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The map label for this gene is rnr [H]

Identifier: 21673344

GI number: 21673344

Start: 517042

End: 519204

Strand: Direct

Name: rnr [H]

Synonym: CT0509

Alternate gene names: 21673344

Gene position: 517042-519204 (Clockwise)

Preceding gene: 21673343

Following gene: 21673358

Centisome position: 23.99

GC content: 58.39

Gene sequence:

>2163_bases
ATGGGCTACGGCGAGTCTCGCCAGCTTCCCGGCTTCTGGTATGTCCTGCACAAGTTGCAGGAAGAAGGCGTCATCGACAA
GGACAGCGACCGCTGCTACGGTTGGGCTGGTTTCGAGGCCGATACCTATGAGGAGCACCTCATCGAGGGGCCTCACTTTC
CGCAACCCGGCAAGGAGCGCTACAAGGTCGGTCAGATATACACCGGCAAGCTGACGACCCATCCGAACGGCTACGGCTTT
GTGGATGTCGATGGTTTTGACGACGATATTTTCATCAGTGCCGACATGCTTGGCCAGTCGCTGCATCTCGACCAGGTCGA
GGTGCAGGTCACCAAAGTACCCGAATCCTATGCTTCGCGCCAGTCGCCGCACCAGCGCTGCGAAGGCCTCGTCGTCAACG
TGATCGAACGCAGGCTTGTGACCGTGGTCGGCACGCTGCACCGCGAGAATCGCCGTTTCCTGCTCAAGCCCGATCAGCGC
AAGATTCTGCCCGAGATTCATATTCCCCTCAAGGCGGCCAAAAAGGCCAAGGCCGGTGACAAGGTGCTTGCCGGAGAGCT
GGAGTTCCTCAAGAGTGGCACTATTCAGGCCAGGGTGATCGAGATTCTTGGCACGGCGGGCGAATCACAGGTCGAGGTGA
GCGCTATCGCTCGCGGTCTCGGTATCGACGAAACCTTCGAGCCGGAGCTCTTGACCTTCGCCGAAAAGGTTCGCGAAGCA
ATTACCGATGAGGATCTGAAGGAGCGACTCGACATCCGCGACAAGGATGTTTTTACCATCGATCCGGTCGATGCGAAGGA
TTTCGACGACGCGCTCTCCATCGAGACGCTTGGCAATGGCGGCGGCTACAAGGTCGGCGTGCACATCGCCGACGTGTCGC
ACTATGTGCCGGAGAATTCGGCACTCGACAAGGAGGCCCGCAAGCGCGCGACCTCGGTCTATCTGGTTGATCGCGTGATT
CCGATGCTGCCCTCCCGCCTCTCCGAAAAGGTGTGCAGCCTTAATCCGGGGGTGGATCGCCTGGCTTTCTCGGTCTTTTT
CAACATCACCAAAAAGGGTGAGGTCACGAAGTTTGAGTTTCACAAGACGGTCATCCATTCGAAACGCCGCTTCACCTATG
AGGATGTTCAGCAGATTCTCGATGCGGGCAAGGGCGATTACTTCAGGGAGTTGCAGGCGCTCGACCAGCTCAGCAAGAAG
ATCCGTGCCCAGCGCATGGAGTCGGGCGGGCTTGAATTCGAGACCGAGGAGGTGCGCTTCAAACTTGGCAGCAATGGCGA
GCCTGTCGAGGTGATCAAGAAGGAACGGCTCGACAGCCACCGCCTGATCGAGGAGTTCATGCTGCTGGCCAACCGCACGG
TGGCTGCTTACCTGACTGCCCGTTATGCCGAGAACGAAAAGAATCCCCATCCGGTGATCTACCGCGTGCACGGCGCGCCG
CAGATGGAGAAGGTGCAGGTGCTGGCCAGCTTCGTGCGCAAGATTGGCTTTGACCTCAAGCTCGACCGCAAGGGCAAAGA
CAGCGCCACGGTGTCGTCCAAAGCGCTGCGCGAGCTGTTGCAAAAGGTGCGCGGCACCAACGTCGAGTTCCTGGTCAACG
AGCTGGTGCTGCGCTCCATGTCGAAGGCGGTTTATTCGCCGTTGAACGACGGCCACTTCGGCCTCGGTTTCGAGCACTAC
ACGCACTTTACCTCGCCCATCAGGCGCTACCCTGACCTGATCGTGCACCGCATTTTGTTCGAGTACGAAACGACGCGCAA
AAAGCGCCGCAAGGTCACGCCCGAAAGGATCAGCCAGATCACCGCGACTATCACCGAGGTGTGCCAGATCACTAACGAGC
GCGAGAAGATCGCTACCGAAGCGGAGCGCGAGTCGATCAAGCTCAAGCAGGTTGAGTACATGTCGGCGCATCTCGGCAAC
ACCTACGACGGCGTCATCACCGGTGCCACCGAATACGGCATCTACGTGCGCATGACCGACTTTGCCATCGAAGGCTTGGT
GCATATGCGCAACCTCAAGGACGACTACTATGAGTACGACGAGGCTACCTACTCACTTGTCGGCAGACGCAAACACCGCC
GCTTGCAAATCGGCCAGCGGTTGAAGGTAAAGGTGCACGAAGTCGATCTGACAAGAAGAACAATCGATCTCACGCTGGCG
TGA

