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The map label for this gene is cusC [C]

Identifier: 21673215

GI number: 21673215

Start: 388110

End: 389420

Strand: Direct

Name: cusC [C]

Synonym: CT0376

Alternate gene names: 21673215

Gene position: 388110-389420 (Clockwise)

Preceding gene: 21673213

Following gene: 21673216

Centisome position: 18.01

GC content: 60.11

Gene sequence:

>1311_bases
GTGTCTGTCAACGTGTTTATAAATTATATCCGGATCATGAGACGACTTCGCCGAACTTTTGTCATTGTAGCAGTGCTCTG
TTTTGTCTGCCTGCCAAAGGCTCCCGTACTGGCTGTTGAAACGCTTGACTGGGCGCAGTGTCTTGCCGAAGCGGCCGGGC
ATCATCCCGATCTGCGTTCGGCGGCGGAAAGCGTCCGGCAGTCCGAGGAGCAGCGAAATAGTGTCAAGGGTGGAATGCTT
CCGTCCGTCAGCGCGTCGGCGGGGGGCGAACGTTCGGGTTCGAGCGCTGCGGCTCCGGTGGGGGCGTGGTCGTACGGCGT
CAATGCGAGCCAGTTGCTCTACGATGGCGCGAAAACTTCCAGCGAGGTGAAGTCCGCTACCGAAACACTCAAGGCGTCGA
AGTATAATGAAAGCAAGGTTTCTGTCGCTACGCGCTATGCTTTGCGCACGGCGTTCGTCCAGCTTCTGACCGCGCAGAAA
CAGGTGGCGCTCGCAGAAGAGATTGCAACGAAAAGAAAGCAGGAGTTGCGCCTGGTCGCCCTGCTTTATAAATCGGGCAC
GGAAAATATCGGCTCGCTCAGCAAAGCCCAGGCTGACCTCGGCGAGGCGGAGTTCGAGGTGGCGCAGGCAAGGCGCGCGC
TCGATCTTGCTCAGATGGTACTTAGCACTCAGCTTGGTCGCCGCAGCTTCACGCCGATCCGCGTGACCGGGCAGTTCACG
GCCAGCGAACAGACCCGCACACCGCCCGATTTCGACAGCATCGCACGGAACAATCCGGCCTACCTCGAACTCACCGCGCA
AAAGAGTGCCGCCGGATACAGCTTGCAGGCAGCGCGGAGCGCGTTCATGCCGTCGGTTTACCTGAGCACCGGCTTCGGCA
ATAGCGCATTCCGGCAGCTTCCGCCCGACCGCACCGACTGGCAGGCGGGCATCGACGTGTCGGTGCCGATCTACGCGGGC
GGCTCCGGCAAGGCAGGCGTGGCCAAGGCGCGGGCGGTGGTTAACCAGTTGAGCGCCGACGAGGAGAGCCTTTATCTGTC
GCTCAAACGGAGCCTTGCGCAGGCGTGGAAGACTTTCATCGACGCCTCCGGTAACGTGGATGTCCAGAAAAAATATCTCG
ACGCCGCCTCCGAGCGGGCGCGCATCGCTGACGCGCAGTACTCGGCGGGACTGATTTCGTTCAACGACTGGACCATTATC
GAAGACAATCTCGTCACCGCGAAAAAATCATATCTCAACGCCCAGTCCAATCTGCTGACCGCCGAGGCGGCCTGGGTTCA
GGCAAAAGGAGGCACTCTTGAAAGCAGGTAA

Upstream 100 bases:

>100_bases
TAAAGCGCCATGCCCTCTAAGGATTCCGGTTATGTGGCCGGTCTTTGGCTGTTTTTCCCATGGTCGCTGGAAACAGGAGG
TTGCAGCGTCAAACCCGTGA

Downstream 100 bases:

>100_bases
ACCGCAACTCATCTGGGGGGCAGTGGCCGTCGTCATTGCTCTGGTCGCCGGTTCTGTTGTGTACAGAACAGTGTTTGTCG
GCAAGCCGAAAATTTCGTAC

Product: FusA/NodT family protein

Products: NA

Alternate protein names: FusA/NodT Family Protein; Outer Membrane Protein; Outer Membrane Efflux Protein lC

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSVNVFINYIRIMRRLRRTFVIVAVLCFVCLPKAPVLAVETLDWAQCLAEAAGHHPDLRSAAESVRQSEEQRNSVKGGML
PSVSASAGGERSGSSAAAPVGAWSYGVNASQLLYDGAKTSSEVKSATETLKASKYNESKVSVATRYALRTAFVQLLTAQK
QVALAEEIATKRKQELRLVALLYKSGTENIGSLSKAQADLGEAEFEVAQARRALDLAQMVLSTQLGRRSFTPIRVTGQFT
ASEQTRTPPDFDSIARNNPAYLELTAQKSAAGYSLQAARSAFMPSVYLSTGFGNSAFRQLPPDRTDWQAGIDVSVPIYAG
GSGKAGVAKARAVVNQLSADEESLYLSLKRSLAQAWKTFIDASGNVDVQKKYLDAASERARIADAQYSAGLISFNDWTII
EDNLVTAKKSYLNAQSNLLTAEAAWVQAKGGTLESR

Sequences:

>Translated_436_residues
MSVNVFINYIRIMRRLRRTFVIVAVLCFVCLPKAPVLAVETLDWAQCLAEAAGHHPDLRSAAESVRQSEEQRNSVKGGML
PSVSASAGGERSGSSAAAPVGAWSYGVNASQLLYDGAKTSSEVKSATETLKASKYNESKVSVATRYALRTAFVQLLTAQK
QVALAEEIATKRKQELRLVALLYKSGTENIGSLSKAQADLGEAEFEVAQARRALDLAQMVLSTQLGRRSFTPIRVTGQFT
ASEQTRTPPDFDSIARNNPAYLELTAQKSAAGYSLQAARSAFMPSVYLSTGFGNSAFRQLPPDRTDWQAGIDVSVPIYAG
GSGKAGVAKARAVVNQLSADEESLYLSLKRSLAQAWKTFIDASGNVDVQKKYLDAASERARIADAQYSAGLISFNDWTII
EDNLVTAKKSYLNAQSNLLTAEAAWVQAKGGTLESR
>Mature_435_residues
SVNVFINYIRIMRRLRRTFVIVAVLCFVCLPKAPVLAVETLDWAQCLAEAAGHHPDLRSAAESVRQSEEQRNSVKGGMLP
SVSASAGGERSGSSAAAPVGAWSYGVNASQLLYDGAKTSSEVKSATETLKASKYNESKVSVATRYALRTAFVQLLTAQKQ
VALAEEIATKRKQELRLVALLYKSGTENIGSLSKAQADLGEAEFEVAQARRALDLAQMVLSTQLGRRSFTPIRVTGQFTA
SEQTRTPPDFDSIARNNPAYLELTAQKSAAGYSLQAARSAFMPSVYLSTGFGNSAFRQLPPDRTDWQAGIDVSVPIYAGG
SGKAGVAKARAVVNQLSADEESLYLSLKRSLAQAWKTFIDASGNVDVQKKYLDAASERARIADAQYSAGLISFNDWTIIE
DNLVTAKKSYLNAQSNLLTAEAAWVQAKGGTLESR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47013; Mature: 46881

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNVFINYIRIMRRLRRTFVIVAVLCFVCLPKAPVLAVETLDWAQCLAEAAGHHPDLRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCHHH
AAESVRQSEEQRNSVKGGMLPSVSASAGGERSGSSAAAPVGAWSYGVNASQLLYDGAKTS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHCCCCCH
SEVKSATETLKASKYNESKVSVATRYALRTAFVQLLTAQKQVALAEEIATKRKQELRLVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYKSGTENIGSLSKAQADLGEAEFEVAQARRALDLAQMVLSTQLGRRSFTPIRVTGQFT
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
ASEQTRTPPDFDSIARNNPAYLELTAQKSAAGYSLQAARSAFMPSVYLSTGFGNSAFRQL
CCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHC
PPDRTDWQAGIDVSVPIYAGGSGKAGVAKARAVVNQLSADEESLYLSLKRSLAQAWKTFI
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DASGNVDVQKKYLDAASERARIADAQYSAGLISFNDWTIIEDNLVTAKKSYLNAQSNLLT
CCCCCCHHHHHHHHHHHHHHHHHCCHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCEEE
AEAAWVQAKGGTLESR
EHHHEEEECCCCCCCC
>Mature Secondary Structure 
SVNVFINYIRIMRRLRRTFVIVAVLCFVCLPKAPVLAVETLDWAQCLAEAAGHHPDLRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCHHH
AAESVRQSEEQRNSVKGGMLPSVSASAGGERSGSSAAAPVGAWSYGVNASQLLYDGAKTS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHCCCCCH
SEVKSATETLKASKYNESKVSVATRYALRTAFVQLLTAQKQVALAEEIATKRKQELRLVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYKSGTENIGSLSKAQADLGEAEFEVAQARRALDLAQMVLSTQLGRRSFTPIRVTGQFT
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
ASEQTRTPPDFDSIARNNPAYLELTAQKSAAGYSLQAARSAFMPSVYLSTGFGNSAFRQL
CCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHC
PPDRTDWQAGIDVSVPIYAGGSGKAGVAKARAVVNQLSADEESLYLSLKRSLAQAWKTFI
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DASGNVDVQKKYLDAASERARIADAQYSAGLISFNDWTIIEDNLVTAKKSYLNAQSNLLT
CCCCCCHHHHHHHHHHHHHHHHHCCHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCEEE
AEAAWVQAKGGTLESR
EHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA