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The map label for this gene is met2

Identifier: 21673440

GI number: 21673440

Start: 607686

End: 608756

Strand: Direct

Name: met2

Synonym: CT0605

Alternate gene names: 21673440

Gene position: 607686-608756 (Clockwise)

Preceding gene: 21673439

Following gene: 21673445

Centisome position: 28.2

GC content: 59.94

Gene sequence:

>1071_bases
ATGACCCGGATGGACCATAGATCGATCATTTCCGACACTACACAATATTTTGAATCGAACGAGCCGTTACAGCTCGAACT
GGGAGGGGAGCTGCCCGGAGTGAGGGTCGCTTACCGTACCTGGGGTACGCTAAACGCAGAGAAAAGCAACGTGATTCTGG
TCTGCCACGCGCTGACCGGCAACGCCGACGCCGACAGCTGGTGGTGCGGCATGTTCGGTGAGGGACGGGCGTTCGACGAG
ACTCGGGACTTCATCGTATGCAGCAACGTGCTTGGAAGCTGCTACGGAACGACCGGGCCGATGTCGGTGAATCCGCTGAG
TGGCAGGCACTACGGTCCCGATTTTCCGCGCATTACCATTCGCGACATGGTGAATGTTCAGCGATTATTGCTTCGTTCGC
TCGGCATCGACCGGATCCGGCTCATCGTTGGTGCATCGCTTGGCGGGATGCAGGTGCTCGAATGGGGCGCAATGTATCCC
GAAATGGCCGGGGCGCTGATGCCGATGGGCGTTTCGGGTCGTCATTCGGCGTGGTGCATCGCGCAGAGCGAGGCGCAGCG
GCAGGCTATCGCCGCCGATGCGGAGTGGCAAGATGGCTGGTATGATCCGGAGGTGCAGCCACGCAAAGGACTTGCCGCCG
CGCGGATGATGGCGATGTGCACCTACCGCTGCTTCGAGAACTACCAGCAACGCTTTGGCCGCAAGCAGCGCGAGGACGGC
TTGTTCGAAGCCGAAAGCTACGTGCGTCACCAGGGCGACAAGCTGGTTGGGCGCTTTGATGCAAACACCTATATCACGCT
CACCAGAGCGATGGACATGCACGACCTCGGGCGCGGACGCGACTCCTACGAAGCGGCGCTCGGAGCGCTGAAGATGCCGG
TCGAGATTCTCTCCATCGACTCGGACGTGCTCTATCCCAGGCAGGAGCAGGAGGAACTTGCCCGCCTCATTCCCGGCTCA
CGCCTGCTTTTCCTTGACGAACCCTATGGCCACGACGCCTTTCTTATCGACACCGAGACCGTCAGCCGCATGGTCTGCGA
GTTCAAGAGGCAGTTGATAGTTGACAATTGA

Upstream 100 bases:

>100_bases
TATCGGCGGGCGTCACCGCCGATATGGTGCGCGTGTCGGTTGGTATCGAGCATATCGATGACATCAAGGCTGATTTCAGC
CAGGCTTTCGAGAATTTAGC

Downstream 100 bases:

>100_bases
TAGTTGATAATGAAAGAGGCGCGGTATTTTGCCGCGCCTCTTCTTTTGTATCCTGCCCACCTCGTTCAATCAGTTCACAA
CGTCCACCTTCACTCAATGA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTRMDHRSIISDTTQYFESNEPLQLELGGELPGVRVAYRTWGTLNAEKSNVILVCHALTGNADADSWWCGMFGEGRAFDE
TRDFIVCSNVLGSCYGTTGPMSVNPLSGRHYGPDFPRITIRDMVNVQRLLLRSLGIDRIRLIVGASLGGMQVLEWGAMYP
EMAGALMPMGVSGRHSAWCIAQSEAQRQAIAADAEWQDGWYDPEVQPRKGLAAARMMAMCTYRCFENYQQRFGRKQREDG
LFEAESYVRHQGDKLVGRFDANTYITLTRAMDMHDLGRGRDSYEAALGALKMPVEILSIDSDVLYPRQEQEELARLIPGS
RLLFLDEPYGHDAFLIDTETVSRMVCEFKRQLIVDN