Upstream 100 bases:

>100_bases
TCTTTTCAGGCGCGGTGAAACTTCGCTTGGCGCCGAGATCATTTCATTTCTGACTGACCACGAAGGCGAGCGTTTCCGCT
CGGTGGAGCTTGCCCGCAAA

Downstream 100 bases:

>100_bases
GGTAGGGTTGGATGGGCCACTTGAACACCCTGGGAACTGCCATCCCATTGCTGTAACTGTACTAATAACCATTGCTGCAA
GCTCGCTAGTGTGTCTTTGG

Product: ribonuclease II family protein

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MGYGESRQLPGFWYVLHKLQEEGVIDKDSDRCYGWAGFEADTYEEHLIEGPHFPQPGKERYKVGQIYTGKLTTHPNGYGF
VDVDGFDDDIFISADMLGQSLHLDQVEVQVTKVPESYASRQSPHQRCEGLVVNVIERRLVTVVGTLHRENRRFLLKPDQR
KILPEIHIPLKAAKKAKAGDKVLAGELEFLKSGTIQARVIEILGTAGESQVEVSAIARGLGIDETFEPELLTFAEKVREA
ITDEDLKERLDIRDKDVFTIDPVDAKDFDDALSIETLGNGGGYKVGVHIADVSHYVPENSALDKEARKRATSVYLVDRVI
PMLPSRLSEKVCSLNPGVDRLAFSVFFNITKKGEVTKFEFHKTVIHSKRRFTYEDVQQILDAGKGDYFRELQALDQLSKK
IRAQRMESGGLEFETEEVRFKLGSNGEPVEVIKKERLDSHRLIEEFMLLANRTVAAYLTARYAENEKNPHPVIYRVHGAP
QMEKVQVLASFVRKIGFDLKLDRKGKDSATVSSKALRELLQKVRGTNVEFLVNELVLRSMSKAVYSPLNDGHFGLGFEHY
THFTSPIRRYPDLIVHRILFEYETTRKKRRKVTPERISQITATITEVCQITNEREKIATEAERESIKLKQVEYMSAHLGN
TYDGVITGATEYGIYVRMTDFAIEGLVHMRNLKDDYYEYDEATYSLVGRRKHRRLQIGQRLKVKVHEVDLTRRTIDLTLA

Sequences:

