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The map label for this gene is btuC [H]

Identifier: 21673250

GI number: 21673250

Start: 424308

End: 425396

Strand: Direct

Name: btuC [H]

Synonym: CT0411

Alternate gene names: 21673250

Gene position: 424308-425396 (Clockwise)

Preceding gene: 21673249

Following gene: 21673251

Centisome position: 19.69

GC content: 58.49

Gene sequence:

>1089_bases
ATGAGTAACGTTGCGGAACTTCGTGCCCCGGCCCATCCCTGGCCTTCGCTCGTGCCGAAAAGCGGCATGATCCTCTTTAT
GCTGATCCTGCTTGTGCTGCTCTTCATGCTCGACATTGCGCTCGGCTCGGTGTCGATTCCCCTGAAAAGCGTCGTGGCGA
TTCTGTTCGGAAGCGATCAGGAGCCTGTAGCCTGGCAGAAGATCGTGACGACGATCCGCCTGCCCAAGGCGATCACCGCG
GTGATTGCCGGTGCTGCGCTCTCGGCGAGCGGCTTGCAGATGCAGACGCTCTTTCGCAATCCGCTGGCAGGCCCCTCGGT
GCTTGGAATATCCGCCGGTGCGAGTCTCGGCGTCGCCATGGTGATGCTTGTGTCCGGATCGGCAGCCAATGCCTTCGCCA
TACGGCAACTGGGGCTGGGAGGGAGCTGGTTGATCGTGATTGCTTCATCGCTGGGAGCGGCAGCGGTGCTGCTGGTTGTG
CTTGCCATCGCGGTCAAGATCAAGGATAACGTCGTGCTGCTGATTGTCGGCATCATGGTCGGCAATATTACGGTCTCTTT
GATAAGCATCTGGCAGTATTTCAGTGAACCCGAGCAGATACAGGACTACCTTATCTGGACATTCGGCAGTCTCGGCGGTG
TTCTGGGCAATCAGCTCTGGGTGCTCGGCATCGTTGTCGGGGCGGGGCTTCTCGTTTCATTCGCCGCATCGAAGCCGCTC
AACGTGATGCTGCTTGGCGAAAATTACGCGAAAAGCCTCGGCATGAGCACCTTCTCTATCCGGATTACGGTGATTGCCGC
CACCAGCCTGCTGGCCGGAAGCGTGACCGGCTTTTGCGGTCCCATCGGCTTCATCGGCATCGCCGTGCCCCACCTGACCC
GTTCGATTCTCAACACCTCCGATCACCGTTTTCTCATGCCGAGTTCATGCCTGGTCGGGGCGATTCTGATGCTGGTCTGC
GACATCATCGCGCAGATGCCGGGCAACCAGACAACCTTGCCGATCAATGTCGTGACGGCGCTTATCGGTTCGCCGGTGGT
GATCTGGGTGATCATTCGGCAGAGAAACCTCAAATCGTCATTTGCATGA

Upstream 100 bases:

>100_bases
CTGATTCTAAAGGATCTGGTGATGATTCTTCATCCGGGTCTTCTTCGCGCTCACGGTATCGGTGAGGGTGAACTCACCTT
TTTCCAGGAGGTGAAGTAAC

Downstream 100 bases:

>100_bases
GCGATAGCATGATACAGACTCGCAACCTTGCCATCGGCTACCAGTTGCGACAGCGGGAGTTCATCGCTTGGCGCAAACCG
TCGCATCCGGCCTCGACAGT

Product: iron(III) ABC transporter, permease protein, putative

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSNVAELRAPAHPWPSLVPKSGMILFMLILLVLLFMLDIALGSVSIPLKSVVAILFGSDQEPVAWQKIVTTIRLPKAITA
VIAGAALSASGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLVSGSAANAFAIRQLGLGGSWLIVIASSLGAAAVLLVV
LAIAVKIKDNVVLLIVGIMVGNITVSLISIWQYFSEPEQIQDYLIWTFGSLGGVLGNQLWVLGIVVGAGLLVSFAASKPL
NVMLLGENYAKSLGMSTFSIRITVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILNTSDHRFLMPSSCLVGAILMLVC
DIIAQMPGNQTTLPINVVTALIGSPVVIWVIIRQRNLKSSFA

Sequences:

>Translated_362_residues
MSNVAELRAPAHPWPSLVPKSGMILFMLILLVLLFMLDIALGSVSIPLKSVVAILFGSDQEPVAWQKIVTTIRLPKAITA
VIAGAALSASGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLVSGSAANAFAIRQLGLGGSWLIVIASSLGAAAVLLVV
LAIAVKIKDNVVLLIVGIMVGNITVSLISIWQYFSEPEQIQDYLIWTFGSLGGVLGNQLWVLGIVVGAGLLVSFAASKPL
NVMLLGENYAKSLGMSTFSIRITVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILNTSDHRFLMPSSCLVGAILMLVC
DIIAQMPGNQTTLPINVVTALIGSPVVIWVIIRQRNLKSSFA
>Mature_361_residues
SNVAELRAPAHPWPSLVPKSGMILFMLILLVLLFMLDIALGSVSIPLKSVVAILFGSDQEPVAWQKIVTTIRLPKAITAV
IAGAALSASGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLVSGSAANAFAIRQLGLGGSWLIVIASSLGAAAVLLVVL
AIAVKIKDNVVLLIVGIMVGNITVSLISIWQYFSEPEQIQDYLIWTFGSLGGVLGNQLWVLGIVVGAGLLVSFAASKPLN
VMLLGENYAKSLGMSTFSIRITVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILNTSDHRFLMPSSCLVGAILMLVCD
IIAQMPGNQTTLPINVVTALIGSPVVIWVIIRQRNLKSSFA

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=299, Percent_Identity=35.1170568561873, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790741, Length=298, Percent_Identity=30.8724832214765, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790740, Length=336, Percent_Identity=27.9761904761905, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786347, Length=325, Percent_Identity=30.1538461538462, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786805, Length=322, Percent_Identity=31.6770186335404, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786804, Length=322, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37803; Mature: 37672

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVAELRAPAHPWPSLVPKSGMILFMLILLVLLFMLDIALGSVSIPLKSVVAILFGSDQ
CCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
EPVAWQKIVTTIRLPKAITAVIAGAALSASGLQMQTLFRNPLAGPSVLGISAGASLGVAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHH
VMLVSGSAANAFAIRQLGLGGSWLIVIASSLGAAAVLLVVLAIAVKIKDNVVLLIVGIMV
HHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
GNITVSLISIWQYFSEPEQIQDYLIWTFGSLGGVLGNQLWVLGIVVGAGLLVSFAASKPL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVMLLGENYAKSLGMSTFSIRITVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILNTS
EEEEECCHHHHHCCCCEEEEEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRFLMPSSCLVGAILMLVCDIIAQMPGNQTTLPINVVTALIGSPVVIWVIIRQRNLKSS
CCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCEEEEEEEECCCCCCC
FA
CC
>Mature Secondary Structure 
SNVAELRAPAHPWPSLVPKSGMILFMLILLVLLFMLDIALGSVSIPLKSVVAILFGSDQ
CCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
EPVAWQKIVTTIRLPKAITAVIAGAALSASGLQMQTLFRNPLAGPSVLGISAGASLGVAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHH
VMLVSGSAANAFAIRQLGLGGSWLIVIASSLGAAAVLLVVLAIAVKIKDNVVLLIVGIMV
HHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
GNITVSLISIWQYFSEPEQIQDYLIWTFGSLGGVLGNQLWVLGIVVGAGLLVSFAASKPL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVMLLGENYAKSLGMSTFSIRITVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILNTS
EEEEECCHHHHHCCCCEEEEEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRFLMPSSCLVGAILMLVCDIIAQMPGNQTTLPINVVTALIGSPVVIWVIIRQRNLKSS
CCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCEEEEEEEECCCCCCC
FA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA