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The map label for this gene is sugE [H]

Identifier: 21673213

GI number: 21673213

Start: 385614

End: 385934

Strand: Direct

Name: sugE [H]

Synonym: CT0374

Alternate gene names: 21673213

Gene position: 385614-385934 (Clockwise)

Preceding gene: 21673212

Following gene: 21673215

Centisome position: 17.89

GC content: 61.99

Gene sequence:

>321_bases
GTGGCGTGGGTGATGCTGTTTGTGGCCGGGCTGTTCGAGTGTGCCTGGGCGGTGGGGTTGAAATATTCCGAAGGGTTCAC
GCGGCCCGTGCCGTCGGTGCTGACGATTGCGGCGATGCTGGTGAGCTTCTGGCTGCTCTCCGTGGCGATGAAAATCGTGC
CGGTCGGCACAGCCTACGCCGTCTGGACTGGTATCGGCGCGGCGGGTGTTGCCGTGGCGGGGATTCTGCTTTTCAACGAA
CCGCGCGATCTGGCGCGAGTTTTCTGCATTTTTCTGATTATCGCTGGTGTCGCTGGGTTGCGGGTGCTGGCTGGGAAGTA
G

Upstream 100 bases:

>100_bases
CTCGATTCTGACCGTGAGAAGCGCTGGGTGAAAGTGTAGTCGATGGATGATTCGGTCGATCTGTCCCGTAAATGATGTTA
TAACCAGCAGGAACTGAATC

Downstream 100 bases:

>100_bases
CTGGGAATTGGGTGGACGGGGTGGGCAAATGGAAGAAGGTTCTGTCCGCAGTGTCCGCTTAGTCCACTTTTTTCTTCACC
CCGCTTCGTCCTCCCAGCAC

Product: SugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAWVMLFVAGLFECAWAVGLKYSEGFTRPVPSVLTIAAMLVSFWLLSVAMKIVPVGTAYAVWTGIGAAGVAVAGILLFNE
PRDLARVFCIFLIIAGVAGLRVLAGK

Sequences:

>Translated_106_residues
MAWVMLFVAGLFECAWAVGLKYSEGFTRPVPSVLTIAAMLVSFWLLSVAMKIVPVGTAYAVWTGIGAAGVAVAGILLFNE
PRDLARVFCIFLIIAGVAGLRVLAGK
>Mature_105_residues
AWVMLFVAGLFECAWAVGLKYSEGFTRPVPSVLTIAAMLVSFWLLSVAMKIVPVGTAYAVWTGIGAAGVAVAGILLFNEP
RDLARVFCIFLIIAGVAGLRVLAGK

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=54.9019607843137, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI1786755, Length=85, Percent_Identity=40, Blast_Score=63, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11204; Mature: 11073

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVMLFVAGLFECAWAVGLKYSEGFTRPVPSVLTIAAMLVSFWLLSVAMKIVPVGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VWTGIGAAGVAVAGILLFNEPRDLARVFCIFLIIAGVAGLRVLAGK
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWVMLFVAGLFECAWAVGLKYSEGFTRPVPSVLTIAAMLVSFWLLSVAMKIVPVGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VWTGIGAAGVAVAGILLFNEPRDLARVFCIFLIIAGVAGLRVLAGK
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA