHHHHHHCCCEEEEECCCCCCCEEEEE
VVDHQLNPPGKTMRCVFSSSPEQEGEEIKAGPVCGSAVKITVPPGGFVIYR
EEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC
>Mature Secondary Structure 
TNPDSPALSPVERSLAEIRLAELTAAKTCYSSPATWEDEVLYFLMLDRFSDCREHGGFN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DVSGAPVVADGTRTTLLFRIEADANNADWQQWFEAGRGWCGGTIAGMRDKLGYLKRLGVT
CCCCCCEEECCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
AIWVSPVFRQVTGSDSYHGYGIQNFLDVDPHFGTREELRDFVADAHQLGIRVILDIILNH
EEHHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
AGDVFSYHDNQPYFYYQGWQWPVKGYRLNQGDAGSIPFSDGEAHLEISMEAAIWPVEFQS
CCCEEEEECCCCEEEECCEECCCCCEEECCCCCCCCCCCCCCEEEEEEEEEEEEEEEECC
ETTWTMKGEIRNWDVFPEYLQGDFCSLKDIDHGWAPDDPAESWDLEKRISLFRPSAALDH
CCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHH
LIKVYRFWMAYADIDGFRLDTVKHMEPGAVRYFASAIHEFAQTLGKENFPIIGEITGGRS
HHHHHHHHHHHHCCCCCEECHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
YAMQILDVTGLDAALGIGDLPDKLEFLVKGWRSPGNPDTSEQEGYFDLFCNSLLDGKNSH
EEEEEEEECCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
QWYSKHIVTMIDDHDQVGEQRKYHFCGDSPEGRKLLKAALGLNLATEGISCIYYGTEQAF
HHHHCCEEEEECCCHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHC
NGADPRSDDHSWGDVFLRECMFGGPFGSLQSTGRHFFNEEHEVYRFAGRLAEFRKSEIAL
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRGRQYLRKVSATGSEDDFVYPQPVNGEMHWVVAWSRIFAETECLCAINTSLERELTVWA
HHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEHHHHHHCCCEEEEECCCCCCCEEEEE
VVDHQLNPPGKTMRCVFSSSPEQEGEEIKAGPVCGSAVKITVPPGGFVIYR
EEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8424949; 8485150 [H]