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The map label for this gene is hsdM-1 [C]

Identifier: 21673506

GI number: 21673506

Start: 666360

End: 667955

Strand: Direct

Name: hsdM-1 [C]

Synonym: CT0675

Alternate gene names: 21673506

Gene position: 666360-667955 (Clockwise)

Preceding gene: 21673505

Following gene: 21673507

Centisome position: 30.92

GC content: 64.97

Gene sequence:

>1596_bases
ATGGCAAGATCTGATAGTGACAAGAACGGCAATGGGGGCAACCTCGGCTTCGAGGCTGAACTGTTCAAAGCCGCCGACAA
GCTGCGCGGCAACATGGAGCCCAGCGACTACAAGCACGTCGCGCTGGGTTTGATCTTCCTGAAGTACATCTCCGACGCCT
TCGAGGCCAAGCACAAGGCGCTGCTGGCCGAAGATGCACTGGCCGCCGAGGACAAGGACGAATACCTCGCCGACAACGTG
TTCTGGGTGCCAAAGGAGGCGCGCTGGTCGCACCTGCAAGCCAACGCCAAGCAGCCCACCATCGGCACCCTGATCGACGA
CGCGATGCGCGCCATCGAGAAGGACAACGCATCGCTCAAGGGCGTGCTGCCCAAGGATTACGCCCGCCCTGCGCTCAACA
AGGTGATGCTGGGGGAACTCATCGACCTGATCTCCGGCATTGGCCATCTGCTCCCCTCGCCCTCCGGGAGAGGGGCCGGG
GGTGAGGGGCAATCCTTCGACATCCTCGGGCGCGTCTATGAGTACTTCCTCGGCCAGTTCGCCGGGGCCGAAGGCAAACG
CGGCGGCGAGTTCTACACCCCGCGTTCCGTGGTGCGCGTGCTGGTGGAAATGCTGGAGCCGTACTCCGGCCGCGTGTACG
ACCCCTGCTGCGGTTCAGGCGGGATGTTTGTCCAGTCCGAGAAGTTCGTGCAGGAGCACGGCGGCCGTATTGGCGACATC
GCCATCTACGGCCAGGAATCGAACTACACCGCCTGGCGGCTGGCCAAAATGAACCTGGCCGTGCGCGGCATCGACGCCGA
CATCCGCTGGAACAACGAAGGTAGCTTCCACAAGGACGAACTGCGCGACCTCAAGGCCGACTACATCCTGGCCAACCCGC
CCTTCAACATCTCCGACTGGGGTGGCGATCGCCTGCGTGAAGACGTGCGCTGGCAGTTCGGCGTACCGCCCGTGGGCAAC
GCCAACTACGCCTGGCTCCAGCACATCTACTGGCACCTGGCCCCCAACGGCACGGCGGGCGTGGTGCTGGCCAACGGCTC
CATGAGCTCCAACCAGTCGGGCGAGGGCGAGATTCGCCGCGCCATGCTCGAAGCCGACGCGGTGGATTGCATGGTGGCGC
TGCCCGGGCAGCTCTTTTACTCCACGCAAATCCCCGCCTGCCTGTGGTTTCTGGCCCGCAACAAAAACCCCGCGAATGGC
AAAACCGGGGGGCTGCGCGACCGGCGCGGGCACGTGCTGTTCATCGACGCCCGCAAGATGGGCGTGCTGGTGGACCGCAC
CCGGCGCGAACTCAGCGACGAGGAGATCCAGAAAATCGCCCGCACCTACCACGCCTGGCGCGGCGAACCCGACGCGGGCG
ACTACGCCGACGTGGCGGGCTTCTGCAAATCCGCCACGCTGGACGAAATCCGCAAACACGGCCACGTGCTGACGCCCGGC
CGTTACGTGGGCGCAGCGGAAGTGGAAGACGACGGCGAACCCTTCGAGGAGAAGATGGCGCGGCTGGCGGCGCAGTGGCG
GCAGCAGCGGGACGAGGCGGCGAAGCTCGATGCGGCGATTGAGGCGAACCTCAAAGAACTGGGTTTCTGGGAGTGA

Upstream 100 bases:

>100_bases
CAAGAAGGATGAGGTTGACGAATGGGTGAAGGCCGGCGGCGCGGCGGAATCTTCAGATGCTGGGAAGAGCCGCAACCTAT
GATTATAAGGATCGTTACGT

Downstream 100 bases:

>100_bases
CTTCGATGAACCCAGAGGCGCTACGCAAGCTGATCGACACTGGGGAAACCCAAGCCGTCGAATTCAAAGGCGAAGAACGT
ACGCCGCTGAACGATCGCAC

Product: type I restriction system adenine methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKALLAEDALAAEDKDEYLADNV
FWVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLKGVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAG
GEGQSFDILGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDI
AIYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWQFGVPPVGN
ANYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRRAMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANG
KTGGLRDRRGHVLFIDARKMGVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPG
RYVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE

Sequences:

>Translated_531_residues
MARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKALLAEDALAAEDKDEYLADNV
FWVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLKGVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAG
GEGQSFDILGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDI
AIYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWQFGVPPVGN
ANYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRRAMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANG
KTGGLRDRRGHVLFIDARKMGVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPG
RYVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE
>Mature_530_residues
ARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKALLAEDALAAEDKDEYLADNVF
WVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLKGVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAGG
EGQSFDILGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIA
IYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWQFGVPPVGNA
NYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRRAMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANGK
TGGLRDRRGHVLFIDARKMGVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPGR
YVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=449, Percent_Identity=23.3853006681514, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58847; Mature: 58716

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLAEDALAAEDKDEYLADNVFWVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLK
HHHHHHHHCCCCHHHHHCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
GVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAGGEGQSFDILGRVYEYFLGQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEECHHHHHHHHCCCEEEE
AIYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDW
EEEECCCCCCEEEEEEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCCCCCCC
GGDRLREDVRWQFGVPPVGNANYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRR
CCHHHHHHCCEEECCCCCCCCCHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCHHHHH
AMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANGKTGGLRDRRGHVLFIDARKM
HHHHHHHHHHHEECCCHHEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHH
GVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCEECCC
RYVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
ARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLAEDALAAEDKDEYLADNVFWVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLK
HHHHHHHHCCCCHHHHHCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
GVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAGGEGQSFDILGRVYEYFLGQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEECHHHHHHHHCCCEEEE
AIYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDW
EEEECCCCCCEEEEEEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCCCCCCC
GGDRLREDVRWQFGVPPVGNANYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRR
CCHHHHHHCCEEECCCCCCCCCHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCHHHHH
AMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANGKTGGLRDRRGHVLFIDARKM
HHHHHHHHHHHEECCCHHEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHH
GVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCEECCC
RYVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]