>Translated_720_residues
MGYGESRQLPGFWYVLHKLQEEGVIDKDSDRCYGWAGFEADTYEEHLIEGPHFPQPGKERYKVGQIYTGKLTTHPNGYGF
VDVDGFDDDIFISADMLGQSLHLDQVEVQVTKVPESYASRQSPHQRCEGLVVNVIERRLVTVVGTLHRENRRFLLKPDQR
KILPEIHIPLKAAKKAKAGDKVLAGELEFLKSGTIQARVIEILGTAGESQVEVSAIARGLGIDETFEPELLTFAEKVREA
ITDEDLKERLDIRDKDVFTIDPVDAKDFDDALSIETLGNGGGYKVGVHIADVSHYVPENSALDKEARKRATSVYLVDRVI
PMLPSRLSEKVCSLNPGVDRLAFSVFFNITKKGEVTKFEFHKTVIHSKRRFTYEDVQQILDAGKGDYFRELQALDQLSKK
IRAQRMESGGLEFETEEVRFKLGSNGEPVEVIKKERLDSHRLIEEFMLLANRTVAAYLTARYAENEKNPHPVIYRVHGAP
QMEKVQVLASFVRKIGFDLKLDRKGKDSATVSSKALRELLQKVRGTNVEFLVNELVLRSMSKAVYSPLNDGHFGLGFEHY
THFTSPIRRYPDLIVHRILFEYETTRKKRRKVTPERISQITATITEVCQITNEREKIATEAERESIKLKQVEYMSAHLGN
TYDGVITGATEYGIYVRMTDFAIEGLVHMRNLKDDYYEYDEATYSLVGRRKHRRLQIGQRLKVKVHEVDLTRRTIDLTLA
>Mature_719_residues
GYGESRQLPGFWYVLHKLQEEGVIDKDSDRCYGWAGFEADTYEEHLIEGPHFPQPGKERYKVGQIYTGKLTTHPNGYGFV
DVDGFDDDIFISADMLGQSLHLDQVEVQVTKVPESYASRQSPHQRCEGLVVNVIERRLVTVVGTLHRENRRFLLKPDQRK
ILPEIHIPLKAAKKAKAGDKVLAGELEFLKSGTIQARVIEILGTAGESQVEVSAIARGLGIDETFEPELLTFAEKVREAI
TDEDLKERLDIRDKDVFTIDPVDAKDFDDALSIETLGNGGGYKVGVHIADVSHYVPENSALDKEARKRATSVYLVDRVIP
MLPSRLSEKVCSLNPGVDRLAFSVFFNITKKGEVTKFEFHKTVIHSKRRFTYEDVQQILDAGKGDYFRELQALDQLSKKI
RAQRMESGGLEFETEEVRFKLGSNGEPVEVIKKERLDSHRLIEEFMLLANRTVAAYLTARYAENEKNPHPVIYRVHGAPQ
MEKVQVLASFVRKIGFDLKLDRKGKDSATVSSKALRELLQKVRGTNVEFLVNELVLRSMSKAVYSPLNDGHFGLGFEHYT
HFTSPIRRYPDLIVHRILFEYETTRKKRRKVTPERISQITATITEVCQITNEREKIATEAERESIKLKQVEYMSAHLGNT
YDGVITGATEYGIYVRMTDFAIEGLVHMRNLKDDYYEYDEATYSLVGRRKHRRLQIGQRLKVKVHEVDLTRRTIDLTLA

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=554, Percent_Identity=31.4079422382672, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI190014623, Length=554, Percent_Identity=31.5884476534296, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI134288890, Length=462, Percent_Identity=32.9004329004329, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI219521928, Length=514, Percent_Identity=30.9338521400778, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI19115966, Length=608, Percent_Identity=29.1118421052632, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI156105695, Length=364, Percent_Identity=28.021978021978, Blast_Score=116, Evalue=9e-26,
Organism=Homo sapiens, GI156105693, Length=364, Percent_Identity=28.021978021978, Blast_Score=109, Evalue=7e-24,
Organism=Escherichia coli, GI87082383, Length=665, Percent_Identity=32.6315789473684, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI1787542, Length=532, Percent_Identity=28.0075187969925, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI212645896, Length=563, Percent_Identity=32.6820603907638, Blast_Score=241, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17553506, Length=515, Percent_Identity=32.4271844660194, Blast_Score=232, Evalue=7e-61,
Organism=Saccharomyces cerevisiae, GI6324552, Length=496, Percent_Identity=34.4758064516129, Blast_Score=227, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323943, Length=450, Percent_Identity=27.1111111111111, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320499, Length=560, Percent_Identity=23.75, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24649634, Length=568, Percent_Identity=32.2183098591549, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI19922976, Length=558, Percent_Identity=33.1541218637993, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24654597, Length=558, Percent_Identity=33.1541218637993, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24654592, Length=558, Percent_Identity=33.1541218637993, Blast_Score=246, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 82156; Mature: 82025

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYGESRQLPGFWYVLHKLQEEGVIDKDSDRCYGWAGFEADTYEEHLIEGPHFPQPGKER
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCHHH
YKVGQIYTGKLTTHPNGYGFVDVDGFDDDIFISADMLGQSLHLDQVEVQVTKVPESYASR
EEECEEEECEEEECCCCEEEEECCCCCCCEEEEHHHCCCCCCCCEEEEEEEECCHHHHHC
QSPHQRCEGLVVNVIERRLVTVVGTLHRENRRFLLKPDQRKILPEIHIPLKAAKKAKAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCHHHHHHCCCCC
KVLAGELEFLKSGTIQARVIEILGTAGESQVEVSAIARGLGIDETFEPELLTFAEKVREA
CEEHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ITDEDLKERLDIRDKDVFTIDPVDAKDFDDALSIETLGNGGGYKVGVHIADVSHYVPENS
HCCHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEEEEEHHHHCCCCC
ALDKEARKRATSVYLVDRVIPMLPSRLSEKVCSLNPGVDRLAFSVFFNITKKGEVTKFEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEHHH
HKTVIHSKRRFTYEDVQQILDAGKGDYFRELQALDQLSKKIRAQRMESGGLEFETEEVRF
HHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHEE
KLGSNGEPVEVIKKERLDSHRLIEEFMLLANRTVAAYLTARYAENEKNPHPVIYRVHGAP
EECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
QMEKVQVLASFVRKIGFDLKLDRKGKDSATVSSKALRELLQKVRGTNVEFLVNELVLRSM
CHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SKAVYSPLNDGHFGLGFEHYTHFTSPIRRYPDLIVHRILFEYETTRKKRRKVTPERISQI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TATITEVCQITNEREKIATEAERESIKLKQVEYMSAHLGNTYDGVITGATEYGIYVRMTD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEHH
FAIEGLVHMRNLKDDYYEYDEATYSLVGRRKHRRLQIGQRLKVKVHEVDLTRRTIDLTLA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEEC
>Mature Secondary Structure 
GYGESRQLPGFWYVLHKLQEEGVIDKDSDRCYGWAGFEADTYEEHLIEGPHFPQPGKER
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCHHH
YKVGQIYTGKLTTHPNGYGFVDVDGFDDDIFISADMLGQSLHLDQVEVQVTKVPESYASR
EEECEEEECEEEECCCCEEEEECCCCCCCEEEEHHHCCCCCCCCEEEEEEEECCHHHHHC
QSPHQRCEGLVVNVIERRLVTVVGTLHRENRRFLLKPDQRKILPEIHIPLKAAKKAKAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCHHHHHHCCCCC
KVLAGELEFLKSGTIQARVIEILGTAGESQVEVSAIARGLGIDETFEPELLTFAEKVREA
CEEHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ITDEDLKERLDIRDKDVFTIDPVDAKDFDDALSIETLGNGGGYKVGVHIADVSHYVPENS
HCCHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEEEEEHHHHCCCCC
ALDKEARKRATSVYLVDRVIPMLPSRLSEKVCSLNPGVDRLAFSVFFNITKKGEVTKFEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEHHH
HKTVIHSKRRFTYEDVQQILDAGKGDYFRELQALDQLSKKIRAQRMESGGLEFETEEVRF
HHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHEE
KLGSNGEPVEVIKKERLDSHRLIEEFMLLANRTVAAYLTARYAENEKNPHPVIYRVHGAP
EECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
QMEKVQVLASFVRKIGFDLKLDRKGKDSATVSSKALRELLQKVRGTNVEFLVNELVLRSM
CHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SKAVYSPLNDGHFGLGFEHYTHFTSPIRRYPDLIVHRILFEYETTRKKRRKVTPERISQI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TATITEVCQITNEREKIATEAERESIKLKQVEYMSAHLGNTYDGVITGATEYGIYVRMTD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEHH
FAIEGLVHMRNLKDDYYEYDEATYSLVGRRKHRRLQIGQRLKVKVHEVDLTRRTIDLTLA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]