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The map label for this gene is phoP [H]

Identifier: 21673488

GI number: 21673488

Start: 654853

End: 655563

Strand: Direct

Name: phoP [H]

Synonym: CT0656

Alternate gene names: 21673488

Gene position: 654853-655563 (Clockwise)

Preceding gene: 21673487

Following gene: 21673489

Centisome position: 30.39

GC content: 59.35

Gene sequence:

>711_bases
ATGGCTGAAACCTCCATACTGATCGTCGAAGATGACCGGAACCTTGCCGGACTCCTGAAGTACAACCTTGAAAAAGCCGG
TTACGGCTGCATTCACGCCGCCAGTGGAGAGGAGGCGCTCGACGAGTTGCAACGCCATGCCGTGAACCTCGTGCTGCTCG
ACATTATGCTGCCGGGCATTGACGGCTTCGAGGTGTGCCGCCGCATCCGCCAGAATGTGCAGTGGAGCGATCTGCCCATC
GTGATGCTGACGGCCAAGGGCGAGGAGATCGACAAGGTGTTCGGTTTCGAACTCGGTATCGACGACTATGTGGTCAAGCC
CTTCAGTCCCCGCGAGCTGAATCTCCGAATTCGCGCCATTCTCAAGCGCGATCGTCGCAACCGCAGCAATGTGCAGGAGG
TGCTCCGTTCGGGCGGTATCGAGCTCGATATCGGCCGCCACGAGGCCACGCTCGACGGCCGTCCCCTCGTTCTGACCTTG
ATGGAGTTCAAGCTGCTGGCGCTTCTGATGAAACGCAAAGGGCAGGCGCAGACGCGCGAGGTGCTCCTGAGCGACGTGTG
GGATGTGGACAAGAGCATCAATACTCGCACCATCGACACGCATGTCACGCGGCTTCGCGAAAAGCTCGGCGACGCCGGGC
GCTTCATCCGAACCGTGCGCGGCCTCGGCTACAAGTTCGACGAAAACGGAGACAATTTGAATGAAAGCTAA

Upstream 100 bases:

>100_bases
TGACCATTGCCGCCGGGAGCAGCCGCCGATTCTCGAATATGAACCGGGTCACCGGGCGGCCTGCTGGAAAATCACCTGAA
CTGAACACAACTGAACGAGC

Downstream 100 bases:

>100_bases
GCTCTCATTCAGACTTGGTCTGGTTTTTGGCCTGATCATCTTTTTTTCGCTCGCCTTCAGCTATGTTTACCAGGGGCGTC
AGCTCCGCAAGGTGCTTTTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAETSILIVEDDRNLAGLLKYNLEKAGYGCIHAASGEEALDELQRHAVNLVLLDIMLPGIDGFEVCRRIRQNVQWSDLPI
VMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRSGGIELDIGRHEATLDGRPLVLTL
MEFKLLALLMKRKGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGRFIRTVRGLGYKFDENGDNLNES

Sequences:

>Translated_236_residues
MAETSILIVEDDRNLAGLLKYNLEKAGYGCIHAASGEEALDELQRHAVNLVLLDIMLPGIDGFEVCRRIRQNVQWSDLPI
VMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRSGGIELDIGRHEATLDGRPLVLTL
MEFKLLALLMKRKGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGRFIRTVRGLGYKFDENGDNLNES
>Mature_235_residues
AETSILIVEDDRNLAGLLKYNLEKAGYGCIHAASGEEALDELQRHAVNLVLLDIMLPGIDGFEVCRRIRQNVQWSDLPIV
MLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRSGGIELDIGRHEATLDGRPLVLTLM
EFKLLALLMKRKGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGRFIRTVRGLGYKFDENGDNLNES

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=42.9824561403509, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.0134529147982, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=38.4615384615385, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=36.6812227074236, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=39.2070484581498, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=43.6123348017621, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=36.1607142857143, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=35.1694915254237, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.4821428571429, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.5991189427313, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=33.0357142857143, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=31.6964285714286, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.0512820512821, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=28.6885245901639, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26797; Mature: 26666

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETSILIVEDDRNLAGLLKYNLEKAGYGCIHAASGEEALDELQRHAVNLVLLDIMLPGI
CCCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHEEHHHCCC
DGFEVCRRIRQNVQWSDLPIVMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAI
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHH
LKRDRRNRSNVQEVLRSGGIELDIGRHEATLDGRPLVLTLMEFKLLALLMKRKGQAQTRE
HHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
VLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGRFIRTVRGLGYKFDENGDNLNES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure 
AETSILIVEDDRNLAGLLKYNLEKAGYGCIHAASGEEALDELQRHAVNLVLLDIMLPGI
CCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHEEHHHCCC
DGFEVCRRIRQNVQWSDLPIVMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAI
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHH
LKRDRRNRSNVQEVLRSGGIELDIGRHEATLDGRPLVLTLMEFKLLALLMKRKGQAQTRE
HHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
VLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGRFIRTVRGLGYKFDENGDNLNES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]