Sequences:

>Translated_356_residues
MTRMDHRSIISDTTQYFESNEPLQLELGGELPGVRVAYRTWGTLNAEKSNVILVCHALTGNADADSWWCGMFGEGRAFDE
TRDFIVCSNVLGSCYGTTGPMSVNPLSGRHYGPDFPRITIRDMVNVQRLLLRSLGIDRIRLIVGASLGGMQVLEWGAMYP
EMAGALMPMGVSGRHSAWCIAQSEAQRQAIAADAEWQDGWYDPEVQPRKGLAAARMMAMCTYRCFENYQQRFGRKQREDG
LFEAESYVRHQGDKLVGRFDANTYITLTRAMDMHDLGRGRDSYEAALGALKMPVEILSIDSDVLYPRQEQEELARLIPGS
RLLFLDEPYGHDAFLIDTETVSRMVCEFKRQLIVDN
>Mature_355_residues
TRMDHRSIISDTTQYFESNEPLQLELGGELPGVRVAYRTWGTLNAEKSNVILVCHALTGNADADSWWCGMFGEGRAFDET
RDFIVCSNVLGSCYGTTGPMSVNPLSGRHYGPDFPRITIRDMVNVQRLLLRSLGIDRIRLIVGASLGGMQVLEWGAMYPE
MAGALMPMGVSGRHSAWCIAQSEAQRQAIAADAEWQDGWYDPEVQPRKGLAAARMMAMCTYRCFENYQQRFGRKQREDGL
FEAESYVRHQGDKLVGRFDANTYITLTRAMDMHDLGRGRDSYEAALGALKMPVEILSIDSDVLYPRQEQEELARLIPGSR
LLFLDEPYGHDAFLIDTETVSRMVCEFKRQLIVDN

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=214, Percent_Identity=47.196261682243, Blast_Score=219, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_CHLTE (Q8KES7)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661505.1
- ProteinModelPortal:   Q8KES7
- SMR:   Q8KES7
- GeneID:   1006252
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0605
- NMPDR:   fig|194439.1.peg.599
- TIGR:   CT0605
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   CLSK637391
- BioCyc:   CTEP194439:CT_0605-MONOMER
- BRENDA:   2.3.1.31
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 40134; Mature: 40003

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: ACT_SITE 146-146 ACT_SITE 331-331

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMDHRSIISDTTQYFESNEPLQLELGGELPGVRVAYRTWGTLNAEKSNVILVCHALTG
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEECC
NADADSWWCGMFGEGRAFDETRDFIVCSNVLGSCYGTTGPMSVNPLSGRHYGPDFPRITI
CCCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEH
RDMVNVQRLLLRSLGIDRIRLIVGASLGGMQVLEWGAMYPEMAGALMPMGVSGRHSAWCI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEE
AQSEAQRQAIAADAEWQDGWYDPEVQPRKGLAAARMMAMCTYRCFENYQQRFGRKQREDG
EHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
LFEAESYVRHQGDKLVGRFDANTYITLTRAMDMHDLGRGRDSYEAALGALKMPVEILSID
CHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHCCEEEEECC
SDVLYPRQEQEELARLIPGSRLLFLDEPYGHDAFLIDTETVSRMVCEFKRQLIVDN
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRMDHRSIISDTTQYFESNEPLQLELGGELPGVRVAYRTWGTLNAEKSNVILVCHALTG
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEECC
NADADSWWCGMFGEGRAFDETRDFIVCSNVLGSCYGTTGPMSVNPLSGRHYGPDFPRITI
CCCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEH
RDMVNVQRLLLRSLGIDRIRLIVGASLGGMQVLEWGAMYPEMAGALMPMGVSGRHSAWCI
HHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEE
AQSEAQRQAIAADAEWQDGWYDPEVQPRKGLAAARMMAMCTYRCFENYQQRFGRKQREDG
EHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
LFEAESYVRHQGDKLVGRFDANTYITLTRAMDMHDLGRGRDSYEAALGALKMPVEILSID
CHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHCCEEEEECC
SDVLYPRQEQEELARLIPGSRLLFLDEPYGHDAFLIDTETVSRMVCEFKRQLIVDN
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901